Scopus
YÖKSİS Eşleşti
A Multicentered Study on Epidemiologic and Clinical Characteristics of 37 Neonates With Community-acquired COVID-19
Pediatric Infectious Disease Journal · Ekim 2020
YÖKSİS Kayıtları
A Multicentered Study on Epidemiologic and Clinical Characteristics of 37 Neonates With Community-acquired COVID-19
PEDIATRIC INFECTIOUS DISEASE JOURNAL · 2020 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ SAİME SÜNDÜS UYGUN →
Makale Bilgileri
DergiPediatric Infectious Disease Journal
Yayın TarihiEkim 2020
Cilt / Sayfa39 · E297-E302
Scopus ID2-s2.0-85091053659
Özet
Background: Coronavirus disease 2019 (COVID-19) primarily affects adults and spares children, whereas very little is known about neonates. We tried to define the clinical characteristics, risk factors, laboratory, and imagining results of neonates with community-acquired COVID-19. Methods: This prospective multicentered cohort study included 24 neonatal intensive care units around Turkey, wherein outpatient neonates with COVID-19 were registered in an online national database. Full-term and premature neonates diagnosed with COVID-19 were included in the study, whether hospitalized or followed up as ambulatory patients. Neonates without severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) via reverse transcriptase-polymerase chain reaction testing or whose mothers had been diagnosed with COVID-19 during pregnancy were excluded. Results: Thirty-seven symptomatic neonates were included. The most frequent findings were fever, hypoxemia, and cough (49%, 41%, 27%, respectively). Oxygen administration (41%) and noninvasive ventilation (16%) were frequently required; however, mechanical ventilation (3%) was rarely needed. Median hospitalization was 11 days (1-35 days). One patient with Down syndrome and congenital cardiovascular disorders died in the study period. C-reactive protein (CRP) and prothrombin time (PT) levels were found to be higher in patients who needed supplemental oxygen (0.9 [0.1-8.6] vs. 5.8 [0.3-69.2] p = 0.002, 11.9 [10.1-17.2] vs. 15.2 [11.7-18.0] p = 0.01, respectively) or who were severe/critical (1.0 [0.01-8.6] vs. 4.5 [0.1-69.2] p = 0.01, 11.7 [10.1-13.9] vs. 15.0 [11.7-18.0] p = 0.001, respectively). Conclusions: Symptomatic neonates with COVID-19 had high rates of respiratory support requirements. High CRP levels or a greater PT should alert the physician to more severe disease.
Yazarlar (28)
1
Mehmet Kenan Kanburoglu
2
Cuneyt Tayman
3
Mehmet Yekta Oncel
4
Ilke Mungan Akin
ORCID: 0000-0002-3677-1582
5
Emrah Can
6
Nihat Demir
7
Sema Arayici
8
Demet Orhan Baser
9
Ibrahim Caner
10
Asli Memisoglu
11
Saime Sundus Uygun
12
Selahattin Akar
13
Mustafa Ali Akin
14
Emel Ataoglu
15
Handan Bezirganoglu
16
Leyla Bilgin
17
Senol Bozdag
18
Serdar Cömert
19
Resat Gurpinar
20
Ebru Yalin Imamoglu
21
Timucin Imdadoglu
22
Fatma Narter
23
Ramazan Ozdemir
24
Handan Hakyemez Toptan
25
Emine Esin Yalinbas
26
Akan Yaman
27
Ömer Erdeve
28
Esin Koc
Anahtar Kelimeler
acute respiratory distress syndrome
coronavirus infections
COVID-19
newborn
SARS-CoV-2
Kurumlar
Adiyaman Üniversitesi
Adiyaman Turkey
Ankara Üniversitesi
Ankara Turkey
Batman Obstetric ve Pediatric Hospital
Batman Turkey
Gazi University, Faculty of Medicine
Ankara Turkey
Haseki Education and Research Hospital
Istanbul Turkey
Health Ministry Eskisehir City Hospital
Eskisehir Turkey
Inönü Üniversitesi Tip Fakültesi
Malatya Turkey
Istanbul Üniversitesi
Istanbul Turkey
İzmir Kâtip Çelebi Üniversitesi
Izmir Turkey
Kahramanmaras Necip Fazil City Hospital
Kahramanmaras Turkey
Kartal Dr. Lütfi Kırdar City Hospital
Istanbul Türkiye
Kocaeli Üniversitesi
İzmit Turkey
Kütahya Sağlık Bilimleri Üniversitesi
Kutahya Turkey
Marmara Üniversitesi Tip Fakültesi
Istanbul Turkey
Nişantaşı Üniversitesi
Istanbul Turkey
Okan Üniversitesi
Tuzla Turkey
Ondokuz Mayis Üniversitesi
Samsun Turkey
Ozel Esencan Hospital
Istanbul Turkey
Recep Tayyip Erdogan University
Rize Turkey
Sakarya Üniversitesi
Serdivan Turkey
T.C. Saglik Bakanligi Istanbul Goztepe Egitim ve Arastirma Hastanesi
Goztepe Turkey
T.C. Sağlık Bakanlığı,
Ankara Turkey
University of Health Sciences
Istanbul Turkey
Metrikler
34
Atıf
28
Yazar
5
Anahtar Kelime