Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Interleukin-1β and tumour necrosis factor-α levels in periapical exudates
International Endodontic Journal · Şubat 2002
YÖKSİS Kayıtları
Interleukin 1 beta and tumour necrosis factor alpha levels in periapical exudates
INTERNATIONAL ENDODONTIC JOURNAL · 2002 SCI-Expanded 40 atıf
PROFESÖR SEYFULLAH HALİLOĞLU →
Makale Bilgileri
DergiInternational Endodontic Journal
Yayın TarihiŞubat 2002
Cilt / Sayfa35 · 181-185
Scopus ID2-s2.0-0036484953
Erişim🔓 Açık Erişim
Özet
Aim The aim of this study was to determine IL-1β and TNF-α levels in periapical exudates and to evaluate their relationship with clinical and radiological findings. Methodology Periapical exudates were collected from root canals of 35 single-rooted teeth using absorbent paper points. IL-1β and TNF-α levels were determined by enzyme-linked immunosorbent assays. The samples were divided into two groups according to the presence or absence of clinical signs including swelling and/or fistula, pain on palpation and/or percussion, and pus discharge from canals. Periapical exudate samples were divided into two groups according to size of periapical radiolucent area. Results The mean concentration of IL-1β (72.79 ng mL-1) in periapical exudates was approximately 12-fold higher than TNF-α (6.17 ng mL-1). There was no significant correlation between these cytokines (P > 0.05). IL-1β levels in canals with larger radiolucent areas (long axis ≥1 cm) were significantly higher than those with small areas (P < 0.05). There was a tendency toward higher levels of IL-1β in groups with clinical signs, but the differences were not significant (P > 0.05). Conclusions Periapical exudate levels of both cytokines failed to reflect periapical disease state.
Yazarlar (6)
1
Tamer Ataoglu
2
Mete Ungor
3
B. Serpek
4
S. Haliloglu
5
Hanife Ataoglu
6
Hale Ari
Anahtar Kelimeler
Interleukin-1β
Periapical diseases
Periapical granuloma
Tumour necrosis factor-α
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
71
Atıf
6
Yazar
4
Anahtar Kelime