Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Prevalence of rotavirus genotypes in children younger than 5 years of age before the introduction of a universal rotavirus vaccination program: Report of Rotavirus Surveillance in Turkey
PLoS ONE · Aralık 2014
YÖKSİS Kayıtları
Prevalence of Rotavirus Genotypes in Children Younger than 5 Years of Age before the Introduction of a Universal Rotavirus Vaccination Program: Report of Rotavirus Surveillance in Turkey
PLoS One · 2014 SCI-Expanded
DOÇENT MELİKE EMİROĞLU →
Makale Bilgileri
DergiPLoS ONE
Yayın TarihiAralık 2014
Cilt / Sayfa9
Scopus ID2-s2.0-84914690138
Erişim🔓 Açık Erişim
Özet
Background: Group A rotaviruses are the most common causative agent of acute gastroenteritis among children less than 5 years of age throughout the world. This sentinel surveillance study was aimed to obtain baseline data on the rotavirus G and P genotypes across Turkey before the introduction of a universal rotavirus vaccination program. Methods: Rotavirus antigen-positive samples were collected from 2102 children less than 5 years of age who attended hospitals participating in the Turkish Rotavirus Surveillance Network. Rotavirus antigen was detected in the laboratories of participating hospitals by commercial serological tests such as latex agglutination, immunochromatographic test or enzyme immunoassay. Rotavirus G and P genotypes were determined by reverse transcription polymerase chain reaction (RT-PCR) using consensus primers detecting the VP7 and VP4 genes, followed by semi-nested type-specific multiplex PCR. Results: RT-PCR found rotavirus RNA in 1644 (78.2%) of the samples tested. The highest rate of rotavirus positivity (38.7%) was observed among children in the 13 to 24 month age group, followed by children in the age group of 25 to 36 months (28.3%). A total of eight different G types, six different P types, and 42 different G-P combinations were obtained. Four common G types (G1, G2, G3, and G9) and two common P types (P[8] and P[4]) accounted for 95.1% and 98.8% of the strains, respectively. G9P[8] was the most common G/P combination found in 40.5% of the strains followed by G1P[8] (21.6%), G2P[8] (9.3%), G2P[4] (6.5%), G3P[8] (3.5%), and finally, G4P[8] (3.4%). These six common genotypes included 83.7% of the strains tested in this study. The rate of uncommon genotypes was 14%. Conclusion: The majority of the strains analyzed belonged to the G1-G4 and G9 genotypes, suggesting high coverage of current rotavirus vaccines. This study also demonstrates a dramatic increase in G9 genotype across the country.
Yazarlar (83)
1
Riza Durmaz
2
Atila Taner Kalaycioglu
3
Sumeyra Acar
4
Zekiye Bakkaloglu
5
Alper Karagoz
6
Gulay Korukluoglu
7
Mustafa Ertek
8
M. A. Torunoglu
9
Selma Gokahmetoglu
10
Adnan Öztürk
11
Aysen Bayram
12
Nilgun Col Araz
13
Fatma Bacalan
14
Ozlem Ozgur Gundeslioglu
15
Ekrem Yaşar
16
Mustafa Altindis
17
Aysegul Bukulmez
18
Betugul Ongen
19
Ayper Somer
20
Banu Bayraktar
21
Nazan Dalgic Karabulut
22
Hakan Uslu
23
Ferda Aktas
24
Ömer Kılıç
25
Aysegul Copur Cicek
26
Selim Dereci
27
Sebahat Aksaray
28
Cagatay Nuhoglu
29
Riza Adaleti
30
Gulendam Bozdayi
31
H. Tezer
32
Derya Mutlu
33
Aygen Yilmaz
34
Ali Osman Sekercioglu
35
Gul Durmaz
ORCID: 0000-0002-2002-8380
36
Mustafa Hacımustafaoğlu
37
Cüneyt Özakin
38
Solmaz Çelebi
39
Seda Tezcan
40
Gonul Aslan
41
Esin Ark
42
Ebru Sozen
43
Gonul Tanir
44
Sengul Ozkan
45
Hulya Zararsiz
46
Umit Celik
47
Emel Sesli Cetin
48
Metehan Oz
49
Ilker Devrim
50
Suleyman Bayram
51
Yelda Sorguc
52
Erdal Ince
53
Haluk Güriz
54
Bilge Aldemir Kocabas
55
Hüseyin Güdücüoğlu
56
Oguz Tuncer
57
Faruk Aydın
58
E. Erduran
59
Zafer Cetinkaya
60
Haluk Vahaboglu
61
Figen Temel Kelesyan
62
Murat Anil
63
Dilek Yilmaz
64
Candan Cicek
65
Eylem Ulas Saz
66
Zumrut Sahbudak
67
Semra Sen
68
Zafer Kurugöl
69
Cafer Eroglu
70
Ahmet Guzel
71
Bahadir Feyzioglu
72
Melike Emiroglu
ORCID: 0000-0003-1307-0246
73
Fadile Yildiz Zeyrek
74
Alpay Cakmak
75
Emine Kocabas
76
Ayse Selimoglu
77
Çiğdem Kuzucu
78
Ahmet Soysal
79
Mustafa Bakır
80
Ayşegül Yağcı
81
Yavuz Uyar
82
Ahmet Ozlu
83
Fehminaz Temel
Kurumlar
Afyon Kocatepe Üniversitesi Tıp Fakültesi
Afyonkarahisar Turkey
Akdeniz Üniversitesi
Antalya Turkey
Ankara Üniversitesi
Ankara Turkey
Ankara Yildirim Beyazit University
Ankara Turkey
Antalya Education and Research Hospital
Antalya Turkey
Ataturk University, Faculty of Medicine
Erzurum Turkey
Bursa Uludağ Üniversitesi
Bursa Turkey
Children's Hospital
Diyarbakir Turkey
Cotton Research and Application Center
Adana Turkey
Çukurova Üniversitesi Tip Fakültesi
Adana Turkey
Dr. Behçet Uz Children Research and Training Hospital
Izmir Turkey
Dr. Sami Ulus Maternity and Children's Hospital
Ankara Turkey
Erciyes University, Faculty of Medicine
Kayseri Turkey
Erzurum Regional Training and Research Hospital
Erzurum Türkiye
Eskişehir Osmangazi Üniversitesi Tip Fakültesi
Eskisehir Turkey
Gaziantep Üniversitesi
Gaziantep Turkey
Gazi University, Faculty of Medicine
Ankara Turkey
Göztepe Teaching and Research Hospital
Istanbul Turkey
Harran Üniversitesi
Sanliurfa Turkey
Inönü Üniversitesi Tip Fakültesi
Malatya Turkey
İstanbul Tıp Fakültesi
Istanbul Turkey
Karadeniz Technical University
Trabzon Turkey
Marmara Üniversitesi
Istanbul Turkey
Maternity and Children Hospital
Mersin Turkey
Maternity Hospital
Adana Turkey
Meram Medical Faculty
Konya Turkey
Mersin Üniversitesi Tip Fakültesi
Mersin Turkey
Ondokuz Mayis Üniversitesi
Samsun Turkey
Public Health Institution of Turkey
Ankara Turkey
Recep Tayyip Erdogan University
Rize Turkey
Sisli Etfal Research and Educational Hospital
Istanbul Turkey
Süleyman Demirel Üniversitesi
Isparta Turkey
Sultan 2.Abdülhamid Han Eğitim ve Araştirma Hastanesi
Uskudar Turkey
T.C. Sağlık Bakanlığı,
Ankara Turkey
Tepecik Training and Research Hospital
Izmir Turkey
University Medical Faculty
Izmir Turkey
Van Yüzüncü Yıl Üniversitesi
Van Turkey
Metrikler
44
Atıf
83
Yazar