Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q4
The Effect of Size and Clinical Staging of Mammary Tumors on Blood Parameters in Bitches
Acta Scientiae Veterinariae · Ocak 2022
YÖKSİS Kayıtları
The Effect of Size and Clinical Staging of Mammary Tumors on Blood Parameters in Bitches
ACTA SCIENTIAE VETERINARIAE · 2022 SSCI
Dr. Öğr. Üyesi BEYZA SUVARIKLI ALAN →
The Effect of Size and Clinical Staging of Mammary Tumors on Blood Parameters in Bitches
Acta Scientiae Veterinariae · 2022 SCI-Expanded
Prof. Dr. VAHDETTİN ALTUNOK →
The Effect of Size and Clinical Staging of Mammary Tumors on Blood Parameters in Bitches
Acta Scientiae Veterinariae · 2022 SCI-Expanded
Doç. Dr. FATMA SATILMIŞ →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Bovine Leukemia Virus Antibodies in Dairy Cattle Farms and Milk Cooling Tanks
2014 ISSN: 1678-0345 SCI-Expanded
Prof. Dr. OĞUZHAN AVCI →
Effect of CorynebacteriumcutisLysate on Serum Oxidative Stressand Plasma Prostaglandin F2 Metabolite Levels
2014 ISSN: 1678-0345 SCI-Expanded
Prof. Dr. BURAK DİK →
Hepatoprotective Effects of Ginseng in Rats Fed Cholesterol Rich Diet
2016 ISSN: 1678-0345 SCI-Expanded
Prof. Dr. ERCAN KESKİN →
Effect of Anti TNF on the Development of Offspringand Pregnancy Loss During Pregnancy in Rats
2016 ISSN: 1678-0345 SCI-Expanded
Prof. Dr. AYŞE ER →
Investigation of the Effect of Tarantula cubensis Extract on Acute Phase Response
2016 ISSN: 1678-0345 SCI-Expanded
Prof. Dr. AYŞE ER →
Detection of Antibodies against Equine Herpes Virus 1and Equine Herpes Virus 4 in Horses in Southeast Anatolia by Indirect Elisa
2014 ISSN: 1678-0345 SCI-Expanded
Prof. Dr. OĞUZHAN AVCI →
Hepatoprotective Effects of Ginseng in Rats Fed Cholesterol Rich Diet
2016 ISSN: 1678-0345 SCI-Expanded
Prof. Dr. DENİZ ULUIŞIK →
Investigation of the Effect of Tarantula cubensis Extract on Acute Phase Response
2016 ISSN: 1678-0345 SCI-Expanded
Prof. Dr. BURAK DİK →
Effect of Anti TNF-a on the Development of Offspringand Pregnancy Loss During Pregnancy in Rats
2016 ISSN: 1678-0345 SCI-Expanded
Prof. Dr. BURAK DİK →
Amiodarone May Prevent the Tilmicosin caused Lethal Toxicity
2014 ISSN: 1678-0345 SCI-Expanded
Prof. Dr. BÜNYAMİN TRAŞ →
Effect of Hoof Trimming on Milk Yield in Dairy Cows with Foot Disease
2016 ISSN: 1678-0345 SCI-Expanded
Prof. Dr. TAMER ÇAĞLAYAN →
Bovine coronavirus (BoCV) infection in calves with diarrhoea and their dams
2016 ISSN: 1678-0345 SCI-Expanded
Prof. Dr. ORHAN YAPICI →
The Effects of Coenzyme Q10 on Inflammation Markers in Streptozotocin-Induced Diabetic Rats
2017 ISSN: 1678-0345 SCI-Expanded
Prof. Dr. ERCAN KESKİN →
The Effects of Coenzyme Q10 on Inflammation Markersin Streptozotocin-Induced Diabetic Rats
2017 ISSN: 1678-0345 SCI-Expanded
Prof. Dr. DENİZ ULUIŞIK →
Comparison of the Effectiveness of Halofuginone Lactate and Paromomycin in the Treatment of Calves Naturally Infected with Cryptosporidium parvum
2018 ISSN: 1678-0345 SCI-Expanded
Prof. Dr. NERMİN IŞIK USLU →
Safety of antitheilerial drug buparvaquone in rams
2018 ISSN: 1678-0345 SCI-Expanded Q4
Prof. Dr. NERMİN IŞIK USLU →
Pentoxifylline May Restore Kanamycin-Induced Renal Damage in Rats
2018 ISSN: 1678-0345 SCI-Expanded
Prof. Dr. ÖZGÜR ÖZDEMİR →
Comparison of the Effectiveness of Halofuginone Lactate and Paromomycin in the Treatment of Calves Naturally Infected with Cryptosporidium parvum
2018 ISSN: 1678-0345 SCI-Expanded
Prof. Dr. ÖZLEM DERİNBAY EKİCİ →
Comparison of Thermographic Imaging and Other Diagnostic Techniques in Diagnosis of Cattle with Laminitis
2018 ISSN: 1678-0345 SCI-Expanded
Prof. Dr. FATİH HATİPOĞLU →
Bovine Coronavirus (BoCV) Infection in Calves with Diarrhoea and Their Dams
2018 ISSN: 1678-0345 SCI-Expanded
Prof. Dr. OĞUZHAN AVCI →
Makale Bilgileri
ISSN16780345
Yayın TarihiOcak 2022
Cilt / Sayfa50
Scopus ID2-s2.0-85180423830
Erişim🔓 Açık Erişim
Özet
Background: Mammary tumors are the most common type of tumor in female dogs and account for 50% of all tumors in dogs. The clinical prognosis of canine mammary tumors is strongly affected by the size, stages, histological type, and grade of tumor; mitotic index; and nearby and distant metastasis. In canine mammary tumors, it is recommended that prognostic evaluation should also include complete blood count, serum biochemistry, and blood gases in addition to tumor size and stage. This study aimed to investigate the effect of tumor size, volume, and clinical stage on complete blood count, blood gas analysis, and serum biochemical parameters in bitches with mammary tumors and the correlation between them. Materials, Methods & Results: The study included a total of 18 bitches of different breeds, aged 6-15 years, of which 12 had mammary tumors and 6 were healthy. Thoracic X-rays were performed on bitches with mammary tumors in ventrodorsal and laterolateral positions to evaluate lung metastasis. Blood samples were collected from the cephalic vein from bitches in both groups in 2 different tubes (with plastic gel and ethylenediaminetetraacetic acid), 5 mL each, to perform complete blood count and evaluate blood gases and serum biochemical parameters. Blood samples were collected from the animals at the time of initial examination without any intervention. Analysis of the blood showed that bitches with mammary tumors had decreased levels of RBC, HCT, HGB, potassium, TCO2, base excess, THbc, and ALT enzyme activity and increased levels of lactate, total protein, cholesterol, triglyceride, LDL, uric acid, and ALP and LDH enzyme activities compared with those in the control group. Furthermore, the dogs with a primary tumor of > 5 cm were found to have significantly higher levels of WBC, lactate, total protein, triglyceride, LDL, uric acid, and ALP and LDH enzyme activities and significantly lower levels of RBC and THbc compared with those in the control group. Bitches with tumors in multiple mammary lobes were found to have significantly higher levels of WBC, total protein, triglyceride, LDL, and ALP and LDH enzyme activities and significantly lower levels of RBC, HCT, HGB, TCO2, THbc, and ALT enzyme activity compared with those in the control group. Based on the laboratory findings and approval of the owners of the dogs, mammary tissues containing the tumor and lymph nodes were surgically removed. After the operation, the removed mammary tissues were evaluated for size and volume. Clinical staging of the tumors was performed based on the size of the primary tumor (T), nearby lymph nodes (N), and metastasis (M) in accordance with the criteria set by WHO. Clinical staging of the tumors was, thus, based on the tumor, nodes, and metastases (TNM) score obtained according to the following system: Stage I: T1N0M0, Stage II: T2N0M0, Stage III: T3N0M0, Stage IV: TanyN1M0, Stage V: made as TanyNanyM1. Discussion: Mammary tumors are the most common type of neoplasm in bitches and, thus, cause serious problems in veterinary medicine. Tumors are significantly correlated with better prognosis compared with larger tumors. Based on this finding, this study investigated the effect of size, volume, and stage of mammary tumors in bitches on some blood parameters and the correlation between them. Therefore, it was concluded that clinical staging and evaluation of blood parameters could be useful in the diagnosis, treatment, and prediction of prognosis in canine mammary tumors. This study found that bitches with mammary tumors exhibited significant changes in their blood parameters (complete blood count, blood gas analysis, and serum biochemistry). The results obtained from this study may contribute to the development of approaches to the diagnosis, prediction of prognosis, and treatment of canine mammary tumors.
Yazarlar (7)
1
Fatma Satilmiş
2
Beyza S. Alan
ORCID: 0000-0003-4698-9291
3
V. Altunok
4
M. B. Kivrak
5
Mert Demirsöz
6
Hasan Alkan
ORCID: 0000-0001-8332-5334
7
Ibrahim Aydin
Anahtar Kelimeler
blood gas analysis
complete blood count
dogs
mammary tumor
serum biochemistry
tumor volume
Kurumlar
Cumhuriyet Üniversitesi
Sivas Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Acta Scientiae Veterinariae
Q4
SJR Skoru0,155
H-Index20
YayıncıUniversidade Federal do Rio Grande do Sul
ÜlkeBrazil
Veterinary (miscellaneous) (Q4)
Metrikler
2
Atıf
7
Yazar
6
Anahtar Kelime