Scopus
YÖKSİS Eşleşti
Enthesitis and its relationship with disease activity, functional status, and quality of life in psoriatic arthritis: a multi-center study
Rheumatology International · Şubat 2020
YÖKSİS Kayıtları
Enthesitis and its relationship with disease activity, functional status, and quality of life in psoriatic arthritis: a multi-center study
Rheumatology International · 2020 SCI-Expanded
PROFESÖR İLKNUR ALBAYRAK GEZER →
Makale Bilgileri
DergiRheumatology International
Yayın TarihiŞubat 2020
Cilt / Sayfa40 · 283-294
Scopus ID2-s2.0-85075857505
Özet
Psoriatic arthritis (PsA) is an inflammatory arthritis with distinct phenotypic subtypes. Enthesitis is assigned as a hallmark of the disease, given its significant relations to disease activity and quality of life. Our objective is to evaluate the prevalence of enthesitis and its association with some clinical parameters, particularly quality of life, using data from a national registry. Patients with PsA meeting ClASsification criteria for Psoriatic Arthritis (CASPAR) were enrolled by means of a multi-centre Turkish League Against Rheumatism (TLAR) Network Project. The following information was recorded in web-based case report forms: demographic, clinical and radiographic data; physical examination findings, including tender and swollen joint counts (TJC and SJC); nail and skin involvement; Disease Activity Score-28 for Rheumatoid Arthritis with Erythrocyte Sedimentation Rate (DAS 28-ESR); Bath Ankylosing Spondylitis Disease Activity Index (BASDAI); Maastricht Ankylosing Spondylitis Enthesitis Score (MASES); Psoriasis Area Severity Index (PASI); Bath Ankylosing Spondylitis Radiology Index for the spine (BASRI-s); Health Assessment Questionnaire (HAQ); Bath Ankylosing Spondylitis Functional Index (BASFI); Health Assessment Questionnaire for the spondyloarthropathies (HAQ-s); Psoriatic arthritis quality of Life scale (PsAQoL); Short Form 36 (SF-36); Hospital Anxiety Depression Scale (HADS); Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F); and Fibromyalgia Rapid Screening Tool (FiRST) scores. The patients were divided into two groups, namely with and without enthesitis, based on the triple Likert-type physician-reported statement of ‘active enthesitis’, ‘history of enthesitis’ or ‘none’ in the case report forms. Patients with active enthesitis were compared to others in terms of these clinical parameters. A total of 1130 patients were enrolled in this observational study. Of these patients, 251 (22.2%) had active enthesitis according to the clinical assessment. TJC, HAQ-s, BASDAI, FiRST and PsAQoL were significantly higher whereas the SF-36 scores were lower in patients with enthesitis (p < 0.05). Chronic back pain, dactylitis, and tenosynovitis were more frequent in the enthesopathy group (59.4%/39%, 13.1%/6.5% and 24.7%/3.4%, respectively). Significant positive correlations between the MASES score and the TJC, HAQ, DAS 28-ESR, BASDAI, FiRST and PsAQoL scores, and a negative correlation with the SF-36 score were found. When linear regression analysis was performed, the SF-36 MCS and PCS scores decreased by − 9.740 and − 11.795 units, and the FiRST scores increased by 1.223 units in patients with enthesitis. Enthesitis is an important involvement of PsA with significant relations to quality of life determined with PsAQoL and SF-36 scores. Our study found higher frequency of dactylitis and chronic back pain, and worse quality of life determined with SF-36 and PsAQoL scores in patients with enthesitis.
Yazarlar (37)
1
İsmihan Sunar
ORCID: 0000-0002-4435-5677
2
Şebnem Ataman
ORCID: 0000-0003-3570-3825
3
Kemal Nas
ORCID: 0000-0002-5845-0851
4
Erkan Kılıç
ORCID: 0000-0003-4355-4356
5
Betül Sargın
ORCID: 0000-0002-9463-8413
6
Sevtap Acer Kasman
ORCID: 0000-0002-4805-0555
7
Hakan Alkan
ORCID: 0000-0001-8461-9131
8
Nilay Şahin
ORCID: 0000-0001-6062-6935
9
Gizem Cengiz
ORCID: 0000-0002-8143-3048
10
Nihan Cüzdan
ORCID: 0000-0001-7238-657X
11
Ilknur Albayrak Gezer
ORCID: 0000-0002-8980-1837
12
Dilek Keskin
ORCID: 0000-0001-5300-6391
13
Cevriye Mülkoğlu
ORCID: 0000-0001-9113-3885
14
Hatice Reşorlu
ORCID: 0000-0001-9889-1064
15
Ajda Bal
ORCID: 0000-0002-3910-2851
16
Mehmet Tuncay Duruöz
ORCID: 0000-0003-3584-2788
17
Okan Küçükakkaş
ORCID: 0000-0001-6971-4229
18
Ozan Volkan Yurdakul
ORCID: 0000-0003-4567-8133
19
Meltem Alkan Melikoğlu
ORCID: 0000-0001-7519-9470
20
Yıldıray Aydın
ORCID: 0000-0003-4299-5627
21
Fikriye Figen Ayhan
ORCID: 0000-0001-6906-991X
22
Hatice Bodur
ORCID: 0000-0003-3008-7007
23
Mustafa Çalış
ORCID: 0000-0002-1184-0772
24
Erhan Capkin
ORCID: 0000-0003-2728-5934
25
Gül Devrimsel
ORCID: 0000-0001-9775-6426
26
Kevser Gok
ORCID: 0000-0001-8639-751X
27
Sami Hizmetli
ORCID: 0000-0002-0418-0155
28
Ayhan Kamanlı
ORCID: 0000-0001-5299-7250
29
Yaşar Keskin
ORCID: 0000-0003-4457-5917
30
Hilal Kocabaş
ORCID: 0000-0001-9274-168X
31
Öznur Kutluk
ORCID: 0000-0003-1037-7381
32
Nesrin Şen
ORCID: 0000-0003-0966-0075
33
Ömer Faruk Şendur
ORCID: 0000-0002-0718-9438
34
İbrahim Tekeoğlu
ORCID: 0000-0003-3395-7178
35
Sena Tolu
ORCID: 0000-0002-1111-3110
36
Murat Toprak
ORCID: 0000-0002-6490-4645
37
Tiraje Tuncer
ORCID: 0000-0001-8654-0603
Anahtar Kelimeler
Disease activity
Enthesitis
Enthesopathy
Psoriatic arthritis
Quality of life
Registry
Kurumlar
Afyonkarahisar State Hospital
Afyonkarahisar Turkey
Akdeniz Üniversitesi
Antalya Turkey
Ankara Numune Education and Research Hospital
Ankara Turkey
Ankara Üniversitesi
Ankara Turkey
Ankara Yildirim Beyazit University
Ankara Turkey
Atatürk Üniversitesi
Erzurum Turkey
Aydin Adnan Menderes University
Aydin Turkey
Balikesir Üniversitesi
Balikesir Turkey
Bezmialem Foundation University
Istanbul Türkiye
Çanakkale Onsekiz Mart Üniversitesi
Canakkale Turkey
Cumhuriyet Üniversitesi Tip Fakültesi
Sivas Turkey
Erciyes University, Faculty of Medicine
Kayseri Turkey
İstanbul Medipol Üniversitesi
Istanbul Turkey
Karadeniz Technical University
Trabzon Turkey
Kartal Dr. Lutfi Kirdar Training and Research Hospital
Istanbul Turkey
Kirikkale Üniversitesi
Kirikkale Turkey
Marmara Üniversitesi Tip Fakültesi
Istanbul Turkey
Necmettin Erbakan Üniversitesi
Meram Turkey
Pamukkale Üniversitesi Tip Fakültesi
Denizli Turkey
Recep Tayyip Erdogan University
Rize Turkey
Sakarya Üniversitesi
Serdivan Turkey
Sanliurfa Training and Research Hospital
Sanliurfa Turkey
Selçuk Üniversitesi
Selçuklu Turkey
T. C. Sağlık Bakanlığı Ankara Diskapi Yildirim Beyazit Eğitim ve Araştirma Hastanesi
Ankara Turkey
Usak University
Usak Turkey
Van Training and Research Hospital
Van Türkiye
Van Yüzüncü Yıl Üniversitesi
Van Turkey
Metrikler
29
Atıf
37
Yazar
6
Anahtar Kelime