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Scopus YÖKSİS DOI Eşleşti SJR Q2

Sericin and gentamicin-enhanced polyurethane-acrylate adhesives for superior adhesion, biocompatibility and antibacterial property

International Journal of Adhesion and Adhesives · Mayıs 2025

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YÖKSİS Kayıtları
Sericin and gentamicin-enhanced polyurethane-acrylate adhesives for superior adhesion, biocompatibility and antibacterial property
International Journal of Adhesion and Adhesives · 2025 SCI-Expanded
Dr. Öğr. Üyesi MERVE GÖKŞİN KARAASLAN TUNÇ →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 5 kaydı bulundu.

YÖKSİS Kayıtları — ISSN Eşleşmesi
Biodegradable non-aromatic adhesive polyurethanes based on disaccharides for medical applications
2014 ISSN: 0143-7496 SCI
Dr. Öğr. Üyesi MERVE GÖKŞİN KARAASLAN TUNÇ →
Biomimetic approach to tunable adhesion of polyurethane adhesives through Fe3 crosslinking and hydrophobic tween units with balance of adhesion/cohesion forces
2019 ISSN: 0143-7496 SCI-Expanded
Dr. Öğr. Üyesi MERVE GÖKŞİN KARAASLAN TUNÇ →
The mussel-inspired polydopamine surface treatment influences bond strength of glass fiber posts to radicular dentin
2021 ISSN: 0143-7496 SCI-Expanded Q2
Prof. Dr. SEMA BELLİ →
An experimental assessment of hybrid bolted/bonded basalt fiber reinforced polymer composite joints' temperature-dependent mechanical performances by static and dynamic mechanical analyses
2022 ISSN: 0143-7496 SCI-Expanded Q2
Doç. Dr. HASAN ULUS →
Sericin and gentamicin-enhanced polyurethane-acrylate adhesives for superior adhesion, biocompatibility and antibacterial property
2025 ISSN: 0143-7496 SCI-Expanded Q2
Dr. Öğr. Üyesi MERVE GÖKŞİN KARAASLAN TUNÇ →

Makale Bilgileri

Dergi International Journal of Adhesion and Adhesives
ISSN01437496
Yayın TarihiMayıs 2025
Cilt / Sayfa139
DOI10.1016/j.ijadhadh.2025.103988
Scopus ID2-s2.0-85217890508
Özet Bioadhesives are crucial in minimally invasive procedures but often lack biocompatibility, mechanical strength, and antimicrobial properties. Polyurethane-based adhesives, particularly UV-curable types, offer tunable properties and rapid curing. This study developed a polyurethane-acrylate adhesive system incorporating sericin and gentamicin to enhance biocompatibility and antibacterial effects for surgical and wound care applications. Sericin, a silk-derived protein, improved cell adhesion without compromising structural integrity, while 2.5 % gentamicin provided sustained antibacterial activity against E. coli, P. aeruginosa, and S. aureus. The synthesis involved modifying IPDI with β-cyclodextrin, sericin, and PEG (200, 400, 600) to optimize flexibility and stability. Comprehensive characterization was conducted, including FTIR, TGA, DSC, NMR, SEM, AFM, adhesion strength, biodegradability, gentamicin release, antibacterial efficacy, and biocompatibility with L-929 fibroblast cells. Adhesion strengths were 4141.3–4474.7 kPa (PEG200), 2306–3158 kPa (PEG400), and 1690–2061 kPa (PEG600), with PEG400 providing the best balance, making IPDI-SER-P400-20-AC the optimal candidate. The adhesive exhibited 87 % cell viability (ISO 10993-5), 30 % biodegradation in four weeks, and 60 % gentamicin release within 24 h, ensuring rapid antibacterial action. This sericinand gentamicin-enhanced bioadhesive offers a promising multifunctional platform for biomedical applications, with potential for further optimization in controlled drug release and long-term in vivo evaluations.

Yazarlar (8)

1
Sevgi Balcioglu
ORCID: 0000-0003-0724-4772
2
Merve Gökşin Karaaslan
3
Ahmet Ulu
ORCID: 0000-0002-4447-6233
4
Imren Ozcan
5
Samir Abbas Ali Noma
ORCID: 0000-0003-4165-0045
6
Canbolat Gürses
ORCID: 0000-0002-4085-0224
7
Burhan Ates
ORCID: 0000-0001-6080-229X
8
Suleyman Koytepe
ORCID: 0000-0002-4788-278X

Anahtar Kelimeler

Antibacterial Biocompatibility Gentamicin Polyurethane-acrylate adhesives Sericin

Kurumlar

Bursa Uludağ Üniversitesi
Bursa Turkey
Inönü Üniversitesi
Malatya Turkey
Sakarya University of Applied Sciences
Serdivan Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
International Journal of Adhesion and Adhesives
Q2
SJR Skoru0,710
H-Index122
YayıncıElsevier Ltd
ÜlkeUnited Kingdom
Biomaterials (Q2)
Chemical Engineering (miscellaneous) (Q2)
Polymers and Plastics (Q2)
Dergi sayfasına git

Metrikler

5
Atıf
8
Yazar
5
Anahtar Kelime

Sistemimizdeki Yazarlar

MK
MERVE GÖKŞİN KARAASLAN TUNÇ
Dr. Öğr. Üyesi

Hızlı Erişim

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