Scopus
The effect of gender on disease activity and clinical characteristics in patients with axial psoriatic arthritis
Modern Rheumatology · Ocak 2021
Makale Bilgileri
DergiModern Rheumatology
Yayın TarihiOcak 2021
Cilt / Sayfa31 · 869-874
Scopus ID2-s2.0-85091045265
Özet
Objectives: In this study, we aimed to evaluate the effect of gender on clinical findings, disease activity, functional status and quality of life in patients with axial involvement in Turkey. Methods: Patients with PsA who met the CASPAR classification criteria were enrolled consequently in this cohort. Turkish League Against Rheumatism (TLAR)-Network was formed with the participation of 25 centres. The demographic variables, fatigue, diagnostic delay, the beginning of peripheral arthritis, enthesitis, dactylitis and spine involvement, inflammatory low back pain, BASFI, HAQ, HAQ-s, visual analogue scale-pain (VAS-pain), anxiety, depression and disease activity parameters (ESR, DAS28, BASDAI) were recorded. Axial involvement was assessed according to clinical and radiological data according to modified New York (MNYC) or Assessment of SpondyloArthritis international Society (ASAS) criteria. Results: A total of 1018 patients with PsA were included in this study. Of the 373 patients with axial involvement, 150 were male (40.2%) and 223 (59.8%) were female. Spondylitis was detected in 14,7% of men and 21,9% of women in all patients. Pain score (VAS) (p <.002), fatigue (p <.001), ESR (p <.001), DAS28 (p <.001), BASDAI score (p <.001), PsAQoL (p <.001), HAQ score (p <,01), HAQ-S score (p <.001), anxiety (p <.001), depression (p <.024), FACIT (p <.001) and FiRST (p <.001) scores were statistically significantly worse in women than males with axial PsA. However, quality of life was better (p <.001) and PASI score (p <.005) were statistically worse in male patients than in female patients with axial involvement. Conclusion: This study has shown that the burden of disease in axial PsA has significant difference between genders. Disease activity, physical disability, functional limitation, depression and anxiety scores were higher in female patients, while quality of life were better and PASI score were higher in male patients. Therefore, we suggest that new strategies should be developed for more effective treatment of axial PsA in female patients.
Yazarlar (37)
1
Kemal Nas
ORCID: 0000-0002-5845-0851
2
Erkan Kılıç
ORCID: 0000-0003-4355-4356
3
İbrahim Tekeoğlu
ORCID: 0000-0003-3395-7178
4
Yaşar Keskin
ORCID: 0000-0003-4457-5917
5
Remzi Çevik
ORCID: 0000-0002-4124-1586
6
Betül Sargın
ORCID: 0000-0002-9463-8413
7
Sevtap Acer Kasman
ORCID: 0000-0002-4805-0555
8
Hakan Alkan
ORCID: 0000-0001-8461-9131
9
Nilay Şahin
ORCID: 0000-0001-6062-6935
10
Gizem Cengiz
ORCID: 0000-0002-8143-3048
11
Nihan Cüzdan
ORCID: 0000-0001-7238-657X
12
Ilknur Albayrak Gezer
13
Dilek Keskin
ORCID: 0000-0001-5300-6391
14
Cevriye Mülkoğlu
ORCID: 0000-0001-9113-3885
15
Hatice Reşorlu
ORCID: 0000-0001-9889-1064
16
Şebnem Ataman
ORCID: 0000-0003-3570-3825
17
Ajda Bal
ORCID: 0000-0002-3910-2851
18
Merve Baykul
ORCID: 0000-0003-0434-396X
19
Mehmet Tuncay Duruöz
ORCID: 0000-0003-3584-2788
20
Okan Küçükakkaş
ORCID: 0000-0001-6971-4229
21
Ozan Volkan Yurdakul
ORCID: 0000-0003-4567-8133
22
Meltem Alkan Melikoğlu
ORCID: 0000-0001-7519-9470
23
Fikriye Figen Ayhan
ORCID: 0000-0001-6906-991X
24
Hatice Bodur
ORCID: 0000-0003-3008-7007
25
Mustafa Çalış
ORCID: 0000-0002-1184-0772
26
Erhan Capkin
ORCID: 0000-0003-2728-5934
27
Gül Devrimsel
ORCID: 0000-0001-9775-6426
28
Kevser Gok
ORCID: 0000-0001-8639-751X
29
Sami Hizmetli
ORCID: 0000-0002-0418-0155
30
Ayhan Kamanlı
ORCID: 0000-0001-5299-7250
31
Hilal Kocabaş
ORCID: 0000-0001-9274-168X
32
Öznur Kutluk
ORCID: 0000-0003-1037-7381
33
Nesrin Şen
ORCID: 0000-0003-0966-0075
34
Ömer Faruk Şendur
ORCID: 0000-0002-0718-9438
35
Murat Toprak
ORCID: 0000-0002-6490-4645
36
Sena Tolu
ORCID: 0000-0002-1111-3110
37
Tiraje Tuncer
ORCID: 0000-0001-8654-0603
Anahtar Kelimeler
axial involvement
gender
Psoriatic arthritis
quality of life
risk factors
Kurumlar
Akdeniz Üniversitesi
Antalya Turkey
Ankara City Hospital
Ankara Turkey
Ankara Numune Education and Research Hospital
Ankara Turkey
Ankara Üniversitesi
Ankara Turkey
Ankara Yildirim Beyazit University
Ankara Turkey
Atatürk Üniversitesi
Erzurum Turkey
Atilim University
Ankara Turkey
Aydin Adnan Menderes University
Aydin Turkey
Balikesir Üniversitesi
Balikesir Turkey
Balıkesir Atatürk City Hospital
Balikesir Turkey
Bezmialem Foundation University
Istanbul Türkiye
Çanakkale Onsekiz Mart Üniversitesi
Canakkale Turkey
Cumhuriyet Üniversitesi Tip Fakültesi
Sivas Turkey
Dicle University, Faculty of Medicine
Diyarbakir Turkey
Dr. Lutfi Kirdar Kartal Training and Research Hospital
Istanbul Turkey
Erciyes University, Faculty of Medicine
Kayseri Turkey
İstanbul Medipol Üniversitesi
Istanbul Turkey
Kanuni Training and Research Hospital
Trabzon Turkey
Karadeniz Technical University
Trabzon Turkey
Kirikkale Üniversitesi
Kirikkale Turkey
Marmara Üniversitesi Tip Fakültesi
Istanbul Turkey
Necmettin Erbakan Üniversitesi
Meram Turkey
Pamukkale Üniversitesi Tip Fakültesi
Denizli Turkey
Recep Tayyip Erdogan University
Rize Turkey
Sakarya Üniversitesi
Serdivan Turkey
Selçuk Üniversitesi
Selçuklu Turkey
University of Health Sciences
Istanbul Turkey
Van Yüzüncü Yıl Üniversitesi
Van Turkey
Metrikler
17
Atıf
37
Yazar
5
Anahtar Kelime