Scopus
YÖKSİS Eşleşti
Association of depressive symptoms with 25(OH) vitamin D in hemodialysis patients and effect of gender
Clinical and Experimental Nephrology · Ocak 2020
YÖKSİS Kayıtları
Association of depressive symptoms with 25(OH) vitamin D in hemodialysis patients and effect of gender
Clinical and Experimental Nephrology · 2019 SCI-Expanded
PROFESÖR YASEMİN COŞKUN YAVUZ →
Association of depressive symptoms with 25(OH) vitamin D in hemodialysis patients and effect of gender
Clinical and Experimental Nephrology · 2020 SCI-Expanded
PROFESÖR ZEYNEP BIYIK →
Association of depressive symptoms with 25(OH) vitamin D in hemodialysis patients and effect of gender
Clinical and Experimental Nephrology · 2020 SCI-Expanded
PROFESÖR SEDAT ABUŞOĞLU →
Association of depressive symptoms with 25(OH) vitamin D in hemodialysis patients and effect of gender
Clinical and Experimental Nephrology · 2019 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ MUSLU KAZIM KÖREZ →
Makale Bilgileri
DergiClinical and Experimental Nephrology
Yayın TarihiOcak 2020
Cilt / Sayfa24 · 63-72
Scopus ID2-s2.0-85073926422
Özet
Background: Depression is common in chronic kidney disease (CKD) patients and associated with significant increase in morbidity and mortality. In recent years, a relationship between vitamin D deficiency and depression has been shown. The aim of this study is to investigate the relationship between 25-hydroxy (OH) vitamin D and depression in hemodialysis patients. Methods: A total of 140 patients were included in the study. Hamilton depression scale (HAM-D) was completed by all patients. 25(OH) vitamin D levels were compared between patients with and without depressive symptoms. Results: Patients who had depressive symptoms had significantly lower 25(OH) vitamin D levels (13.70 [24.3–8.25] vs. 18.20 [29.2–11.7] ng/mL, p = 0.016). HAM-D score showed significant association with gender (p = 0.011) and 25(OH) vitamin D level (p = 0.011). Univariate logistic regression analysis showed that males had lower risk of depression by a ratio of 61.1% (OR 0.389, p = 0.012) and vitamin D-deficient patients had 2.88 times greater risk of depression compared to non-deficient patients (OR 2.885, p = 0.013). Multivariate logistic regression analysis showed that males had 53.7% less risk of depression (OR 0.463, p = 0.046) and vitamin D-deficient patients had 2.39 times greater risk of depression (OR 2.397, p = 0.047). When evaluated by gender, univariate logistic regression analysis showed that 25(OH) vitamin D and other variables were not associated with depression in females (p > 0.05), while only vitamin D level had a significant effect on depression in males (OR 8.207, p = 0.008). Conclusions: We found a significant association between vitamin D level and depressive symptoms in hemodialysis patients. When analyzed according to gender, this association was found to stand independent of other variables only in males.
Yazarlar (9)
1
Yasemin Coşkun Yavuz
2
Zeynep Bıyık
3
Durmus Ozkul
4
Sedat Abusoglu
ORCID: 0000-0002-2984-0527
5
Duygu Eryavuz
6
Mikail Dag
7
M. K. Korez
ORCID: 0000-0001-9524-6115
8
Ibrahim Guney
9
Lütfullah Altıntepe
Anahtar Kelimeler
Depression
Gender
Hemodialysis
Vitamin D
Kurumlar
Konya Meram Training and Research Hospital
Konya Turkey
Selçuk Tip Fakültesi
Konya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
6
Atıf
9
Yazar
4
Anahtar Kelime