Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Mycobacterial disease in patients with chronic granulomatous disease: A retrospective analysis of 71 cases
Journal of Allergy and Clinical Immunology · Temmuz 2016
YÖKSİS Kayıtları
Mycobacterial disease in patients with chronic granulomatous disease A retrospective analysis of 71 cases
Journal of Allergy and Clinical Immunology · 2016 SCI
DOÇENT MELİKE EMİROĞLU →
Makale Bilgileri
DergiJournal of Allergy and Clinical Immunology
Yayın TarihiTemmuz 2016
Cilt / Sayfa138 · 241-248.e3
Scopus ID2-s2.0-84959232445
Erişim🔓 Açık Erişim
Özet
Background Chronic granulomatous disease (CGD) is a rare primary immunodeficiency caused by inborn errors of the phagocyte nicotinamide adenine dinucleotide phosphate oxidase complex. From the first year of life onward, most affected patients display multiple, severe, and recurrent infections caused by bacteria and fungi. Mycobacterial infections have also been reported in some patients. Objective Our objective was to assess the effect of mycobacterial disease in patients with CGD. Methods We analyzed retrospectively the clinical features of mycobacterial disease in 71 patients with CGD. Tuberculosis and BCG disease were diagnosed on the basis of microbiological, pathological, and/or clinical criteria. Results Thirty-one (44%) patients had tuberculosis, and 53 (75%) presented with adverse effects of BCG vaccination; 13 (18%) had both tuberculosis and BCG infections. None of these patients displayed clinical disease caused by environmental mycobacteria, Mycobacterium leprae, or Mycobacterium ulcerans. Most patients (76%) also had other pyogenic and fungal infections, but 24% presented solely with mycobacterial disease. Most patients presented a single localized episode of mycobacterial disease (37%), but recurrence (18%), disseminated disease (27%), and even death (18%) were also observed. One common feature in these patients was an early age at presentation for BCG disease. Mycobacterial disease was the first clinical manifestation of CGD in 60% of these patients. Conclusion Mycobacterial disease is relatively common in patients with CGD living in countries in which tuberculosis is endemic, BCG vaccine is mandatory, or both. Adverse reactions to BCG and severe forms of tuberculosis should lead to a suspicion of CGD. BCG vaccine is contraindicated in patients with CGD.
Yazarlar (66)
1
Francesca Conti
2
Saul Oswaldo Lugo-Reyes
3
Lizbeth Blancas Galicia
4
Jianxin He
5
Guside Aksu
6
Edgar Borges de Oliveira
7
Caroline Deswarte
8
Marjorie Hubeau
9
Neslihan Karaca
10
Maylis de Suremain
11
Antoine Guérin
12
Laila Ait Baba
13
Carolina Prando
14
Gloria G. Guerrero
15
Melike Emiroglu
ORCID: 0000-0003-1307-0246
16
Fatma Nur Öz
ORCID: 0000-0001-8374-095X
17
Marco Antonio Yamazaki Nakashimada
18
Edith Gonzalez Serrano
19
Sara Espinosa
20
Isil Barlan
21
Nestor Pérez
22
Lorena Regairaz
23
Héctor Eduardo Guidos Morales
24
Liliana Bezrodnik
25
Daniela Di Giovanni
26
Ghassan Dbaibo
27
Fatima Ailal
28
Miguel Galicchio
29
Matias Oleastro
30
Jalel Chemli
31
Silvia Danielian
32
Laura Perez
33
Maria Claudia Ortega
34
Susana Soto Lavin
35
Joseph Hertecant
36
Ozden Anal
37
Nadia Kechout
38
Eman Al-Idrissi
39
Gehad Elghazali
40
Anastasiia Bondarenko
ORCID: 0000-0002-9737-2868
41
Liudmyla Chernyshova
42
Peter Ciznar
43
Rose Marie Herbigneaux
44
Aminata Diabate
45
Stéphanie Ndaga
46
Barik Konte
47
Ambre Czarna
48
Mélanie Migaud
49
Sigifredo Pedraza-Sánchez
50
Mussaret Bano Zaidi
51
Guillaume Vogt
52
Stéphane Blanche
53
Imen Benmustapha
54
Davood Mansouri
55
Laurent Abel
ORCID: 0000-0001-7016-6493
56
Stéphanie Boisson-Dupuis
57
Nizar Mahlaoui
58
Ahmed A. Bousfiha
59
Capucine Picard
60
Mohamed Rhida Barbouche
61
Saleh Zaid Al-Muhsen
62
Francisco J. Espinosa-Rosales
63
Necil Kütükçüler
64
Antonio Condino-Neto
ORCID: 0000-0002-1069-3117
65
Jean Laurent Casanova
ORCID: 0000-0002-7782-4169
66
Jacinta Bustamante
Anahtar Kelimeler
BCG
chronic granulomatous disease
Mycobacteria
primary immunodeficiency
tuberculosis
Kurumlar
American University of Beirut
Beirut Lebanon
Beijing Children's Hospital, Capital Medical University
Beijing China
CHU Réunion
Saint-Pierre de la Reunion France
CHU Sahloul
Sousse Tunisia
College of Medicine
Riyadh Saudi Arabia
Comenius University Medical School
Bratislava Slovakia
Dokuz Eylül Üniversitesi
Izmir Turkey
“Dr. Salvador Zubirán” National Institute of Medical Sciences and Nutrition
Tlalpan Mexico
Dr. Sami Ulus Maternity and Children Research and Training Hospital
Ankara Turkey
Ege Üniversitesi
Izmir Turkey
Faculdades Pequeno Príncipe
Curitiba Brazil
Faculté des Sciences Ben M’Sick
Casablanca Morocco
Hassan II University of Casablanca
Casablanca Morocco
Hôpital Necker Enfants Malades
Paris France
Hospital de Ninos Ricardo Gutierrez
Buenos Aires Argentina
Hospital de Ninos Sor Maria Ludovica
La Plata Argentina
Hospital de Ninos Víctor J. Vilela
Rosario Argentina
Hospital de Pediatria SAMIC Prof. Dr. Juan P. Garrahan
Buenos Aires Argentina
Hospital De San José, Bogotá, Colombia
Bogota Colombia
Hospital General O'Horan
Merida Mexico
Hospital Regional de Concepción
Concepcion Chile
Howard Hughes Medical Institute
Chevy Chase United States
Instituto Nacional de Pediatría
Mexico Mexico
Institut Pasteur - Alger
Algiers Algeria
Institut Pasteur de Tunis
Tunis Tunisia
King Fahad Medical City
Riyadh Saudi Arabia
l'Institut des Maladies Génétiques Imagine
Paris France
Marmara Üniversitesi
Istanbul Turkey
National Children's Hospital “Benjamín Bloom”
San Salvador El Salvador
National Research Institute of Tuberculosis and Lung Disease Tehran
Tehran Iran
Necmettin Erbakan Üniversitesi
Meram Turkey
Rockefeller University
New York United States
Tawam Hospital
Abu Dhabi United Arab Emirates
Universidade de São Paulo
Sao Paulo Brazil
Università degli Studi di Roma "Tor Vergata"
Rome Italy
Université Paris Cité
Paris France
Metrikler
112
Atıf
66
Yazar
5
Anahtar Kelime