Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Effect of high fructose consumption on plasma levels of leptin, adropin and insulin, and serum biochemical parameters in mature adult rats
Tropical Journal of Pharmaceutical Research · Kasım 2022
YÖKSİS Kayıtları
Effect of high fructose consumption on plasma levels of leptin, adropin and insulin, and serum biochemical parameters in mature adult rats
Tropical Journal of Pharmaceutical Research · 2022 SCI-Expanded
PROFESÖR SEYFULLAH HALİLOĞLU →
Makale Bilgileri
DergiTropical Journal of Pharmaceutical Research
Yayın TarihiKasım 2022
Cilt / Sayfa21 · 2397-2402
Scopus ID2-s2.0-85143624578
Erişim🔓 Açık Erişim
Özet
Purpose: To determine the effect of high-fructose consumption on plasma levels of insulin, leptin, and adropin, as well as serum biochemical parameters in mature adult rats. Methods: Sixteen (16) mature adult rats were assigned to control group (CG) and fructose group (FG). The CG was fed ad libitum with standard rat feed and drinking water, while FG was fed standard rat feed and 20 % fructose in drinking water for 8 weeks. Plasma hormonal analyses for insulin, leptin and adropin were performed by enzyme-linked immunosorbent assay (ELISA), while serum biochemical analysis was carried out with an autoanalyzer. Results: In FG, plasma levels of insulin and leptin significantly increased, while adropin levels decreased, when compared to CG (p < 0.05). On the other hand, while serum glucose and triglycerides were significantly increased by fructose feeding, total cholesterol, HDL-C and ALT levels were decreased (p < 0.05). Conclusion: High fructose consumption triggers metabolic syndrome in mature adult similar to young rats, resulting in hyperleptinemia and hyperinsulinemia. Moreover, high fructose consumption decreases plasma adropin levels.
Yazarlar (2)
1
Hale Ergin Eğritağ
2
S. Haliloglu
Anahtar Kelimeler
Adropin
Fructose
Insulin
Leptin
Kurumlar
Burdur Mehmet Akif Ersoy Üniversitesi
Burdur Turkey
Selçuk Üniversitesi
Selçuklu Turkey