Scopus
🔓 Açık Erişim
High-level genetic diversity among invasive streptococcus pneumoniae isolates in Turkey
Japanese Journal of Infectious Diseases · Ocak 2016
Makale Bilgileri
DergiJapanese Journal of Infectious Diseases
Yayın TarihiOcak 2016
Cilt / Sayfa69 · 207-212
Scopus ID2-s2.0-84969135578
Erişim🔓 Açık Erişim
Özet
This study obtained information on the serotypes and molecular typing characteristics of Streptococcus pneumoniae strains causing invasive diseases in Turkey. Sixty-eight S. pneumoniae isolates causing invasive pneumococcal diseases were collected from different regions of Turkey from 2009 to 2011. The isolates were characterized by performing multilocus sequence typing (MLST), pulsed-field gel electrophoresis (PFGE), and capsular serotyping, and 25 different serotypes were identified. Serotypes 19F, 23F, 1, 14, and 7F were common and accounted for 52.9z of all the serotypes. In addition, 54 different PFGE profiles (pulsotypes) were observed. Twenty-three of the 68 (33.8z) isolates were clustered into 9 pulsotypes. MLST analysis yielded 36 sequence types, of which 12 (33.3z) were novel. A comparison of results with the global pneumococcal MLST database by performing eBURST analysis showed that our strains belonged to 20 different clonal complexes and 5 singletons. In addition, we identified 4 new alleles: 2 gdh, 1 xpt, and 1 ddl. Thus, the results of this study highlighted a high level of diversity among pneumococcal isolates. In addition, the study identified a case of possible capsular switching.
Yazarlar (64)
1
Dilek Guldemir
2
Sumeyra Acar
3
Selin Nar Otgun
4
Ozlem Unaldi
5
Aysegul Gozalan
6
Mustafa Ertek
7
Riza Durmaz
8
Özlem Açıkgöz
9
Ahmet Ayyıldız
10
Mustafa Bakır
11
Ahmet Celal Başustaoğlu
12
Mehmet Bayraktar
13
Betil Özhak Baysan
14
Solmaz Çelebi
15
Zeynep Çizmeci
16
Yildiz Dallar
17
Zeynep Ülker Enç
18
Hacer Ergin
19
Ülker Ertan
20
Duygu Findik
21
Suna Gedikoğlu
22
Meral Gültekin
23
Deniz Gür
24
Haluk Güriz
25
Mustafa Hacımustafağlu
26
Nevin Hatipoglu
27
Sadık Sami Hatipoğlu
28
Emine Hoşaf
29
Erdal Ince
30
Ilknur Kaleli
31
Mustafa Kara
32
Esra Karakoç
33
Şükrii Karakullukçu
34
Cemşit Karakurt
35
Melike Emiroglu
ORCID: 0000-0003-1307-0246
36
Abdullah Kiliç
37
Mesut Koçak
38
Çiğdem Kuzucu
39
Ali Müsevvitoğlu
40
Hülya Oskovi
41
Cüneyt Özakin
42
Nagihan Özlü
43
Sengul Ozkan
44
Mustafa Öztürk
45
Duygu Perçin
46
Kamuran Şanli
47
Ahmet Soysal
48
Burcin Sener
49
Zeynep Şengul
50
H. Tezer
51
Ülkü Tıraş
52
Muammer Töre
53
Inci Tuncer
54
Ozden Turel
55
Salih Türkoğlu
56
Heybet Tüzün
57
M. H. Uyanik
58
Dilara Uygun
59
Mustafa Varma
60
Ayşegül Yağcı
61
Ekrem Yaşar
62
Olcay Yeğin
63
Gülay Yetkin
64
Şükran Yildırım
Kurumlar
Ankara Yildirim Beyazit University
Ankara Turkey
Ataturk Training and Research Hospital
Izmir Turkey
Erzincan Binali Yıldırım Üniversitesi
Erzincan Turkey
National High Risk Pathogens Reference Laboratory
Ankara Turkey
National Molecular Microbiology Reference Laboratory
Ankara Turkey
Metrikler
5
Atıf
64
Yazar