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Retinal and choroidal vascular changes in newly diagnosed celiac disease: An optical coherence tomography angiography study

Indian Journal of Ophthalmology · Mart 2022

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YÖKSİS Kayıtları
Retinal and choroidal vascular changes in newly diagnosed celiac disease: An optical coherence tomography angiography study
Medknow · 2022 SCI-Expanded
PROFESÖR HALİL HALDUN EMİROĞLU →
Retinal and choroidal vascular changes in newly diagnosed celiac disease: An optical coherence tomography angiography study
Indian Journal of Ophthalmology · 2022 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ MELTEM GÜMÜŞ →
Retinal and choroidal vascular changes in newly diagnosed celiac disease: An optical coherence tomography angiography study
Indian Journal of Ophthalmology · 2022 SCI-Expanded
PROFESÖR HALİL HALDUN EMİROĞLU →

Makale Bilgileri

DergiIndian Journal of Ophthalmology
Yayın TarihiMart 2022
Cilt / Sayfa70 · 866-871
Erişim🔓 Açık Erişim
Özet Purpose: To investigate the retinal and choroidal microcirculation changes in celiac disease (CD) patients via optical coherence tomography angiography (OCT-A). Methods: This cross-sectional study included 44 pediatric patients with newly diagnosed CD and 44 healthy pediatric subjects. The vascular densities (VD) of the superficial, deep, and choriocapillar plexuses (VDs, VDd, and VDcc, respectively) (%), the superficial and deep foveal avascular zones (FAZs and FAZd) (%), the central macular thickness (CMT) (μm), and the subfoveal choroidal thickness (SFCT) (μm) were measured with swept-source OCT-A in addition to a complete ophthalmological examination. Results: Mean ages of the CD patients and the healthy participants were 12.02 ± 2.9 and 13.6 ± 2.3 years, respectively. The central sectors of the VDs and VDd measurements were found to be significantly higher in the study group compared to the control group (p = 0.006; P = 0.001, respectively), and the temporal and nasal values of the VDcc measurements were significantly lower in the study group than in the control group (p < 0.05 for both values). CMT and FAZ metrics did not differ between the groups (p > 0.05). SFCT was significantly reduced (p = 0.001), and choroidal thinning was more considerable in female CD patients (p = 0.045). Conclusion: CD seems to affect macular and choroidal microcirculation. The reduced choriocapillaris plexus parameters and choroidal thickness may provide disease activity information.

Yazarlar (5)

1
Meltem Gumus
2
Serhat Eker
ORCID: 0000-0003-4107-7402
3
Yalçın Karaküçük
4
Anna Carina Ergani
5
Halil Haldun Emiroğlu

Anahtar Kelimeler

Celiac disease Choroidal thickness Macular perfusion Retinal vasculature Swept-source optical coherence tomography angiography Vessel density

Kurumlar

Selçuk Tip Fakültesi
Konya Turkey

Metrikler

6
Atıf
5
Yazar
6
Anahtar Kelime