Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Serum Endocan Level and Its Correlation with Clinicopathologic Features in Patients with Papillary Thyroid Cancer
Turkish Journal of Endocrinology and Metabolism · Aralık 2021
YÖKSİS Kayıtları
Serum Endocan Level and Its Correlation with Clinicopathologic Features in Patients with Papillary Thyroid Cancer
The Turkish Journal of Endocrinology and Metabolism · 2022 ESCI
PROFESÖR FATMA HÜMEYRA YERLİKAYA AYDEMİR →
Serum Endocan Level and Its Correlation with Clinicopathologic Features in Patients with Papillary Thyroid Cancer
The Turkish Journal of Endocrinology and Metabolism · 2022 Scopus
PROFESÖR FATMA HÜMEYRA YERLİKAYA AYDEMİR →
Makale Bilgileri
DergiTurkish Journal of Endocrinology and Metabolism
Yayın TarihiAralık 2021
Scopus ID2-s2.0-85122975566
Erişim🔓 Açık Erişim
Özet
Objective: Endocan, also known as endothelial cell specific molecule-1, is a vascular endothelium-derived factor and plays a key role in angiogenesis. The aim of this study is to assess serum endocan level in papillary thyroid cancer (PTC) patients which has not been investigated before. Material and Methods: This study included 48 patients with PTC who underwent total thyroidectomy between November 2018 and May 2019. As the control group, 40 age- and sexmatched cases with benign thyroid nodules were included. Serum samples were obtained from the patients before surgery. Serum endocan levels of the patients and controls were measured and the results were compared. The relationship between endocan levels and clinicopathological factors was investigated. Cases with benign thyroid nodules were included as the control group. Results: PTC patients had higher mean serum endocan level than control subjects (45.1±9.6 vs. 37.7±8.3 pg/mL, p<0.001). In PTC patients, there was no relationship between serum endocan levels and histopathologic variant, lymphatic or vascular invasion, surrounding thyroid tissue invasion, lymph node metastasis, surgical margin status, tumor-node-metastasis stage and American Thyroid Association risk stratification group, age and tumor size. Conclusion: This study suggests that, if supported by more comprehensive studies with a sufficiently large sample size in the future, serum endocan level may be used as an adjunctive test in the diagnosis of PTC in patients with thyroid nodules.
Yazarlar (10)
1
Musa Kürşad Şener
ORCID: 0000-0002-5092-3108
2
Melia Karaköse
ORCID: 0000-0001-7990-8350
3
Muhammet Kocabas
ORCID: 0000-0002-6473-4164
4
Taha Ulutan Kars
ORCID: 0000-0003-4013-4647
5
Cihad Solak
ORCID: 0000-0002-3784-144X
6
Fethi Yönet
ORCID: 0000-0002-8534-3170
7
Mehmet Emin Gerek
ORCID: 0000-0003-4792-0544
8
Fatma Humeyra Yerlikaya
9
Mustafa Kulaksızoğlu
ORCID: 0000-0001-9908-7449
10
Feridun Karakurt
ORCID: 0000-0001-7629-9625
Anahtar Kelimeler
Angiogenesis
Endocan
Endothelial-cell-specific molecule-1
Papillary thyroid cancer
Kurumlar
Cihanbeyli State Hospital
Konya Türkiye
Konya Numune State Hospital
Konya Turkey
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Üniversitesi
Selçuklu Turkey