Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q3
Short-and long-term neurological outcomes of congenital cytomegalovirus infection
Turkish Journal of Medical Sciences · Ocak 2024
YÖKSİS Kayıtları
Short- and long-term neurological outcomes of congenital cytomegalovirus infection
Turkish Journal of Medical Sciences · 2024 SSCI
Dr. Öğr. Üyesi FATİH MEHMET AKİF ÖZDEMİR →
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2012 ISSN: 1300-0144 SCI-Expanded
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2015 ISSN: 13000144 SCI-Expanded
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2014 ISSN: 13000144 SCI-Expanded
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2014 ISSN: 1300-0144 SCI-Expanded
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Pregnancy associated plasma protein A and procalcitonin as markers of myocardial injury in patients with acute coronary syndrome
2015 ISSN: 13000144 SCI-Expanded
Prof. Dr. AYŞEGÜL BAYIR →
Comparison of the efficacy of prednisolone montelukast and omalizumab in an experimental allergic rhinitis model
2014 ISSN: 13000144 SCI-Expanded
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2016 ISSN: 1300-0144 SCI-Expanded
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Makale Bilgileri
ISSN13000144
Yayın TarihiOcak 2024
Cilt / Sayfa54 · 529-536
Scopus ID2-s2.0-85197404531
Erişim🔓 Açık Erişim
Özet
Background/aim: Cytomegalovirus (CMV) is the most common congenital viral infection. Although most children with congenital CMV (approximately 85%–90%) are asymptomatic at birth, findings such as sensorineural hearing loss, microcephaly, and neurodevelopmental retardation can be observed during the follow-up. Among the brain magnetic resonance imaging (MRI) findings of CMV are white matter abnormalities, polymicrogyria, and periventricular calcification. Since a definitive diagnosis of congenital CMV cannot be made after the neonatal period, the identification of the associated phenotype is diagnostically important, but data are limited in patients who have been retrospectively diagnosed with congenital CMV infection. The aim of this study was to evaluate the short-and long-term neurological follow-up results of congenital CMV infections in a tertiary hospital. Materials and methods: The neurological results of fifteen patients under the age of 18 years, who had a definitive diagnosis of congenital CMV infection and were followed up in a tertiary care hospital between 2011 and 2020, were retrospectively evaluated. Results: Ten of the patients in our study group were male. The mean age at presentation for neurological evaluation was 2.02 ± 1.54 months, with a median follow-up time of 36.3 months (range: 9.3–129.4 months). Neurological disorders detected during the long-term follow-up included cerebral palsy (46.7%), cognitive impairment (46.7%), epilepsy (40%), and sensorineural hearing loss (26.7%). The most common abnormality observed on MRI scans was white matter involvement (53.3%). Conclusion: Early diagnosis and intervention are crucial in congenital CMV infection, as it commonly results in neurological involvement among the patients in our series. This preventable condition warrants further research regarding prenatal/neonatal screening.
Yazarlar (5)
1
Fatih Mehmet Akif Özdemir
ORCID: 0000-0003-4820-1234
2
Yasemin Taşçi Yildiz
ORCID: 0000-0003-4639-2081
3
Rüveyda Gümüşer Cinni
ORCID: 0000-0002-6373-2589
4
Ayşegül Zenciroğlu
ORCID: 0000-0002-3488-4962
5
Deniz Yüksel
ORCID: 0000-0001-8990-023X
Anahtar Kelimeler
Congenital cytomegalovirus infection
magnetic resonance imaging
neurologic outcomes
Kurumlar
University of Health Sciences
Istanbul Turkey
Scimago Dergi (ISSN Eşleşmesi)
Turkish Journal of Medical Sciences
Q3
SJR Skoru0,386
H-Index44
YayıncıTUBITAK
ÜlkeTurkey
Medicine (miscellaneous) (Q3)
Metrikler
3
Atıf
5
Yazar
3
Anahtar Kelime