Scopus
Community-acquired methicillin-resistant staphylococcus Aureus and genotypes among university students in Turkey
Southeast Asian Journal of Tropical Medicine and Public Health · Ocak 2015
Makale Bilgileri
DergiSoutheast Asian Journal of Tropical Medicine and Public Health
Yayın TarihiOcak 2015
Cilt / Sayfa45 · 1401-1409
Scopus ID2-s2.0-84944897449
Özet
Nasal carriage of Staphylococcus aureus is an important risk factor for nosocomial and community-acquired staphylococcal infections. We investigate the prevalence of community-acquired methicillin-sensitive (CA-MSSA) and -resistant (CA-MRSA), including inducible dormant (ID)-MRSA S. aureus, and genotypes of MRSA strains of nasal cultures from 1,108 university students attending Selcuk University, Turkey. Risk factors were based on replies to a questionnaire. S. aureus was identified using conventional culture methods and a Stapyloslide® latex test. Antibiotic susceptibility and methicillin resistance were determined by a disk diffusion method, and vancomycin susceptibility was performed using an E-test. Identification of mecA and SCCmec types were conducted by PCR and genotypes by pulse field gel-electrophoresis (PFGE). Prevalence of S. aureus was 17%, with 9% being MRSA. Two isolates were SCCmec type III, 11 were SCCmec variant IIIA and one SCCmec type IV. No ID-MRSA was detected. The majority of the isolates were resistant to penicillin and no strain was resistant to vancomycin. Two MRSA strains were PFGE pulsotype A, 9 pulsotype B, 2 pulsotype C, 1 pulsotype D and 3 pulsotype E. Presence of permanent catheter and use of antibiotics in the previous month were risk factors for MSSA colonization and association with medical facilities were risk factors for MRSA carriers. There is a need for multicenter studies in Turkey to investigate CA- and ID-MRSA prevalence and nosocomial infections.
Yazarlar (4)
1
Gamze Demirel
2
Duygu Findik
3
Hatice Türk Dağı
4
Ugur Arslan
Anahtar Kelimeler
CA-MRSA
ID-MRSA
Nasal colonization
Risk factors
Staphylococcus aureus
Turkey
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
8
Atıf
4
Yazar
6
Anahtar Kelime