Scopus
YÖKSİS Eşleşti
The impact of fatigue on patients with psoriatic arthritis: a multi-center study of the TLAR-network
Rheumatology International · Kasım 2020
YÖKSİS Kayıtları
The impact of fatigue on patients with psoriatic arthritis: a multi-center study of the TLAR-network
Rheumatology International · 2020 SCI-Expanded
PROFESÖR İLKNUR ALBAYRAK GEZER →
Makale Bilgileri
DergiRheumatology International
Yayın TarihiKasım 2020
Cilt / Sayfa40 · 1803-1815
Scopus ID2-s2.0-85086788470
Özet
Fatigue is a substantial problem in patients with psoriatic arthritis (PsA) that needs to be considered in the core set of domains. This study aimed to evaluate fatigue and its relationship with disease parameters, functional disability, anxiety, depression, quality of life, and correlation with disease activity as determined by various scales. A total of 1028 patients (677 females, 351 males) with PsA who met the CASPAR criteria were included [Turkish League Against Rheumatism (TLAR) Network multicenter study]. The demographic features and clinical conditions of the patients were recorded. Correlations between fatigue score and clinical parameters were evaluated using the Disease Activity Score 28 (DAS28), Disease Activity in Psoriatic Arthritis (DAPSA), Clinical DAPSA (cDAPSA), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), the Fibromyalgia Rapid Screening Tool (FiRST), minimal disease activity (MDA), and very low disease activity (VLDA). Fatigue was assessed with the Functional Assessment of Chronic Illness Therapy (FACIT-F) and a 10-point VAS (VAS-F). The mean age of the patients was 47 (SD: 12.2) years, and the mean disease duration was 6.4 (SD: 7.3) years. The mean VAS-F score was 5.1 (SD: 2.7), with fatigue being absent or mild, moderate, and severe in 12.8%, 24.6%, and 62.5% of the patients, respectively. Fatigue scores were significantly better in patients with DAS28 remission, DAPSA remission, cDAPSA remission, MDA, and VLDA (p < 0.001). Fatigue scores significantly increased with increasing disease activity levels on the DAS28, DAPSA, and cDAPSA (p < 0.001). VAS-F scores showed correlations with the scores of the BASDAI, BASFI, PsAQoL, HAD-A, FiRST, pain VAS, and PtGA. FiRST scores showed fibromyalgia in 255 (24.8%) patients. FACIT-F and VAS-F scores were significantly higher in patients with fibromyalgia (p < 0.001). In regression analysis, VLDA, BASDAI score, FiRST score, high education level, HAD-Anxiety, and BMI showed independent associations with fatigue. Our findings showed that fatigue was a common symptom in PsA and disease activity was the most substantial predictor, with fatigue being less in patients in remission, MDA, and VLDA. Other correlates of fatigue were female gender, educational level, anxiety, quality of life, function, pain, and fibromyalgia.
Yazarlar (37)
1
Mehmet Tuncay Duruöz
ORCID: 0000-0003-3584-2788
2
Halise Hande Gezer
ORCID: 0000-0001-8790-304X
3
Kemal Nas
ORCID: 0000-0002-5845-0851
4
Erkan Kılıç
ORCID: 0000-0003-4355-4356
5
Betül Sargın
ORCID: 0000-0002-9463-8413
6
Sevtap Acer Kasman
ORCID: 0000-0002-4805-0555
7
Hakan Alkan
ORCID: 0000-0001-8461-9131
8
Nilay Şahin
ORCID: 0000-0001-6062-6935
9
Gizem Cengiz
ORCID: 0000-0002-8143-3048
10
Nihan Cüzdan
ORCID: 0000-0001-7238-657X
11
Ilknur Albayrak Gezer
12
Dilek Keskin
ORCID: 0000-0001-5300-6391
13
Cevriye Mülkoğlu
ORCID: 0000-0001-9113-3885
14
Hatice Reşorlu
ORCID: 0000-0001-9889-1064
15
Şebnem Ataman
ORCID: 0000-0003-3570-3825
16
Ajda Bal
ORCID: 0000-0002-3910-2851
17
Okan Küçükakkaş
ORCID: 0000-0001-6971-4229
18
Ozan Volkan Yurdakul
ORCID: 0000-0003-4567-8133
19
Meltem Alkan Melikoğlu
ORCID: 0000-0001-7519-9470
20
Fikriye Figen Ayhan
ORCID: 0000-0001-6906-991X
21
Merve Baykul
ORCID: 0000-0003-0434-396X
22
Hatice Bodur
ORCID: 0000-0003-3008-7007
23
Mustafa Çalış
ORCID: 0000-0002-1184-0772
24
Erhan Capkin
ORCID: 0000-0003-2728-5934
25
Gül Devrimsel
ORCID: 0000-0001-9775-6426
26
Kevser Gok
ORCID: 0000-0001-8639-751X
27
Sami Hizmetli
ORCID: 0000-0002-0418-0155
28
Ayhan Kamanlı
ORCID: 0000-0001-5299-7250
29
Yaşar Keskin
ORCID: 0000-0003-4457-5917
30
Hilal Ecesoy
ORCID: 0000-0001-9274-168X
31
Öznur Kutluk
ORCID: 0000-0003-1037-7381
32
Nesrin Şen
ORCID: 0000-0003-0966-0075
33
Ömer Faruk Şendur
ORCID: 0000-0002-0718-9438
34
İbrahim Tekeoğlu
ORCID: 0000-0003-3395-7178
35
Sena Tolu
ORCID: 0000-0002-1111-3110
36
Murat Toprak
ORCID: 0000-0002-6490-4645
37
Tiraje Tuncer
ORCID: 0000-0001-8654-0603
Anahtar Kelimeler
Disease activity
Fatigue
Lassitude
Outcome measure
Psoriatic arthritis
Kurumlar
Akdeniz Üniversitesi
Antalya Turkey
Ankara City Hospital
Ankara Turkey
Ankara Numune Education and Research Hospital
Ankara Turkey
Ankara Üniversitesi
Ankara Turkey
Ankara Yildirim Beyazit University
Ankara Turkey
Atatürk Üniversitesi
Erzurum Turkey
Aydin Adnan Menderes University
Aydin Turkey
Balikesir Üniversitesi
Balikesir Turkey
Bezmialem Foundation University
Istanbul Türkiye
Çanakkale Onsekiz Mart Üniversitesi
Canakkale Turkey
Cumhuriyet Üniversitesi Tip Fakültesi
Sivas Turkey
Erciyes University, Faculty of Medicine
Kayseri Turkey
İstanbul Medipol Üniversitesi
Istanbul Turkey
Kanuni Training and Research Hospital
Trabzon Turkey
Karadeniz Technical University
Trabzon Turkey
Kartal Dr. Lütfi Kırdar City Hospital
Istanbul Türkiye
Kirikkale Üniversitesi
Kirikkale Turkey
Marmara Üniversitesi Tip Fakültesi
Istanbul Turkey
Necmettin Erbakan Üniversitesi
Meram Turkey
Pamukkale Üniversitesi Tip Fakültesi
Denizli Turkey
Recep Tayyip Erdogan University
Rize Turkey
Sakarya Üniversitesi
Serdivan Turkey
Sanliurfa Training and Research Hospital
Sanliurfa Turkey
Selçuk Üniversitesi
Selçuklu Turkey
University of Health Sciences
Istanbul Turkey
Usak University
Usak Turkey
Van Training and Research Hospital
Van Türkiye
Van Yüzüncü Yıl Üniversitesi
Van Turkey
Metrikler
13
Atıf
37
Yazar
5
Anahtar Kelime