Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Concentrations of serum amyloid A, haptoglobin, tumour necrosis factor and interleukin-1 and -6 in Anatolian buffaloes naturally infected with dermatophytosis
Veterinarni Medicina · Ocak 2016
YÖKSİS Kayıtları
Concentrations of serum amyloid A haptoglobin tumour necrosis factor and interleukin 1 and 6 in Anatolian buffaloes naturally infected with dermatophytosis
Veterinární Medicína · 2016 SCI-Expanded
PROFESÖR ZAFER SAYIN →
Makale Bilgileri
DergiVeterinarni Medicina
Yayın TarihiOcak 2016
Cilt / Sayfa61 · 133-135
Scopus ID2-s2.0-84962541616
Erişim🔓 Açık Erişim
Özet
Dermatophytosis is most frequently found in ruminants, in which non-pruritic periocular lesions are most typical, though generalised skin disease may develop. Accordingly, the infection causes major economic losses. The aim of this study was to measure the inflammatory status of Anatolian buffaloes with dermatophytosis by determining the serum concentrations of serum amyloid A (SAA), haptoglobin (Hp), tumour necrosis factor (TNF-α) and interleukin-1 (IL-1) and -6 (IL-6). Anatolian buffaloes (n = 26), aged three to 11 month, were divided into two groups: 11 animals served as the clinically healthy control group and 15 animals clinically and microbiologically diagnosed with dermatophytosis formed the experimental group. Concentrations of tested proteins were measured using commercially available ELISA kits. In all cases, concentrations of measured proteins were significantly higher (P < 0.05) in infected animals when compared to healthy controls: SAA: 41.05 ± 0.01 vs. 7.43 ± 0.11μg/ml; Hp: 96.21 ± 0.18 vs. 8.49 ± 0.79 μg/ml; TNF-α: 0.90 ± 0.99 vs. 0.10 ± 0.26 ng/ml; IL-1α: 186.22 ± 0.22 vs. 74.04 ± 0.90 pg/ml; and IL-6: 55.94 ± 0.50 vs. 32.45 ± 0.20 pg/ml. It was concluded that the elevated values of variables under study were a result of the inflammatory response to dermatophytosis; thus, these markers may serve as an additional diagnostic tool.
Yazarlar (2)
1
Mustafa Kabu
2
Zafer Sayın
Anahtar Kelimeler
Anatolian buffaloes
Cytokines
Dermatophytosis
Haptoglobin
Serum amyloid A
Kurumlar
Afyon Kocatepe Üniversitesi
Afyonkarahisar Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
9
Atıf
2
Yazar
5
Anahtar Kelime