Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Evaluation of von Willebrand factor in dogs with parvoviral enteritis
Ankara Universitesi Veteriner Fakultesi Dergisi · Ocak 2025
YÖKSİS Kayıtları
Evaluation of Von Willebrand Factor in Dogs with Parvoviral Enteritis
Ankara Üniversitesi Veteriner Fakültesi Dergisi · 2025 SCI-Expanded
PROFESÖR MUTLU SEVİNÇ →
Makale Bilgileri
DergiAnkara Universitesi Veteriner Fakultesi Dergisi
Yayın TarihiOcak 2025
Cilt / Sayfa72 · 139-144
Scopus ID2-s2.0-105001958370
Erişim🔓 Açık Erişim
Özet
Canine parvoviral enteritis may lead to coagulopathy in various ways. In recent years, the importance of the von Willebrand factor has become the focus of more attention in infectious diseases. This study aimed to determine the significance of von Willebrand factor level and coagulation parameters in dogs with parvoviral enteritis. The experimental group of this study consisted of 20 dogs with parvoviral enteritis of different breeds aged 2-6 months, and the control group consisted of 10 healthy dogs aged 2-6 months. Blood samples were taken from the dogs included in the experimental group at the 0th hour, 24th hour and before discharge, and only at the 0th hour from the healthy puppies in the control group The 0th and 24th hour von Willebrand factor values of the trial were significantly higher than the control group. The 0th hour Prothrombin Time of the trial was significantly prolonged compared to the control group. The 0th hour Activated Partial Thromboplastin Time value of the trial was significantly prolonged compared to the before-discharge and control group. The before-discharge fibrinogen level was considerably lower than at 0th and 24th hours of the trial. In conclusion, von Willebrand factor concentrations, which increase significantly in dogs with parvoviral enteritis compared to healthy animals, can be evaluated as an acute phase protein. Prolongation of Prothrombin Time and Activated Partial Thromboplastin Time and no significant change in fibrinogen and D-dimer values demonstrated that dogs with parvoviral enteritis were in the hypercoagulation state without disseminated intravascular coagulation.
Yazarlar (2)
1
Erman Koral
2
Mutlu Sevinc
Anahtar Kelimeler
Acute phase protein
Canine
Coagulation profile
Parvoviral enteritis
Von Willebrand factor
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey