Scopus
YÖKSİS Eşleşti
Comparison of developmental outcomes in children with permanent and transient congenital hypothyroidism
Journal of Pediatric Endocrinology and Metabolism · Nisan 2023
YÖKSİS Kayıtları
Comparison of developmental outcomes in children with permanent and transient congenital hypothyroidism
JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM · 2023 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ MEHMET AKİF BÜYÜKAVCI →
Makale Bilgileri
DergiJournal of Pediatric Endocrinology and Metabolism
Yayın TarihiNisan 2023
Cilt / Sayfa36 · 364-370
Scopus ID2-s2.0-85152165514
Özet
Objectives: Congenital hypothyroidism (CH) is still one of the most common causes of preventable cognitive impairment in children, and its early detection and treatment prevent irreversible neurodevelopmental delay. Depending on the underlying cause, cases with CH may be transient or permanent. This study aimed to compare the developmental evaluation results of transient and permanent CH patients and to reveal any differences. Methods: A total of 118 patients with CH, who were followed up jointly in pediatric endocrinology and developmental pediatrics clinics, were included. The patients' progress was evaluated per the International Guide for Monitoring Child Development (GMCD). Results: Of the cases, 52 (44.1%) were female, and 66 (55.9%) were male. While 20 (16.9%) cases were diagnosed with permanent CH, 98 (83.1%) were diagnosed with transient CH. According to the results of the developmental evaluation made with GMCD, the development of 101 (85.6%) children was compatible with their age, while 17 (14.4%) children had delays in at least one developmental area. All 17 patients had a delay in expressive language. Developmental delay was detected in 13 (13.3%) of those with transient CH and 4 (20%) with permanent CH. Conclusions: There is difficulty in expressive language in all cases of CH with developmental delay. No significant difference was found between the developmental evaluations of permanent and transient CH cases. The results revealed the importance of developmental follow-up, early diagnosis and interventions in those children. GMCD is thought to be an important guide to help monitoring the development of patients with CH.
Yazarlar (2)
1
Mehmet Akif Büyükavcı
ORCID: 0000-0001-6884-1832
2
Ismail Dundar
ORCID: 0000-0003-1468-6405
Anahtar Kelimeler
congenital hypothyroidism
developmental delay
language development
Kurumlar
Inönü Üniversitesi Tip Fakültesi
Malatya Turkey
Metrikler
2
Atıf
2
Yazar
3
Anahtar Kelime