Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q3
Clinical Features, Treatment and Outcome of Childhood Glial Tumors
Turkish Neurosurgery · Ocak 2022
YÖKSİS Kayıtları
Clinical features, treatment, and outcome of childhood glial tumors
Turkish Neurosurgical Society · 2022 SCI-Expanded
Doç. Dr. BUKET KARA →
Clinical features, treatment, and outcome of childhood glial tumors
Turkish Neurosurgical Society · 2022 SCI-Expanded
Prof. Dr. YAVUZ KÖKSAL →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Solitary metastasis of renal cell carcinoma to the third ventricle mimicking a colloid cyst case report
2015 ISSN: 1019-5149 SCI-Expanded
Prof. Dr. ENDER KÖKTEKİR →
Intracranial Giant Tuberculoma Mimicking Brain Tumor A Case Report
2015 ISSN: 1019-5149 SCI-Expanded
Prof. Dr. ŞUA SÜMER →
Intracranial Giant Tuberculoma Mimicking Brain Tumor A Case Report
2015 ISSN: 1019-5149 SCI-Expanded
Prof. Dr. NAZLIM AKTUĞ DEMİR →
The effect of bevacizumab on spinal epidural fibrosis in a postlaminectomy rat model
2012 ISSN: 1019-5149 SCI-Expanded 4 atıf
Prof. Dr. ENDER KÖKTEKİR →
Characterization of an intracranial neurothekeoma Case report
2010 ISSN: 1019-5149 SCI-Expanded
Prof. Dr. ENDER KÖKTEKİR →
Intracranial giant tuberculoma mimicking brain tumor a case report
2015 ISSN: 1019-5149 SCI-Expanded
Prof. Dr. ENDER KÖKTEKİR →
Endoscopic endonasal transsphenoidal treatment for acromegaly 2010 consensus criteria for remission and predictors of outcomes
2014 ISSN: 1019-5149 SCI-Expanded
Doç. Dr. MERT ŞAHİNOĞLU →
Preliminary experience with squid a new liquid embolizing agent for avm av fistulas and tumors
2014 ISSN: 1019-5149 SCI-Expanded
Doç. Dr. MERT ŞAHİNOĞLU →
Incidence hormonal distribution and postoperative follow up of atypical pituitary adenomas
2013 ISSN: 1019-5149 SCI-Expanded
Doç. Dr. MERT ŞAHİNOĞLU →
Traumatic Acute Subdural Hematomas: Analysis of Outcomes and Predictive Factors at a Single Center
2017 ISSN: 1019-5149 SCI-Expanded
Doç. Dr. MERT ŞAHİNOĞLU →
Vagal nerve stimulation has robust effects on neuropsychiatric assessment in resistant epilepsy: a clinical series with clinical experiences.
2018 ISSN: 1019-5149 SCI-Expanded
Doç. Dr. AHMET HAKAN EKMEKCİ →
The relationship between vasoactive-inotropic score and mortality in the adult patients with traumatic brain injury managed in the intensive care unit
2019 ISSN: 1019-5149 SCI-Expanded
Doç. Dr. MERT ŞAHİNOĞLU →
Comparison of glasgow coma scale and full outline of unresponsiveness (four) score: a prospective study
2019 ISSN: 1019-5149 SCI-Expanded Q4
Doç. Dr. MERT ŞAHİNOĞLU →
Comparison of glasgow coma scale and full outline of unresponsiveness (four) score: a prospective study
2019 ISSN: 1019-5149 SCI-Expanded
Dr. Öğr. Üyesi YEŞİM ŞERİFE BAYRAKTAR →
The relationship between vasoactive-inotropic score and mortality in the adult patients with traumatic brain injury managed in the intensive care unit
2019 ISSN: 1019-5149 SCI-Expanded
Dr. Öğr. Üyesi YEŞİM ŞERİFE BAYRAKTAR →
The relationship between vasoactive-inotropic score and mortality in the adult patients with traumatic brain injury managed in the intensive care unit
2018 ISSN: 1019-5149 SCI-Expanded
Prof. Dr. MEHMET SARGIN →
Comparison of Glasgow Coma Scale and Full Outline ofUnresponsiveness (Four) Score: A Prospective Study
2019 ISSN: 1019-5149 SCI-Expanded Q4
Prof. Dr. FARUK ÇİÇEKCİ →
Comparison of glasgow coma scale and full outline of unresponsiveness (four) score: a prospective study
2019 ISSN: 1019-5149 SCI-Expanded
Prof. Dr. İNCİ KARA →
The relationship between vasoactive-inotropic score and mortality in the adult patients with traumatic brain injury managed in the intensive care unit
2019 ISSN: 1019-5149 SCI-Expanded
Prof. Dr. JALE BENGİ ÇELİK →
Makale Bilgileri
Dergi
Turkish Neurosurgery
ISSN10195149
Yayın TarihiOcak 2022
Cilt / Sayfa32 · 135-142
Scopus ID2-s2.0-85123246592
Erişim🔓 Açık Erişim
Özet
AIM: To evaluate the clinical features, treatment approaches, and outcomes of glial tumors in children. MATERIAL and METHODS: Files (2006 to 2020) of children diagnosed with glial tumors and followed-up were reviewed retrospectively. Information regarding demographic and clinical characteristics, treatment approaches, and outcomes were retrieved from the patients’ files. RESULTS: Of the total of 180 pediatric patients diagnosed with brain tumors, 73 (40.6%) had glial tumors. The children with astrocytoma were in the age range of 2–18 years (median age: 8.7 years), while the ages of children with ependymoma ranged from three months to 10 years (median age: 3 years). This difference was statistically significant (p<0.0001). The male to female ratio was 1.6. The most common symptoms or signs were headaches (n=34, 46.6%), abnormal gait or coordination (n=22, 30.2%), vomiting (n=21, 28.8%), and cranial nerve palsies (n=20, 27.4%). The pathological diagnoses were astrocytomas (n=53, 72.6%), oligodendroglial tumors (n=2, 2.7%), ependymoma (n=15, 20.7%), and other glial tumors (n=3, 4.1%). The most common tumor location was supratentorial (n=42, 57.5%), while midline glioma was detected in seven patients. The 5-year overall survival (OS) rate of all glial tumors, astrocytoma, and ependymoma was 42%, 40%, and 55%, respectively. The 5-year OS rate of the tumor Grade I, II, III, and IV was 77.2%, 45%, 32%, and 0%, respectively (p<0.0001). The 5-year OS rate of supratentorial, infratentorial, and spinal tumors was 25.6%, 63.6%, and 50%, respectively (p=0.021). In Cox regression analysis, it was found that the tumor resection and grade had an effect on the tumor prognosis. CONCLUSION: Treatment results are not satisfactory in high-grade astrocytomas. There is a need for new treatment approaches that would take cognizance of molecular features and adopt multidisciplinary approaches.
Yazarlar (7)
1
Buket Kara
2
Kubra Ertan
3
Pınar Karabağlı
ORCID: 0000-0002-5558-0175
4
Hakan Karabagli
5
Güler Yavaş
6
Ahmet Okay Caglayan
ORCID: 0000-0002-2332-322X
7
Yavuz Koksal
Anahtar Kelimeler
Children
Glial tumors
Outcome
Treatment approaches
Kurumlar
Dokuz Eylül Üniversitesi
Izmir Turkey
Selçuk Tip Fakültesi
Konya Turkey
Yale School of Medicine
New Haven United States
Scimago Dergi (ISSN Eşleşmesi)
Turkish Neurosurgery
Q3
SJR Skoru0,330
H-Index39
YayıncıTurkish Neurosurgical Society
ÜlkeTurkey
Neurology (clinical) (Q3)
Surgery (Q3)
Metrikler
2
Atıf
7
Yazar
4
Anahtar Kelime