Scopus
🔓 Açık Erişim
Regional variations in psoriatic arthritis: Insights from a nationwide multicenter analysis in Türkiye
Archives of Rheumatology · Eylül 2024
Makale Bilgileri
DergiArchives of Rheumatology
Yayın TarihiEylül 2024
Cilt / Sayfa39 · 339-349
Scopus ID2-s2.0-85203023813
Erişim🔓 Açık Erişim
Özet
Objectives: The study aimed to investigate and compare clinical features, disease activity, and the overall disease burden among psoriatic arthritis (PsA) patients across seven distinct geographic regions in Türkiye. Patients and methods: A multicenter cross-sectional study involving 1,134 PsA patients from 25 referral centers across seven regions was conducted. Demographic and clinical characteristics, comorbidities, joint involvement, extra-articular manifestations, and disease activity measures were evaluated across regions. Results: A total of 1134 PsA patients from seven different geographic regions in Türkiye participated in this study. The highest number of participants was from the Marmara region (n=409), with subsequent representation from Central Anatolia (n=370), Aegean (n=139), Mediterranean (n=60), Black Sea (n=60), Eastern Anatolia (n=60), and Southeastern Anatolia (n=36) regions. There were significant variations in demographic profile, including age, body mass index, age of disease onset, educational status, comorbidities, and family history of both psoriasis and PsA. Clinical features, such as enthesitis, dactylitis, uveitis, and joint involvement, demonstrated significant variation across regions. Additionally, disease activity measures, including pain, patient and physician global assessments, acute phase reactants, disease activity indices, quality of life, and functional status, displayed considerable regional differences. Conclusion: This nationwide study revealed substantial regional diversity in demographic data, clinical characteristics, disease activity, and quality of life among PsA patients in Türkiye. These findings stress the need to customize treatment approaches to address regional needs and to conduct further research to uncover reasons for disparities. It is crucial to enhance region-specific approaches to improve patient care and outcomes for PsA.
Yazarlar (37)
1
Erkan Kılıç
ORCID: 0000-0003-4355-4356
2
Gamze Kılıç
ORCID: 0000-0003-1998-0988
3
İbrahim Tekeoğlu
ORCID: 0000-0003-3395-7178
4
Betül Sargın
ORCID: 0000-0002-9463-8413
5
Sevtap Acer Kasman
ORCID: 0000-0002-4805-0555
6
Hakan Alkan
ORCID: 0000-0001-8461-9131
7
Nilay Şahin
ORCID: 0000-0001-6062-6935
8
Gizem Cengiz
ORCID: 0000-0002-8143-3048
9
Nihan Cüzdan
ORCID: 0000-0001-7238-657X
10
Ilknur Albayrak Gezer
ORCID: 0000-0002-8980-1837
11
Dilek Keskin
ORCID: 0000-0001-5300-6391
12
Cevriye Mülkoğlu
ORCID: 0000-0001-9113-3885
13
Hatice Reşorlu
ORCID: 0000-0001-9889-1064
14
İsmihan Sunar
ORCID: 0000-0002-4435-5677
15
Ajda Bal
ORCID: 0000-0002-3910-2851
16
Mehmet Tuncay Duruöz
ORCID: 0000-0003-3584-2788
17
Okan Küçükakkaş
ORCID: 0000-0001-6971-4229
18
Ozan Volkan Yurdakul
ORCID: 0000-0003-4567-8133
19
Meltem Alkan Melikoğlu
ORCID: 0000-0001-7519-9470
20
Yıldıray Aydın
ORCID: 0000-0003-4299-5627
21
Fikriye Figen Ayhan
ORCID: 0000-0001-6906-991X
22
Hatice Bodur
ORCID: 0000-0003-3008-7007
23
Mustafa Çalış
ORCID: 0000-0002-1184-0772
24
Erhan Capkin
ORCID: 0000-0003-2728-5934
25
Gül Devrimsel
ORCID: 0000-0001-9775-6426
26
Kevser Orhan
ORCID: 0000-0001-8639-751X
27
Sami Hizmetli
ORCID: 0000-0002-0418-0155
28
Ayhan Kamanlı
ORCID: 0000-0001-5299-7250
29
Yaşar Keskin
ORCID: 0000-0003-4457-5917
30
Hilal Ecesoy
ORCID: 0000-0001-9274-168X
31
Öznur Kutluk
ORCID: 0000-0003-1037-7381
32
Nesrin Şen
ORCID: 0000-0003-0966-0075
33
Ömer Faruk Şendur
ORCID: 0000-0002-0718-9438
34
Sena Tolu
ORCID: 0000-0002-1111-3110
35
Murat Toprak
ORCID: 0000-0002-6490-4645
36
Tiraje Tuncer
ORCID: 0000-0001-8654-0603
37
Kemal Nas
ORCID: 0000-0002-5845-0851
Anahtar Kelimeler
Arthritis
differences
geographic locations
psoriatic
regional
spondyloarthritis
Kurumlar
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