Scopus
Impact of obesity on quality of life, psychological status, and disease activity in psoriatic arthritis: a multi‑center study
Rheumatology International · Nisan 2022
Makale Bilgileri
DergiRheumatology International
Yayın TarihiNisan 2022
Cilt / Sayfa42 · 659-668
Scopus ID2-s2.0-85113804909
Özet
This article aims to evaluate the possible effect of obesity on quality of life, psychological status, and other clinical variables in Psoriatic arthritis (PsA). PsA patients have been recruited by the Turkish League Against Rheumatism-Network from various centers in Turkey in this cross-sectional study. Patients with a body mass index (BMI) ≥ of 30 kg/m2 were considered obese. Differences among patients with regard to obesity status were assessed with health-related quality of life measures (PsA Quality of Life Questionnaire [PsAQoL]), psychological status (Hospital Anxiety and Depression Scale [HADS]), and disease activity parameters (the Disease Activity index for PSoriatic Arthritis [DAPSA], Disease Activity Score 28-C-reactive protein [DAS28-CRP], Bath Ankylosing Spondylitis Disease Activity Index [BASDAI], Psoriasis Area and Severity Index [PASI]), physical functions (Ankylosing Spondylitis Functional Index [BASFI], Health Assessment Questionnaire [HAQ], and Health Assessment Questionnaire for the spondyloarthropathies [HAQ-S]). Pain was assessed using visual analog scale of pain (VAS-P), and fatigue was evaluated using visual analog scale of fatigue (VAS-F) and Functional Assessment of Chronic Illness Therapy (FACIT). A total of 1033 patients with PsA, 650 (62.9%) non-obese and 383 (37.1%) obese were included in the study. The PsAQoL, HADS-Anxiety, HADS-Depression, DAPSA, DAS28-CRP, BASDAI, BASFI, HAQ and HAQ-S scores of the obese group were higher than the non-obese group (p < 0.05). VAS-P and PASI scores were similar between group of patients with and without obesity. Obese patients had higher median scores of VAS-F and FACIT than non-obese patients (p < 0.05). Linear regression analysis showed that BMI affects the quality of life, depression, and disease activity. Consequently, obesity has significant associations with higher disease activity, lower QoL, risk of anxiety, depression, and fatigue. Therefore, obesity should also be taken into account in the management of PsA patients.
Yazarlar (36)
1
Kevser Gok
ORCID: 0000-0001-8639-751X
2
Kemal Nas
ORCID: 0000-0002-5845-0851
3
İbrahim Tekeoğlu
ORCID: 0000-0003-3395-7178
4
İsmihan Sunar
ORCID: 0000-0002-4435-5677
5
Yaşar Keskin
ORCID: 0000-0003-4457-5917
6
Erkan Kılıç
ORCID: 0000-0003-4355-4356
7
Betül Sargın
ORCID: 0000-0002-9463-8413
8
Sevtap Acer Kasman
ORCID: 0000-0002-4805-0555
9
Hakan Alkan
ORCID: 0000-0001-8461-9131
10
Nilay Şahin
ORCID: 0000-0001-6062-6935
11
Gizem Cengiz
ORCID: 0000-0002-8143-3048
12
Nihan Cüzdan
ORCID: 0000-0001-7238-657X
13
Ilknur Albayrak Gezer
14
Dilek Keskin
ORCID: 0000-0001-5300-6391
15
Cevriye Mülkoğlu
ORCID: 0000-0001-9113-3885
16
Hatice Reşorlu
ORCID: 0000-0001-9889-1064
17
Ajda Bal
ORCID: 0000-0002-3910-2851
18
Mehmet Tuncay Duruöz
ORCID: 0000-0003-3584-2788
19
Okan Küçükakkaş
ORCID: 0000-0001-6971-4229
20
Ozan Volkan Yurdakul
ORCID: 0000-0003-4567-8133
21
Meltem Alkan Melikoğlu
ORCID: 0000-0001-7519-9470
22
Yıldıray Aydın
ORCID: 0000-0003-4299-5627
23
Fikriye Figen Ayhan
ORCID: 0000-0001-6906-991X
24
Hatice Bodur
ORCID: 0000-0003-3008-7007
25
Mustafa Çalış
ORCID: 0000-0002-1184-0772
26
Erhan Capkin
ORCID: 0000-0003-2728-5934
27
Gül Devrimsel
ORCID: 0000-0001-9775-6426
28
Hilal Ecesoy
ORCID: 0000-0001-9274-168X
29
Sami Hizmetli
ORCID: 0000-0002-0418-0155
30
Ayhan Kamanlı
ORCID: 0000-0001-5299-7250
31
Öznur Kutluk
ORCID: 0000-0003-1037-7381
32
Nesrin Şen
ORCID: 0000-0003-0966-0075
33
Ömer Faruk Şendur
ORCID: 0000-0002-0718-9438
34
Sena Tolu
ORCID: 0000-0002-1111-3110
35
Murat Toprak
ORCID: 0000-0002-6490-4645
36
Tiraje Tuncer
ORCID: 0000-0001-8654-0603
Anahtar Kelimeler
Anxiety
Depression
Disease activity
Obesity
Psoriatic arthritis
Quality of life
Kurumlar
Akdeniz Üniversitesi
Antalya Turkey
Ankara City Hospital
Ankara Turkey
Ankara Numune Education and Research Hospital
Ankara Turkey
Ankara Yildirim Beyazit University
Ankara Turkey
Antalya Training and Research Hospital
Antalya Turkey
Atatürk Üniversitesi
Erzurum Turkey
Atilim University
Ankara Turkey
Aydin Adnan Menderes University
Aydin Turkey
Aydin State Hospital
Aydin Turkey
Balikesir Üniversitesi
Balikesir Turkey
Balıkesir Atatürk City Hospital
Balikesir Turkey
Bezmiâlem Vakıf Üniversitesi
Istanbul Turkey
Çanakkale Onsekiz Mart Üniversitesi
Canakkale Turkey
Cumhuriyet Üniversitesi Tip Fakültesi
Sivas Turkey
Dr. Lutfi Kirdar Kartal Training and Research Hospital
Istanbul Turkey
Erciyes University, Faculty of Medicine
Kayseri Turkey
İstanbul Medipol Üniversitesi
Istanbul Turkey
Kanuni Training and Research Hospital
Trabzon Turkey
Kapaklı State Hospital
Tekirdag Turkey
Karadeniz Technical University
Trabzon Turkey
Kirikkale Üniversitesi
Kirikkale Turkey
Klinik FTR
Istanbul Turkey
Marmara Üniversitesi Tip Fakültesi
Istanbul Turkey
Necmettin Erbakan Üniversitesi
Meram Turkey
Pamukkale Üniversitesi Tip Fakültesi
Denizli Turkey
Recep Tayyip Erdogan University
Rize Turkey
Sakarya Üniversitesi
Serdivan Turkey
Selçuk Üniversitesi
Selçuklu Turkey
T. C. Sağlık Bakanlığı Ankara Diskapi Yildirim Beyazit Eğitim ve Araştirma Hastanesi
Ankara Turkey
Van Yüzüncü Yıl Üniversitesi
Van Turkey
Metrikler
12
Atıf
36
Yazar
6
Anahtar Kelime