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Increased uncoupling protein 1 levels are associated with attention deficit and hyperactivity disorder in medication-free children

Journal of Psychiatric Research · Aralık 2022

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YÖKSİS Kayıtları
Increased uncoupling protein 1 levels are associated with attention deficit and hyperactivity disorder in medication-free children
Elsevier BV · 2022 SCI-Expanded
PROFESÖR HÜSAMETTİN VATANSEV →
Increased uncoupling protein 1 levels are associated with attention deficit and hyperactivity disorder in medication-free children
Elsevier BV · 2022 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ MUSTAFA ESAD TEZCAN →
Increased uncoupling protein 1 levels are associated with attention deficit and hyperactivity disorder in medication-free children
JOURNAL OF PSYCHIATRIC RESEARCH · 2022 SCI-Expanded
PROFESÖR HÜSAMETTİN VATANSEV →

Makale Bilgileri

DergiJournal of Psychiatric Research
Yayın TarihiAralık 2022
Cilt / Sayfa156 · 437-443
Özet Objective: This study aimed to investigate serum visfatin, irisin, and uncoupling protein 1 (UCP1) levels between children with attention deficit and hyperactivity disorder (ADHD) and healthy controls and to discuss how performance on the Stroop Color Test and Serial Digit Learning Test changes with these adipokines. Methods: A total of 45 medication-free children with ADHD and 43 controls aged 8–12 years were enrolled in this study. The serum levels of visfatin, UCP1, and irisin were measured using enzyme-linked immunosorbent assay kits. Results: As a result, in our study, a statistically significant difference was found in UCP1 in the ADHD group compared with the control group, but no significant difference was found in visfatin and irisin levels. An analysis of covariance was also performed for the whole sample, and when controlling for potential confounders, including body mass index, age, and gender, the results did not change. In addition, it was determined that adipokines did not correlate with neuropsychological tests. Conclusion: These findings suggest that UCP1 might be associated with childhood ADHD.

Yazarlar (3)

1
Mustafa Esad Tezcan
ORCID: 0000-0001-8362-1934
2
Halit Necmi Uçar
ORCID: 0000-0002-2706-7454
3
Hüsamettin Vatansev

Anahtar Kelimeler

Attention deficit hyperactivity disorder Executive functions Irisin UCP1 Visfatin

Kurumlar

Konya City Hospital
Konya Turkey
Selçuk Tip Fakültesi
Konya Turkey

Metrikler

2
Atıf
3
Yazar
5
Anahtar Kelime