Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
The evaluation of cardiovascular risk parameters using multiplex immunoassay inwomen with primary hyperlipiemia and obese hyperlipidemicwomen
Turkiye Klinikleri Journal of Medical Sciences · Ocak 2019
YÖKSİS Kayıtları
The Evaluation of Cardiovascular Risk Parameters Using Multiplex Immunoassay in Women with Primary Hyperlipiemia and Obese HyperlipidemicWomen
Turkiye Klinikleri Journal of Medical Sciences · 2019 EMBASE, Scopus, EBSCO/CINAHL tam metin Index ,Copernicus Chemical Abstracts Service (CAS), ProQuest
PROFESÖR FATMA HÜMEYRA YERLİKAYA AYDEMİR →
Makale Bilgileri
DergiTurkiye Klinikleri Journal of Medical Sciences
Yayın TarihiOcak 2019
Cilt / Sayfa39 · 319-327
Scopus ID2-s2.0-85073742594
Erişim🔓 Açık Erişim
Özet
Objective: In order to detect the damage caused by obesity and hyperlipidemia to the cardiovascular system in the early period, parameters that will be used for follow up of these diseases and provide information about the changes are needed. It is of course valuable to measure multiple parameters simultaneously with fast, high efficiency and less sample quantity in the measurement of these parameters. Material and Methods: We have studied serum levels of cardiovascular risk parameters sE-Selectin, follistatin, PAPP-A, sPECAM-1, pentraxin-3 and tissue factor using the multiplex immunoassay method in women primary hyperlipidemic and obese hyperlipidemic. In addition, lipid profile, liver enzymes and blood glucose were measured by routine methods. We have studied these parameters in serum of 30 healthy women, 28 primary hyperlipidemic and 32 obese hyperlipidemic women. Results: sE-selectin (p<0.01) levels were significantly higher than control group. Serum follistatin levels were significantly higher in obese hyperlipidemic group (p<0.001) in obese hyperlipidemic group and primary hyperlipidemic group (p<0.01) compared to control group. Moreover serum sPECAM-1 (p<0.001) levels were significantly higher in obese hyperlipidemic group and primary hyperlipidemic group compared to control group. There were no significant differences between serum PAPP-A, pentraxin-3 and tissue factor levels of the groups. Conclusion:Our findings suggest that hyperlipidemia associated with obesity may be the cause of cardiovascular disease rather than hyperlipidemia.
Yazarlar (4)
1
Betül Bacak
ORCID: 0000-0001-6748-7763
2
Fatma Humeyra Yerlikaya
3
Ümmügülsüm Can
4
Murat Baş
ORCID: 0000-0002-4523-9600
Anahtar Kelimeler
Follistatin
PAPP-A
Pentraxin-3
SE-Selectin
SPECAM-1
Tissue factor
Kurumlar
Konya Education and Research Hospital
Konya Turkey
Necmettin Erbakan Üniversitesi
Meram Turkey
Metrikler
1
Atıf
4
Yazar
6
Anahtar Kelime