Scopus
YÖKSİS Eşleşti
Lactate and lactate dehydrogenase in predicting the severity of transient tachypnea of the newborn
Journal of Maternal-Fetal and Neonatal Medicine · Ağustos 2013
YÖKSİS Kayıtları
Lactate and lactate dehydrogenase in predicting the severity of transient tachypnea of the newborn
The Journal of Maternal-Fetal Neonatal Medicine · 2013 SCI-Expanded
PROFESÖR AHMET SERT →
Makale Bilgileri
DergiJournal of Maternal-Fetal and Neonatal Medicine
Yayın TarihiAğustos 2013
Cilt / Sayfa26 · 1245-1248
Scopus ID2-s2.0-84880302300
Özet
Objective: Low Apgar score is strongly associated with the incidence of transient tachypnea of the newborn (TTN) and other respiratory diseases of the newborn. We aimed to investigate the relationship between hypoxia determinants and the prolonged oxygen and respiratory support requirement even if the Apgar scores were normal. Methods: Retrospective case-controlled study. Infants born after 35 weeks of gestational age with clinical signs, chest X-ray findings and clinical course consistent with TTN were included. Receiver operating characteristic curves were used to assess the predictive values of determinants in predicting the risk for prolonged oxygen requirement and mechanical ventilatory support. Results: We showed a positive correlation between the duration of oxygen with lactate and lactate dehydrogenase (LDH) levels. LDH offered the best predictive value for prolonged oxygen requirement with a positive predictive value (PPV) of 88.9%. The predictive value of lactate exceeds the predictive value of LDH, aspartate aminotransferase, and percentage of normoblasts to predict the requirement of respiratory support with a PPV of 88.5%. Conclusions: Lactate and LDH might be useful for clinicians at first level hospitals for decision making to refer the TTN patient to the secondary or tertiary level neonatal intensive care unit before the clinical situation is worsened. © 2013 Informa UK Ltd. All rights reserved: reproduction in whole or part not permitted.
Yazarlar (6)
1
Servet Ozkiraz
2
Zeynel Gökmen
3
Saltuk Bugra Boke
4
Hasan Kilicdag
5
Deniz Ozel
6
Ahmet Sert
ORCID: 0000-0002-1607-7569
Anahtar Kelimeler
Lactate
Lactate dehydrogenase
Transient tachypnea of the newborn
Kurumlar
Acıbadem Hospital
Adana Turkey
Akdeniz Üniversitesi
Antalya Turkey
Başkent Üniversitesi
Ankara Turkey
Konya Education and Research Hospital
Konya Turkey
Metrikler
18
Atıf
6
Yazar
3
Anahtar Kelime