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Comparison of immunogenetic properties of glial tumors with advanced magnetic resonance imaging findings

Turkish Neurosurgery · Ocak 2020

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YÖKSİS Kayıtları
Comparison of Immunogenetic Properties of Glial Tumors with Advanced Magnetic Resonance Imaging Findings
Turkish Neurosurgery · 2020 SCI-Expanded
Doç. Dr. MERT ŞAHİNOĞLU →
Comparison of immunogenetic properties of glial tumors with advanced magnetic resonance imaging findings
Turkish Neurosurgery · 2020 SCI-Expanded
Doç. Dr. BURAK GEZER →
Comparison of immunogenetic properties of glial tumors with advanced magnetic resonance imaging findings
Turkish Neurosurgery · 2020 SCI-Expanded
Prof. Dr. ENDER KÖKTEKİR →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 20 kaydı bulundu.

YÖKSİS Kayıtları — ISSN Eşleşmesi
Solitary metastasis of renal cell carcinoma to the third ventricle mimicking a colloid cyst case report
2015 ISSN: 1019-5149 SCI-Expanded
Prof. Dr. ENDER KÖKTEKİR →
Intracranial Giant Tuberculoma Mimicking Brain Tumor A Case Report
2015 ISSN: 1019-5149 SCI-Expanded
Prof. Dr. ŞUA SÜMER →
Intracranial Giant Tuberculoma Mimicking Brain Tumor A Case Report
2015 ISSN: 1019-5149 SCI-Expanded
Prof. Dr. NAZLIM AKTUĞ DEMİR →
The effect of bevacizumab on spinal epidural fibrosis in a postlaminectomy rat model
2012 ISSN: 1019-5149 SCI-Expanded 4 atıf
Prof. Dr. ENDER KÖKTEKİR →
Intracranial foreing body
2007 ISSN: 1019-5149 SCI-Expanded 5 atıf
Prof. Dr. ENDER KÖKTEKİR →
Characterization of an intracranial neurothekeoma Case report
2010 ISSN: 1019-5149 SCI-Expanded
Prof. Dr. ENDER KÖKTEKİR →
Intracranial giant tuberculoma mimicking brain tumor a case report
2015 ISSN: 1019-5149 SCI-Expanded
Prof. Dr. ENDER KÖKTEKİR →
Endoscopic endonasal transsphenoidal treatment for acromegaly 2010 consensus criteria for remission and predictors of outcomes
2014 ISSN: 1019-5149 SCI-Expanded
Doç. Dr. MERT ŞAHİNOĞLU →
Preliminary experience with squid a new liquid embolizing agent for avm av fistulas and tumors
2014 ISSN: 1019-5149 SCI-Expanded
Doç. Dr. MERT ŞAHİNOĞLU →
Incidence hormonal distribution and postoperative follow up of atypical pituitary adenomas
2013 ISSN: 1019-5149 SCI-Expanded
Doç. Dr. MERT ŞAHİNOĞLU →
Traumatic Acute Subdural Hematomas: Analysis of Outcomes and Predictive Factors at a Single Center
2017 ISSN: 1019-5149 SCI-Expanded
Doç. Dr. MERT ŞAHİNOĞLU →
Vagal nerve stimulation has robust effects on neuropsychiatric assessment in resistant epilepsy: a clinical series with clinical experiences.
2018 ISSN: 1019-5149 SCI-Expanded
Doç. Dr. AHMET HAKAN EKMEKCİ →
The relationship between vasoactive-inotropic score and mortality in the adult patients with traumatic brain injury managed in the intensive care unit
2019 ISSN: 1019-5149 SCI-Expanded
Doç. Dr. MERT ŞAHİNOĞLU →
Comparison of glasgow coma scale and full outline of unresponsiveness (four) score: a prospective study
2019 ISSN: 1019-5149 SCI-Expanded Q4
Doç. Dr. MERT ŞAHİNOĞLU →
Comparison of glasgow coma scale and full outline of unresponsiveness (four) score: a prospective study
2019 ISSN: 1019-5149 SCI-Expanded
Dr. Öğr. Üyesi YEŞİM ŞERİFE BAYRAKTAR →
The relationship between vasoactive-inotropic score and mortality in the adult patients with traumatic brain injury managed in the intensive care unit
2019 ISSN: 1019-5149 SCI-Expanded
Dr. Öğr. Üyesi YEŞİM ŞERİFE BAYRAKTAR →
The relationship between vasoactive-inotropic score and mortality in the adult patients with traumatic brain injury managed in the intensive care unit
2018 ISSN: 1019-5149 SCI-Expanded
Prof. Dr. MEHMET SARGIN →
Comparison of Glasgow Coma Scale and Full Outline ofUnresponsiveness (Four) Score: A Prospective Study
2019 ISSN: 1019-5149 SCI-Expanded Q4
Prof. Dr. FARUK ÇİÇEKCİ →
Comparison of glasgow coma scale and full outline of unresponsiveness (four) score: a prospective study
2019 ISSN: 1019-5149 SCI-Expanded
Prof. Dr. İNCİ KARA →
The relationship between vasoactive-inotropic score and mortality in the adult patients with traumatic brain injury managed in the intensive care unit
2019 ISSN: 1019-5149 SCI-Expanded
Prof. Dr. JALE BENGİ ÇELİK →

Makale Bilgileri

Dergi Turkish Neurosurgery
ISSN10195149
Yayın TarihiOcak 2020
Cilt / Sayfa30 · 422-427
DOI10.5137/1019-5149.JTN.27261-19.3
Scopus ID2-s2.0-85085232373
Erişim🔓 Açık Erişim
Özet AIM: To investigate the immunogenetic properties of glial tumors according to the World Health Organization 2016 glial tumor classification and develop an accurate diagnosis and treatment strategy by comparing preoperative advanced magnetic resonance (aMRI) technique findings of these results. MATERIAL and METHODS: This study was conducted at the Department of Neurosurgery at the Medical Faculty Hospital of Selcuk University between January 1, 2010 and January 4, 2017 and included 50 patients. MR spectroscopy (MRS), MR perfusion (PWI), and MR diffusion (DWI) were performed in 50 patients preoperatively. Patient data were obtained from the hospital's information system. Pathological diagnosis of all patients was taken from the department of pathology at the same medical faculty. RESULTS: Among the patients included in the study, 11 were grade II (22%), 7 were grade III (14%), and 32 were grade IV (64%). All patients were IDH1 stained: 22 were IDH mutant (44%) and 28 were IDH wild-type (56%). A statistically significant difference in the survival time was observed between IDH mutant and wild-type. IDH-mutant tumors were commonly located in the frontal lobe and IDH wild-type tumors in the parietal and temporal lobes. A significant difference in PWI relative cerebral blood volume (rCBV) and DWI apparent diffusion coefficients (ADC) was noted among grade II, III, and IV tumor groups. The PWI rCBV cut-off value for grade IV tumors was 2.05 (90% sensitivity, 78% specificity). No difference in the Cho/Cr ratio among grade II, III, and IV tumor groups was noted. A significant difference was noted between the IDH mutant and wild type in terms of PWI rCBV. The PWI rCBV cut-off value of IDH mutant-wild type was 2.15. No difference in the Cho/Cr, Cho/NAA, and DWI apparent diffusion coefficients (p>0.05) was noted between the IDH mutant and wild type. CONCLUSION: PWI rCBV is the most important prognostic value of aMRI used in tumor grading. PWI rCBV values could be significant in distinguishing IDH wild and mutant.

Yazarlar (6)

1
Burak Gezer
2
Ali Mutlukan
ORCID: 0000-0001-6431-0989
3
Mert Sahinoglu
ORCID: 0000-0003-0633-8304
4
Pınar Karabağlı
ORCID: 0000-0002-5558-0175
5
Ender Koktekir
6
Hakan Karabagli

Anahtar Kelimeler

Isocitratedehydrogenase mutation Magnetic resonance diffusion Magnetic resonance perfusion Magnetic resonance spectroscopy

Kurumlar

Selçuk Üniversitesi
Selçuklu Turkey
Serik State Hospital
Antalya Turkey
Tatvan State Hospital
Bitlis Turkey
Scimago Dergi (ISSN Eşleşmesi)
Turkish Neurosurgery
Q3
SJR Skoru0,330
H-Index39
YayıncıTurkish Neurosurgical Society
ÜlkeTurkey
Neurology (clinical) (Q3)
Surgery (Q3)
Dergi sayfasına git

Metrikler

1
Atıf
6
Yazar
4
Anahtar Kelime

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