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Scopus 🔓 Açık Erişim YÖKSİS DOI Eşleşti SJR Q3

Proliferation effects of phenylboronic acid and boric acid on canine peripheral blood mononuclear cells

Turkish Journal of Veterinary and Animal Sciences · Ocak 2019

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YÖKSİS Kayıtları
Proliferation effects of phenylboronic acid and boric acid on canine peripheral blood mononuclear cells
TURKISH JOURNAL OF VETERINARY ANIMAL SCIENCES · 2019 SCI-Expanded
Prof. Dr. UÇKUN SAİT UÇAN →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 20 kaydı bulundu.

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Makale Bilgileri

ISSN13000128
Yayın TarihiOcak 2019
Cilt / Sayfa43 · 229-234
Erişim🔓 Açık Erişim
Özet The effects of phenylboronic acid (PBA) and boric acid (BA) on the proliferation of canine peripheral blood mononuclear cells (PBMCs) were investigated. Treatment of PBMCs from mixed breed dogs with PBA or BA (0.05 µg/mL) alone elicited blastogenic responses of 0.478 ± 0.438 and 0.499 ± 0.366, respectively. We observed an additive effect on proliferation when purebred Kangal PBMCs were cultured in a combination of BA (0.001 µg/mL) and the mitogenic lectin concanavalin A (1 µg/mL). However, the effects were not statistically significant. We detected varied IL-2 and IL-4 secretion in response to stimulation with boron-containing compounds. Our findings suggest that PBA induces canine PBMC proliferation, albeit less potently than lectins. However, boronic acid compounds may still prove beneficial as adjuvants to elicit cell proliferation and boost canine immune responses.

Yazarlar (2)

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Uçkun Sait Uçan
2
Zafer Sayın

Anahtar Kelimeler

Boric acid Canine Mitogen Phenylboronic acid Proliferation

Kurumlar

Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Turkish Journal of Veterinary and Animal Sciences
Q3 OA
SJR Skoru0,256
H-Index46
YayıncıTUBITAK
ÜlkeTurkey
Veterinary (miscellaneous) (Q3)
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Metrikler

3
Atıf
2
Yazar
5
Anahtar Kelime

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