Scopus
YÖKSİS DOI Eşleşti
SJR Q3
Relationship between left ventricular mass and carotid intima media thickness in obese adolescents with non-alcoholic fatty liver disease
Journal of Pediatric Endocrinology and Metabolism · Ekim 2012
YÖKSİS Kayıtları
Relationship between left ventricular mass and carotid intima media thickness in obese adolescents with non-alcoholic fatty liver disease
Journal of Pediatric Endocrinology and Metabolism · 2012 SCI-Expanded
Prof. Dr. AHMET SERT →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Oxidative stress in childhood obesity
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Smith Lemli Opitz syndrome Autopsy with new morphological findings
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The relation of vitamin D deficiency with puberty and insulin resistance in obese children and adolescents.
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Assessment of thyroid gland vascularity with superb microvascular imaging in healthy children and its relationship with potential factors
2020 ISSN: 0334-018X SCI
Prof. Dr. MEHMET SEDAT DURMAZ →
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2007 ISSN: 0334-018X SCI-Expanded Q3
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Doç. Dr. MUAMMER BÜYÜKİNAN →
The clinical presentation and genetic diagnosis of Tangier disease in the pediatric age group
2025 ISSN: 0334-018X SCI-Expanded Q4
Dr. Öğr. Üyesi BANU KADIOĞLU YILMAZ →
Makale Bilgileri
ISSN0334018X
Yayın TarihiEkim 2012
Cilt / Sayfa25 · 927-934
Scopus ID2-s2.0-84867830463
Özet
Background/aims: No data are available examining the relationship between carotid intima media thickness (IMT) and left ventricular mass (LVM) in obese adolescents with non-alcoholic fatty liver disease (NAFLD). Therefore, we investigated LVM and carotid IMT in obese adolescents with NAFLD. Methods: Eighty obese adolescents and 37 lean subjects were enrolled in the study. The obese subjects were divided into two subgroups based on the presence or absence of fatty liver with high transaminases (NAFLD group and non-NAFLD group). Fasting blood samples were assayed for serum transaminases, glucose and insulin levels. Insulin resistance was calculated by the homeostasis model assessment (HOMA-IR). Results: LVM measurements were higher in both NAFLD and non-NAFLD obese patients in comparison with the lean children. The NAFLD group had significantly higher LVM measurements than the non-NAFLD and lean groups. Carotid IMT was higher in both the NAFLD and non-NAFLD obese patients in comparison with the lean group. The NAFLD group had significantly higher carotid IMT measurements than the non-NAFLD and lean groups. LVM was positively correlated with HOMA-IR and serum alanine aminotransferase levels in the NAFLD obese group. Carotid IMT was positively correlated with HOMAIR, serum alanine aminotransferase levels and LVM in the NAFLD obese group. Conclusions: We demonstrated that obese adolescents with NAFLD have increased LVM and carotid IMT and low insulin sensitivity. Obese adolescents with NAFLD and increased carotid IMT may demonstrate a more adverse cardiovascular risk profile and higher LVM. Therefore, assessment of carotid IMT, in addition to echocardiography, may assist in risk stratification in obese adolescents with NAFLD with elevated cardiovascular risk factor levels.
Yazarlar (5)
1
Ahmet Sert
ORCID: 0000-0002-1607-7569
2
Ozgur Pirgon
3
Ebru Aypar
4
Hakan Yilmaz
5
Dursun Odabas
Anahtar Kelimeler
Adolescent
Carotid intima media thickness
Insulin resistance
Left ventricular mass
Non-alcoholic fatty liver disease
Kurumlar
Konya Meram Training and Research Hospital
Konya Turkey
Süleyman Demirel Üniversitesi
Isparta Turkey
Scimago Dergi (ISSN Eşleşmesi)
Journal of Pediatric Endocrinology and Metabolism
Q3
SJR Skoru0,363
H-Index76
YayıncıWalter de Gruyter GmbH
ÜlkeGermany
Endocrinology, Diabetes and Metabolism (Q3)
Pediatrics, Perinatology and Child Health (Q3)
Endocrinology (Q4)
Metrikler
27
Atıf
5
Yazar
5
Anahtar Kelime