Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Utilization of statins and LDL-cholesterol target attainment in Turkish patients with type 2 diabetes - a nationwide cross-sectional study (TEMD dyslipidemia study)
Lipids in Health and Disease · Aralık 2020
YÖKSİS Kayıtları
Utilization of statins and LDL-cholesterol target attainment in Turkish patients with type 2 diabetes - a nationwide cross-sectional study (TEMD dyslipidemia study)
Lipids in Health and Disease · 2020 SCI-Expanded
PROFESÖR SÜLEYMAN BALDANE →
Makale Bilgileri
DergiLipids in Health and Disease
Yayın TarihiAralık 2020
Cilt / Sayfa19
Scopus ID2-s2.0-85095847674
Erişim🔓 Açık Erişim
Özet
Background: Attaining acceptable levels of LDL Cholesterol (LDL-C) significantly improves cardiovascular (CV) outcomes in patients with type 2 diabetes mellitus (T2DM). The LDL-C target attainment and the characteristics of patients attaining these targets were investigated in this study. Furthermore, the reasons for not choosing statins and the physicians’ attitudes on the treatment of diabetic dyslipidemia were also examined. Methods: A nationwide, cross-sectional survey was conducted in tertiary centers for diabetes management. Adult patients with T2DM, who were under follow-up for at least a year in outpatient clinics, were consecutively enrolled for the study. LDL-C goals were defined as below 70 mg/dL for patients with macrovascular complications or diabetic nephropathy, and below 100 mg/dL for other patients. Data about lipid-lowering medications were self-reported. Results: A total of 4504 patients (female: 58.6%) were enrolled for the study. The mean HbA1c and diabetes duration was 7.73 ± 1.74% and 10.9 ± 7.5 years, respectively. The need for statin treatment was 94.9% (n = 4262); however, only 42.4% (n = 1807) of these patients were under treatment, and only 24.8% (n = 448) of these patients achieved LDL-C targets. The main reason for statin discontinuation was negative media coverage (87.5%), while only a minority of patients (12.5%) mentioned side effects. Physicians initiated lipid-lowering therapy in only 20.3% of patients with high LDL-C levels. It was observed that the female gender was a significant independent predictor of not attaining LDL-C goals (OR: 0.70, 95% CI: 0.59–0.83). Conclusions: Less than 50 % of patients with T2DM who need statins were under treatment, and only a quarter of them attained their LDL-C targets. There exists a significant gap between the guideline recommendations and the real-world evidence in the treatment of dyslipidemia in T2DM.
Yazarlar (100)
1
Fahri Bayram
2
Alper Sonmez
3
Cem Haymana
4
Tevfik Sabuncu
ORCID: 0000-0001-6504-5355
5
Oğuzhan Sıtkı Dizdar
6
Eren Gürkan
ORCID: 0000-0002-3118-4549
7
Ayse Kargili Carlioglu
8
Kemal Ağbaht
ORCID: 0000-0003-3122-5491
9
Didem Ozdemir
10
Ibrahim Demirci
ORCID: 0000-0002-6808-8550
11
Cem Barcin
12
Serpil Salman
13
Tamer Tetiker
14
Mustafa Kemal Balci
15
Nur Kebapçi
16
Canan Ersoy
17
Volkan Demirhan Yumuk
18
Peter P. Toth
19
Ilhan Satman
20
Sibel Güldiken
21
Semra Aytürk
22
Murat Yilmaz
23
M. Asik
24
Nevin Dinççağ
25
Ramazan Çakmak
26
Fulya Türker
27
Cemile İdiz
28
Hülya Hacişahinoğullari
ORCID: 0000-0001-9989-6473
29
Elif Bağdemir
30
Büşra Yildiz
31
Özlem Haliloğlu
32
Seda Sancak
33
Levent Özsari
34
Eylem Çağiltay
35
Oğuzhan Deyneli
ORCID: 0000-0001-6582-7031
36
Eren İmre
ORCID: 0000-0003-4044-7133
37
Mustafa Sait Gonen
38
Şerife Nur Boysan
39
Yüksel Altuntaş
40
Feyza Yener Öztürk
41
Meral Mert
42
Hamide Pişkinpaşa
43
Hasan Aydin
44
Şazi İmamoğlu
45
Özen Öz Gül
46
Sinem Kucuksarac Kiyici
47
B. Cetinarslan
48
Alev Selek
ORCID: 0000-0002-0646-8697
49
Teoman Doğru
50
Ali Kirik
51
Belgin Efe
52
Ahmet Kaya
53
İlker Çordan
54
Süleyman Baldane
55
Cem Onur Kirac
56
Zehra Çapa
57
M. Cesur
58
İlhan Yetkin
59
Demet Çorapçioğlu
ORCID: 0000-0003-0940-9147
60
Şule Canlar
61
Okan Bülent Yildiz
62
Süleyman Nahit Şendur
63
Bekir Cakir
64
Ahmet Çorakçi
65
Mustafa Kutlu
66
Neslihan Başçil Tütüncü
67
Yusuf Bozkus
ORCID: 0000-0002-6976-6659
68
Erman Çakal
ORCID: 0000-0003-4455-7276
69
Berrin Demirbaş
70
Sibel Ertek
71
Mustafa Altay
72
Murat Dağdeviren
73
Amir Hassein Abedi
74
S. Cetinkalp
75
Hatice Özişik
76
Gonca Örük
77
Serkan Yener
78
B. Ozgen Saydam
79
Engin Güney
80
Mustafa Ünübol
81
Güzin Fidan Yaylali
82
Şenay Topsakal
83
Zeliha Hekimsoy
84
Gülhan Akbaba
85
I. Aslan
86
Şefika Dalkiran
87
Esen Akbay
88
Kamile Gul
89
Müge Özsan Yilmaz
90
Emre Bozkirli
91
Seher Çetinkaya Altuntaş
92
Aysegul Atmaca
93
Elif Tutku Durmuş
94
Türkan Mete
95
Faruk Kutlutürk
96
Ferit Kerim Kucukler
97
Oguz Dikbas
98
Safak Akin
99
Irfan Nuhoglu
100
Halil Önder Ersöz
Anahtar Kelimeler
Dyslipidemia
Lipid-lowering treatments
Low-density lipoprotein cholesterol target attainment
Physician inertia
Physicians’ attitudes
Statin cessation
Type 2 diabetes mellitus
Kurumlar
Akdeniz Üniversitesi
Antalya Turkey
Ankara Güven Hastanesi
Ankara Turkey
Ankara Üniversitesi
Ankara Turkey
Ankara Yildirim Beyazit University
Ankara Turkey
Antakya Defne Hospital
Hatay Turkey
Aydin Adnan Menderes University
Aydin Turkey
Balikesir Üniversitesi
Balikesir Turkey
Başkent Üniversitesi
Ankara Turkey
Bayindir Hospital
Ankara Turkey
Bursa Uludağ Üniversitesi
Bursa Turkey
Çanakkale Onsekiz Mart Üniversitesi
Canakkale Turkey
CGH Medical Center
Sterling United States
Corlu REYAP Private Hospital
Corlu Turkey
Çukurova Üniversitesi Tip Fakültesi
Adana Turkey
Demiroglu Bilim University
Istanbul Turkey
Dokuz Eylül Üniversitesi
Izmir Turkey
Ege Üniversitesi
Izmir Turkey
Erciyes University, Faculty of Medicine
Kayseri Turkey
Erzurum Training and Research Hospital
Erzurum Turkey
Eskişehir Osmangazi Üniversitesi
Eskisehir Turkey
Gazi Üniversitesi
Ankara Turkey
Giresun Üniversitesi
Giresun Turkey
Hacettepe Üniversitesi
Ankara Turkey
Harran University, Faculty of Medicine
Sanliurfa Turkey
Hitit University
Corum Turkey
İstanbul Tıp Fakültesi
Istanbul Turkey
İstanbul University-Cerrahpaşa Cerrahpaşa Faculty of Medicine
Istanbul Turkey
Johns Hopkins University School of Medicine
Baltimore United States
Karadeniz Technical University
Trabzon Turkey
Kayseri Training and Research Hospital
Kayseri Turkey
Kocaeli Üniversitesi
İzmit Turkey
KSU Medical School
Kahramanmaras Turkey
Liv Hospital
Istanbul Turkey
Manisa Celâl Bayar Üniversitesi
Manisa Turkey
Marmara Üniversitesi Tip Fakültesi
Istanbul Turkey
Mersin Üniversitesi Tip Fakültesi
Mersin Turkey
Muğla Sıtkı Koçman Üniversitesi
Mugla Turkey
Mustafa Kemal Üniversitesi
Antakya Turkey
Necmettin Erbakan Üniversitesi
Meram Turkey
Ondokuz Mayis Üniversitesi
Samsun Turkey
Pamukkale Üniversitesi
Denizli Turkey
Private Memorial Hospital
Turkey
Recep Tayyip Erdogan University
Rize Turkey
Selçuk Üniversitesi
Selçuklu Turkey
TOBB University
Turkey
Tokat Gaziosmanpaşa Üniversitesi
Tokat Turkey
Trakya Üniversitesi
Edirne Turkey
Ufuk Universitési
Ankara Turkey
University of Health Sciences
Istanbul Turkey
Yeditepe University
Istanbul Turkey
Metrikler
17
Atıf
100
Yazar
7
Anahtar Kelime