Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Differential Diagnosis of Patients with Total Serum Immunoglobulin E Above 2000 IU/L
Asthma Allergy Immunology · Aralık 2023
YÖKSİS Kayıtları
Differential Diagnosis of Patients with Total Serum Immunoglobulin E Above 2000 IU/L
Asthma Allergy Immunology · 2023 ESCI
DOÇENT İLKNUR KÜLHAŞ ÇELİK →
Makale Bilgileri
DergiAsthma Allergy Immunology
Yayın TarihiAralık 2023
Cilt / Sayfa21 · 207-214
Scopus ID2-s2.0-85181207854
Erişim🔓 Açık Erişim
Özet
Objective: Allergic diseases, infections, parasitic infections, hematologic malignancies, chronic lung diseases, inflammatory diseases, cystic fibrosis, nephrotic syndrome and primary immunodeficiencies (PIDs) are the main disorders in the differential diagnosis of elevated serum IgE levels. The aim of this study was to evaluate the differential clinical diagnosis of patients whose serum IgE levels were found to be above 2000 IU/ml when measured at the pediatric allergy and immunology outpatient clinics of our hospital. Materials and Methods: This was a retrospective study of children aged between 2 months to 18 years referred to the Pediatric Allergy and Immunology clinics and evaluated at our hospital between October 2010 and March 2021. Results: In the 480 patients with serum total IgE levels exceeding 2000 IU/ml in this study, allergic diseases were observed in 313 (65.2%) patients, primary immunodeficiencies in 28 (5.8%), infectious diseases in 12 (2.4%), hematological diseases in 14 (2.8%), rheumatologic diseases in 5 (1%), and other diseases in 2 (0.4%), while 113 (23.5%) patients were undefined. Conclusion: This study revealed that allergic diseases were the most common cause of extremely elevated serum IgE levels, while 5.8% of the patients were diagnosed with primary immunodeficiencies. Our study indicates that primary immunodeficiencies, although rare, should be kept in mind in patients with a serum total IgE above 2000 IU/ml.
Yazarlar (7)
1
Azize Pinar Metbulut
ORCID: 0000-0001-8823-5960
2
Harun Sivlim
ORCID: 0000-0003-3184-5519
3
Ilknur Kulhas Celik
ORCID: 0000-0003-3812-9654
4
Ayse Metin
5
Emine Dibek Misirlioglu
ORCID: 0000-0002-3241-2005
6
Muge Toyran
ORCID: 0000-0002-2490-0551
7
Ersoy Civelek
ORCID: 0000-0002-1780-4801
Anahtar Kelimeler
child
differential diagnosis
Total IgE
Kurumlar
Bayburt State Hospital
Bayburt Turkey
University of Health Sciences
Istanbul Turkey
Metrikler
1
Atıf
7
Yazar
3
Anahtar Kelime