Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Interleukin-1 receptor antagonist levels in gingival crevicular fluid and serum in nonsmoking women with preterm low birth weight and intrauterine growth retardation
European Journal of Dentistry · Ocak 2015
YÖKSİS Kayıtları
Interleukin 1 receptor antagonist levels in gingivalcrevicular fluid and serum in nonsmoking womenwith preterm low birth weight and intrauterinegrowth retardation
European Journal of Dentistry · 2015 PUBMED
PROFESÖR SEYFULLAH HALİLOĞLU →
Makale Bilgileri
DergiEuropean Journal of Dentistry
Yayın TarihiOcak 2015
Cilt / Sayfa9 · 109-116
Scopus ID2-s2.0-84921753010
Erişim🔓 Açık Erişim
Özet
Objective: The aim of this study was to evaluate interleukin (IL)-1 β and IL-1 receptor antagonist (IL-1ra) levels in gingival crevicular fluid (GCF) and serum (S) in nonsmoking women with normal birth (NB), preterm low birth weight (PLBW), and intra-uterine growth retardation (IUGR). Materials and Methods: In this unmatched case-control study design, 64 women with NB, 45 women with PLBW, and 47 women with IUGR were recruited within 24 h delivery. Clinical periodontal parameters were recorded. IL-1 β and IL-1ra levels in GCF (pg/30 s) and serum (pg/ml) of were evaluated using commercial enzyme immunoassay and ELISA kits. Results: Greater pocket depth and clinical attachment loss were observed in PLBW and IUGR women than in NB women (P < 0.05). The total amounts of IL-1ra and IL-β of GCF were higher levels in NB women than PLBW and IUGR women (P < 0.05). The lowest total amount of IL-1ra of GCF was found in IUGR women (P < 0.05). The concentrations of IL-1ra in serum samples were not statistically significant for any of the study groups (P > 0.05). Conclusion: It can be suggested that worse periodontal conditions and the low levels of IL-1ra in GCF may be an important factor in adverse pregnancy outcomes.
Yazarlar (3)
1
Nezahat Arzu Kayar
ORCID: 0000-0002-2325-2900
2
Nilgun Ozlem Alptekin
3
S. Haliloglu
Anahtar Kelimeler
Cytokine(s)
Gingival crevicular fluid
Periodontal-systemic disease interactions
Serum
Kurumlar
Başkent Üniversitesi
Ankara Turkey
Republic of Turkey Ministry of Food
Antakya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
6
Atıf
3
Yazar
4
Anahtar Kelime