Scopus
YÖKSİS Eşleşti
Diagnostic effectiveness of stress biomarkers in cats with feline interstitial and bacterial cystitis
Veterinary Clinical Pathology · Mart 2023
YÖKSİS Kayıtları
Diagnostic effectiveness of stress biomarkers in cats with feline interstitial and bacterial cystitis
VETERINARY CLINICAL PATHOLOGY · 2022 SCI
PROFESÖR MEHMET MADEN →
Diagnostic eff ectiveness of stress biomarkers incats with feline interstitial and bacterial cystitis
VETERINARY CLINICAL PATHOLOGY · 2023 SCI-Expanded
PROFESÖR ZAFER SAYIN →
Diagnostic effectiveness of stress biomarkers in cats with feline interstitial and bacterial cystitis
VETERINARY CLINICAL PATHOLOGY · 2023 SCI-Expanded
PROFESÖR ZAFER SAYIN →
Diagnostic effectiveness of stress biomarkers in cats with feline interstitial and bacterial cystitis
Veterinary Clinical Pathology · 2023 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ TUĞBA MELİKE PARLAK →
Diagnostic effectiveness of stress biomarkers in cats with feline interstitial and bacterial cystitis
Veterinary Clinical Pathology · 2022 SCI-Expanded
PROFESÖR MEHMET MADEN →
Makale Bilgileri
DergiVeterinary Clinical Pathology
Yayın TarihiMart 2023
Cilt / Sayfa52 · 88-96
Scopus ID2-s2.0-85142771176
Özet
Background: Although bacterial cystitis (BC) and feline interstitial cystitis (FIC) are categorized under feline lower urinary tract disease (FLUTD) due to their similar clinical manifestations, stress is an important factor for FIC. Therefore, the investigation of stress biomarkers might be important in the differentiation and elucidation of these conditions. Objectives: We aimed to evaluate the diagnostic effectiveness of serum and urine cortisol, serotonin, and dopamine concentrations and their relationship with stress in cats with FIC and BC. Methods: Twelve healthy cats (Control group) and 24 cats with FLUTD were used. The cats with FLUTD were divided into FIC and BC groups. Results: Multimodal environmental modification (MEMO) scores were found to be higher in the FIC group than in the BC and Control groups (P <.001). Urine serotonin concentrations were higher in cats with FIC and BC compared with those in the Control group. Based on ROC analyses, the sensitivity, specificity, and accuracy of urine serotonin and dopamine were found to be statistically significant in being able to differentially diagnose cats in the FIC group vs the Control group. The sensitivity, specificity, and accuracy of serum dopamine were also found to be statistically significant for the differential diagnosis of FIC and BC. Conclusions: High urine serotonin concentrations were found in cats with FLUTD compared with healthy controls and interpreted as the presence of stress not only in cats with FIC but also in cats with BC. Also, based on the ROC-based diagnostic performance evaluation of these stress biomarkers, urine serotonin, and dopamine concentrations can be used to diagnose FIC, and serum dopamine concentrations can be used to differentiate FIC and BC in cats.
Yazarlar (4)
1
Erdem Gülersoy
ORCID: 0000-0001-8511-0150
2
Mehmet Maden
3
T. M. Parlak
4
Zafer Sayın
Anahtar Kelimeler
cat
cortisol
dopamine
serotonin
serum
urine
Kurumlar
Harran Üniversitesi
Sanliurfa Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
1
Atıf
4
Yazar
6
Anahtar Kelime