Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Bacterial agents causing meningitis during 2013–2014 in Turkey: A multi-center hospital-based prospective surveillance study
Human Vaccines and Immunotherapeutics · Kasım 2016
YÖKSİS Kayıtları
Bacterial agents causing meningitis during 2013 2014 in Turkey A multi center hospital based prospective surveillance study
Human Vaccines Immunotherapeutics · 2016 SCI-Expanded
DOÇENT MELİKE EMİROĞLU →
Makale Bilgileri
DergiHuman Vaccines and Immunotherapeutics
Yayın TarihiKasım 2016
Cilt / Sayfa12 · 2940-2945
Scopus ID2-s2.0-84980335762
Erişim🔓 Açık Erişim
Özet
This is an observational epidemiological study to describe causes of bacterial meningitis among persons between 1 month and 18 y of age who are hospitalized with suspected bacterial meningitis in 7 Turkish regions. covering 32% of the entire population of Turkey. We present here the results from 2013 and 2014. A clinical case with meningitis was defined according to followings: any sign of meningitis including fever, vomiting, headache, and meningeal irritation in children above one year of age and fever without any documented source, impaired consciousness, prostration and seizures in those < 1 y of age. Single tube multiplex PCR assay was performed for the simultaneous identification of bacterial agents. The specific gene targets were ctrA, bex, and ply for N. meningitidis, Hib, and S. pneumoniae, respectively. PCR positive samples were recorded as laboratory-confirmed acute bacterial meningitis. A total of 665 children were hospitalized for suspected acute meningitis. The annual incidences of acute laboratory-confirmed bacterial meningitis were 0.3 cases / 100,000 population in 2013 and 0.9 cases/100,000 in 2014. Of the 94 diagnosed cases of bacterial meningitis by PCR, 85 (90.4%) were meningococcal and 9 (9.6%) were pneumococcal. Hib was not detected in any of the patients. Among meningococcal meningitis, cases of serogroup Y, A, B and W-135 were 2.4% (n = 2), 3.5% (n = 3), 32.9% (n = 28), and 42.4% (n = 36). No serogroup C was detected among meningococcal cases. Successful vaccination policies for protection from bacterial meningitis are dependent on accurate determination of the etiology of bacterial meningitis. Additionally, the epidemiology of meningococcal disease is dynamic and close monitoring of serogroup distribution is comprehensively needed to assess the benefit of adding meningococcal vaccines to the routine immunization program.
Yazarlar (36)
1
M. Ceyhan
2
Yasemin Ozsurekci
3
Nezahat Gurler
4
Eda Karadag Oncel
5
Yıldız Camcıoglu
6
Nuran Salman
7
Melda Celik
8
Melike Emiroglu
ORCID: 0000-0003-1307-0246
9
Fatih Akin
10
H. Tezer
11
Aslinur Ozkaya Parlakay
12
Nilden Tuygun
13
Diyar Tamburaci
14
Ener Cagri Dinleyici
15
Adem Karbuz
16
Ünal Uluca
17
Emre Alhan
18
Ümmühan Çay
19
Zafer Kurugöl
20
Nevin Hatipoglu
21
Rengin Siraneci
22
Tolga İnce
23
Gulnar Sensoy
24
Nursen Belet
25
Enes Coskun
26
Fatih Yilmaz
27
Mustafa Hacımustafaoğlu
28
Solmaz Çelebi
29
Umit Celik
30
Metehan Ozen
31
Aybüke Akaslan
32
Ilker Devrim
33
Necdet Kuyucu
34
Fatma Nur Öz
ORCID: 0000-0001-8374-095X
35
Sefika Elmas Bozdemir
ORCID: 0000-0003-1058-0320
36
Ahu Kara Aksay
Anahtar Kelimeler
epidemiology
etiologic agents
hospital surveillance
Meningitis
Turkey
Kurumlar
Adana Numune Training and Research Hospital
Adana Turkey
Akdeniz University, Faculty of Medicine
Antalya Turkey
Ankara Children's Hematology Oncology Training and Research Hospital
Ankara Turkey
Bursa Uludağ Üniversitesi
Bursa Turkey
Çukurova Üniversitesi Tip Fakültesi
Adana Turkey
Dicle University, Faculty of Medicine
Diyarbakir Turkey
Dr. Behçet Uz Children Research and Training Hospital
Izmir Turkey
Dr. Sami Ulus Children's Health and Diseases Training and Research Hospital
Ankara Türkiye
Ege University Medical School
Izmir Turkey
Elazığ University Faculty of Medicine
Elazig Turkey
Eskişehir Osmangazi Üniversitesi Tip Fakültesi
Eskisehir Turkey
Gaziantep Üniversitesi
Gaziantep Turkey
Gazi University, Faculty of Medicine
Ankara Turkey
Hacettepe Üniversitesi
Ankara Turkey
Istanbul Kanuni Sultan Suleyman Training and Research Hospital
Istanbul Türkiye
İstanbul Tıp Fakültesi
Istanbul Turkey
Istanbul Üniversitesi
Istanbul Turkey
Kayseri Training and Research Hospital
Kayseri Turkey
Konya Meram Training and Research Hospital
Konya Turkey
Mersin Üniversitesi
Mersin Turkey
Okmeydani State Hospital
Istanbul Turkey
Ondokuz Mayis University, Medical School
Samsun Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Süleyman Demirel University, Faculty of Medicine
Isparta Turkey
T.C. Sağlik BakanliğI, Sanliurfa Devlet Hastanesi
Sanliurfa Turkey
Tepecik Training and Research Hospital
Izmir Türkiye
Metrikler
30
Atıf
36
Yazar
5
Anahtar Kelime