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Preparation, characterization and antimicrobial activity of sodium carboxymethyl cellulose - based hydrogels by freeze-thaw method

Journal of Thermoplastic Composite Materials · Ocak 2025

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YÖKSİS Kayıtları
Preparation, characterization and antimicrobial activity of sodium carboxymethyl cellulose - based hydrogels by freeze-thaw method
Journal of Thermoplastic Composite Materials · 2025 SCI-Expanded
PROFESÖR AHMET UYSAL →
Preparation, characterization and antimicrobial activity of sodium carboxymethyl cellulose - based hydrogels by freeze-thaw method
Journal of Thermoplastic Composite Materials · 2025 SCI-Expanded
PROFESÖR AHMET OKUDAN →

Makale Bilgileri

DergiJournal of Thermoplastic Composite Materials
Yayın TarihiOcak 2025
DOI10.1177/08927057251314437
Scopus ID2-s2.0-85216179097
Özet This study evaluated the structural and functional properties of poly (vinyl alcohol)/sodium carboxymethyl cellulose (PVA/NaCMC) hydrogels synthesized via the freeze-thawing method using 1% acetic acid (AAc) and distilled water (Dw) as solvents. The results demonstrate that solvent choice and NaCMC concentration significantly influence hydrogel performance, particularly for wound dressings. PVA/NaCMC (AAc)-3.5% emerged as the optimal formulation, exhibiting superior antimicrobial activity, structural stability, and enhanced crosslinking, as evidenced by FT-IR, SEM, and TEM analyses. XRD confirmed higher crystallinity in the AAc-based hydrogel, while swelling tests showed greater water absorption in the Dw-based hydrogel, attributed to its looser network. Antimicrobial tests highlighted the broad-spectrum efficacy of PVA/NaCMC (AAc)-3.5%, inhibiting Gram-positive and Gram-negative bacteria and fungi due to acetic acid’s low pH and hydrogen bond stabilization. These findings emphasize the importance of solvent selection in designing hydrogels for wound care applications requiring infection prevention and structural integrity.

Yazarlar (5)

1
Seyda Bayraktar
ORCID: 0000-0003-0429-9604
2
Buse Copur
ORCID: 0000-0002-0096-9300
3
Erdogan Gunes
4
Ahmet Uysal
5
Ahmet Okudan

Anahtar Kelimeler

acetic acid antimicrobial activity poly (vinyl alcohol) skin adhesion Sodium carboxymethyl cellulose (NaCMC)

Kurumlar

Selçuk Üniversitesi
Selçuklu Turkey

Metrikler

1
Atıf
5
Yazar
5
Anahtar Kelime

Sistemimizdeki Yazarlar

AO
AHMET OKUDAN
PROFESÖR

Hızlı Erişim

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