Scopus
YÖKSİS DOI Eşleşti
SJR Q1
Effects of smoking on clinical parameters and the gingival crevicular fluid levels of IL-6 and TNF-α in patients with chronic periodontitis
Journal of Clinical Periodontology · Şubat 2004
YÖKSİS Kayıtları
Effects of smoking on clinical parameters and the gingival crevicular fluid levels of IL 6 and TNF alpha in patients with chronic periodontitis
JOURNAL OF CLINICAL PERIODONTOLOGY · 2004 SCI-Expanded 35 atıf
Prof. Dr. SEYFULLAH HALİLOĞLU →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Investigation of matrix metalloproteinase 1 1607 1G 2G polymorphism in a Turkish population with periodontitis
2008 ISSN: 03036979 SCI-Expanded 12 atıf
Prof. Dr. SEMA HAKKI →
Effects of smoking on clinical parameters and the gingival crevicular fluid levels of IL 6 and TNF alpha in patients with chronic periodontitis
2004 ISSN: 0303-6979 SCI-Expanded 35 atıf
Prof. Dr. SEYFULLAH HALİLOĞLU →
Investigation of matrix metalloproteinase 1 1607 1G 2G polymorphism in a Turkish population with periodontitis
2008 ISSN: 03036979 SCI-Expanded
Prof. Dr. ERDOĞAN EŞREF HAKKI →
Isolation of palatal adipose tissue mesenchymalstem cells PAT MSCs
2015 ISSN: 03036979 SCI-Expanded
Prof. Dr. ERDOĞAN EŞREF HAKKI →
Makale Bilgileri
ISSN03036979
Yayın TarihiŞubat 2004
Cilt / Sayfa31 · 99-104
Scopus ID2-s2.0-1642633684
Özet
Objective: Smoking is an important environmental risk factor for the initiation and progression of periodontal diseases. The aim of this study was to evaluate the effects of smoking on clinical parameters and the gingival crevicular fluid (GCF) contents of the pro-inflammatory cytokines interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) levels in patients with chronic periodontitis. Material and Methods: The study base consisted of 41 patients including 22 volunteer current smokers with an age range of 32-59 (44.41 ± 7.88) years and 19 volunteer non-smokers with an age range of 36-59 (46.94 ± 6.07) years. The first month after non-surgical periodontal therapy was accepted as the baseline of the study. The clinical parameters including plaque index (PI), gingival index (GI), bleeding on probing (BOP), probing depth (PD), clinical attachment loss (CAL) were recorded and GCF samples were collected for analysis of GCF contents of DL-6 and TNF-α levels. At the 3rd and 6th months, all of these procedures were repeated. Results: In smokers, only CAL was significantly higher at the 3rd month compared with non-smokers (p < 0.05). GI and BOP were higher in non-smokers than smokers in both periods (p < 0.05). PI showed increases from the initial to the 6th month in smokers (p < 0.05). Although the differences between two groups with regard to EL-6 and TNF-α were not significant (p > 0.05), the total amount of TNF-α in GCF decreased from the initial to the 6th month in smokers (p < 0.05). There were no significant correlations between the mean total amount of IL-6 and TNF-α in GCF and clinical parameters in both evaluation periods in smokers (p > 0.05). Conclusion: The present study demonstrated that cigarette smoking increases the amount of dental plaque over time in smokers and does not influence GCF contents of IL-6 and TNF-α. © Blackwell Munksgaard, 2004.
Yazarlar (3)
1
Ebru Olgun Erdemir
2
I. Duran
3
S. Haliloglu
Anahtar Kelimeler
Chronic periodontitis
GCF
IL-6
Non-surgical therapy
Smoking
TNF-α
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Journal of Clinical Periodontology
Q1
SJR Skoru2,543
H-Index187
YayıncıBlackwell Munksgaard
ÜlkeDenmark
Periodontics (Q1)
Metrikler
76
Atıf
3
Yazar
6
Anahtar Kelime