Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q2
The effects of Capparis ovata seed oil on the healing of traumatic skin wounds
Ulusal Travma Ve Acil Cerrahi Dergisi · Eylül 2022
YÖKSİS Kayıtları
The effects of Capparis ovata seed oil on the healing of traumatic skin wounds
ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY · 2022 SCI-Expanded
Dr. Öğr. Üyesi MUSLU KAZIM KÖREZ →
YÖKSİS Kayıtları — ISSN Eşleşmesi
The effects of methylene blue on adhesion formation in a rat model of experimental peritonitis
2011 ISSN: 1306696X SCI-Expanded
Prof. Dr. CEYHAN UĞURLUOĞLU →
Epidemiologic Evaluation of Patients with Major Burns and Recommendations for Fighting with Burns
2012 ISSN: 1306696X SCI-Expanded
Prof. Dr. İLHAN ÇİFTCİ →
Epidemiologic Evaluation of Patients with Major Burns and Recommendations for Fighting with Burns
2012 ISSN: 1306696X SCI-Expanded
Prof. Dr. FATİH KARA →
Epidemiologic evaluation of patients with major burns and recommendations for burn prevention.
2012 ISSN: 1306-696X SCI-Expanded
Prof. Dr. HÜSEYİN YILMAZ →
Isolated axillary artery injury due to blunt trauma
2007 ISSN: 1306-696X SCI-Expanded 4 atıf
Prof. Dr. MEHMET ALKILIÇ HORASANI ÖÇ →
An evaluation of the relationship between blood glucose level and prognosis in acute phase of head injuries
2004 ISSN: 1306696X SCI-Expanded
Prof. Dr. AHMET AK →
Is Total-subtotal Colectomy and Primary Anastomosis Good Treatment Alternatives in Malignant Obstructive Lesions of the Left Colon?
2012 ISSN: 1306696X TR DİZİN
Prof. Dr. HANDE KÖKSAL →
Total oxidant status, total antioxidant status, and paraoxonase activity in acute appendicitis
2015 ISSN: 1306696X SCI-Expanded
Prof. Dr. HANDE KÖKSAL →
Predictive value of preoperative neutrophil-to-lymphocyte ratio while detecting bowel resection in hernia with intestinal incarceration
2018 ISSN: 1306-696X SCI-Expanded
Prof. Dr. HANDE KÖKSAL →
The reconstruction of soft tissue defects in the elbow area: a treatment algorithm proposal
2009 ISSN: 1306-696X TR DİZİN
Prof. Dr. ZEKERİYA TOSUN →
Posterior Interosseous Flap versus Reverse Adipofascial Radial Forearm Flap For Soft Tissue reconstruction Of Dorsal Hand Defects
2018 ISSN: 1306-696X SCI-Expanded Q4
Doç. Dr. GÖKÇE YILDIRAN →
The effect of nitroglycerin in the zone of stasis in a rat burn model
2020 ISSN: 1306-696X SCI-Expanded
Prof. Dr. CEYHAN UĞURLUOĞLU →
The effects of nitroglycerin in the zone of stasis in a ratburn model
2020 ISSN: 1306-696X SCI-Expanded
Prof. Dr. TAMER SEKMENLİ →
High-pressure injection injuries to the upper extremity and the review of the literature
2020 ISSN: 1306-696X SCI-Expanded
Prof. Dr. ZEKERİYA TOSUN →
Influence of galantamine on peripheral nerve degeneration after experimental compression injury of the rat sciatic nerve
2020 ISSN: 1306-696X SCI-Expanded
Doç. Dr. MERT ŞAHİNOĞLU →
Role of ultrasound simulators in the training for Focused Assessment with Sonography for Trauma (FAST)
2021 ISSN: 1306-696X SCI Q4
Prof. Dr. HASAN KARA →
Role of ultrasound simulators in the training for Focused Assessment with Sonography for Trauma (FAST)
2021 ISSN: 1306-696X SCI-Expanded
Prof. Dr. AHMET AK →
Evaluating incorrect management of transferred pediatric burn patients
2016 ISSN: 1306-696X SCI-Expanded Q4
Doç. Dr. FATMA ÖZCAN SIKI →
High-pressure injection injuries to the upper extremity and the review of the literature
2020 ISSN: 1306-696X SCI-Expanded Q4
Doç. Dr. GÖKÇE YILDIRAN →
Influence of galantamine on peripheral nerve degeneration after experimental compression injury of the rat sciatic nerve
2022 ISSN: 1306-696X SCI
Doç. Dr. MERT ŞAHİNOĞLU →
Makale Bilgileri
ISSN1306696X
Yayın TarihiEylül 2022
Cilt / Sayfa28 · 1205-1313
Scopus ID2-s2.0-85137137431
Erişim🔓 Açık Erişim
Özet
BACKGROUND: Capparis ovata contains alkaloids, lipids, polyphenols, flavonoids, and also is rich in antioxidants. Conventionally, in Turkey, the flower buds, root, bark, and fruits of C. ovata are used for their analgesic, anti-inflammatory, anti-rheumatism, tonic, and diuretic effects. The aim of this study was to examine the effect on wound healing of C. ovata seed oil (COSO), which is known to have antioxidant, anti-inflammatory, and antibacterial properties. METHODS: In the study, 20 Wistar albino female rats were randomly divided into two groups of 10 animals each. A standard full-thickness skin defect was created on the back area of the rats. In both groups, after cleaning the wounds with saline daily, no active substance other than saline was applied to the control group, while 1 cc/day COSO was applied to the wounds of the rats in the study group. On the post-operative 14th day, the rats were reanesthetized and wound area measurements were made. Then, excision was performed to include 1 cm of intact tissue around the wound, which remained unhealed, and samples were taken for histopathological examination. RESULTS: The changes in wound areas showed that after 14 days, the improvement in the group treated with caper oil (32.78; 95% confidence interval, 17.21–48.36) was significantly higher than that of the control group (65.41; 95% confidence interval, 49.84–80.98) (p=0.009). The histopathological scores showed a significant difference between the groups in respect of epithelial formation, inflammation, and fibrosis development. No epithelial tissue formation was observed in the control group (90%), and more incomplete re-epithelization and focal epidermal hyperplasia were observed in the treatment group (60%). Fibrosis development was mild and weak (70%) in the control group and was evaluated as severe and intense (60%) in the treatment group. Perivascular edema was mild (50%) and vascularity was immature (60% – an indicator of neovascularization) in the treatment group. These histopathological results showed that the treatment group inflammation phase was completed and the proliferation phase started, as well as the effectiveness of the use of caper oil on epithelization, angiogenesis, and fibrosis, which are important histopathological parameters in the evaluation of wound healing compared to the control group. CONCLUSION: From the results of this study, it was concluded that COSO significantly enhances the healing of full-thickness skin wounds and this effect is primarily related to its anti-inflammatory effect.
Yazarlar (10)
1
Salih Celepli
2
Bayram Çolak
3
Ümran Aydemir Sezer
4
Pınar Celepli
5
İrem Bigat
6
Mehmet Esat Duymuş
7
M. K. Korez
ORCID: 0000-0001-9524-6115
8
Sema Hücümenoğlu
9
Kemal Kısmet
10
Mustafa Şahin
Anahtar Kelimeler
Anti-inflammatory
Capparis ovata seed oil
skin
traumatic
wound healing
Kurumlar
Ankara Numune Education and Research Hospital
Ankara Turkey
Gülhane Eğitim ve Araştırma Hastanesi
Ankara Turkey
Mustafa Kemal Üniversitesi
Antakya Turkey
Selçuk Tip Fakültesi
Konya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Süleyman Demirel University, Faculty of Medicine
Isparta Turkey
TOBB University of Economics and Technology
Ankara Turkey
University of Health Sciences
Istanbul Turkey
Scimago Dergi (ISSN Eşleşmesi)
Ulusal Travma ve Acil Cerrahi Dergisi
Q2
SJR Skoru0,377
H-Index33
YayıncıTurkish Association of Trauma and Emergency Surgery
ÜlkeTurkey
Emergency Medicine (Q2)
Anesthesiology and Pain Medicine (Q3)
Surgery (Q3)
Metrikler
4
Atıf
10
Yazar
5
Anahtar Kelime