Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
High-risk febrile neutropenia and its management in children with solid tumors and lymphoma
Turkish Journal of Medical Sciences · Ocak 2015
YÖKSİS Kayıtları
High risk febrile neutropenia and its management in childrenwith solid tumors and lymphoma
TURKISH JOURNAL OF MEDICAL SCIENCES · 2015 SCI-Expanded
PROFESÖR YAVUZ KÖKSAL →
Makale Bilgileri
DergiTurkish Journal of Medical Sciences
Yayın TarihiOcak 2015
Cilt / Sayfa45 · 655-662
Scopus ID2-s2.0-84929773487
Erişim🔓 Açık Erişim
Özet
Background/aim: The clinical characteristics and treatment results of febrile neutropenia attacks that occurred in patients with lymphoma and solid tumors were analyzed. Materials and methods: A total of 50 patients with 94 high-risk attacks were evaluated for malignant diseases in this study. Results: The fever etiology was determined as clinical (50%), microbiological (5.31%), clinical-microbiological (5.31%), or unknown (39.3%). A few of the attacks (21.3%) were observed in lymphoma cases and 77.7% were observed in patients with solid tumors. Patients who were in remission had 59.6% of the attacks, and 39.4% occurred in patients not in remission. Among the groups tested, 73% (the imipenem/amikacin group) and 47.9% (the piperacillin-tazobactam/amikacin group) of patients were in remission. Glycopeptide addition rates in these groups were 22.2% and 40.8% and antifungal addition rates were 8.8% and 18.3%, respectively. Conclusion: Clinical progress was more problematic in patients who were not in remission during the attacks. Tis was due to the fact that some patients had other factors that placed them in the high-risk group, as well as increased C reactive protein and procalcitonin values on the frst day. Terefore, it may not be accurate to associate the success achieved in the diferent treatment regimens with antibiotics alone.
Yazarlar (3)
1
Dogan Kose
2
Melike Emiroglu
ORCID: 0000-0003-1307-0246
3
Yavuz Koksal
Anahtar Kelimeler
Childhood
Febrile
High risk
Neutropenia
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey