Scopus
YÖKSİS Eşleşti
Assessment of the effects of antihistamine drugs on mood, sleep quality, sleepiness, and dream anxiety
International Journal of Psychiatry in Clinical Practice · Ocak 2014
YÖKSİS Kayıtları
Assessment of the effects of antihistamine drugs on mood, sleep quality, sleepiness, and dream anxiety
International Journal of Psychiatry in Clinical Practice · 2014 SSCI
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Makale Bilgileri
DergiInternational Journal of Psychiatry in Clinical Practice
Yayın TarihiOcak 2014
Cilt / Sayfa18 · 161-168
Scopus ID2-s2.0-84906256899
Özet
Objective. There are limited comparative studies on classic and new-generation antihistamines that affect sleep quality and mood. The purpose of this study was to determine and compare the effects of classic and new-generation antihistamines on sleep quality, daytime sleepiness, dream anxiety, and mood. Methods. Ninety-two patients with chronic pruritus completed study in the dermatology outpatient clinic. Treatments with regular recommended therapeutic doses were administered. The effects of antihistaminic drugs on mood, daytime sleepiness, dream anxiety, and sleep quality were assessed on the first day and 1 month after. Results. Outpatients who received cetirizine and hydroxyzine treatments reported higher scores on the depression, anxiety, and fatigue sub-scales than those who received desloratadine, levocetirizine, and rupatadine. Pheniramine and rupatadine were found to be associated with daytime sleepiness and better sleep quality. UKU side effects scale scores were significantly elevated among outpatients receiving pheniramine. Classic antihistamines increased daytime sleepiness and decreased the sleep quality scores. New-generation antihistamines reduced sleep latency and dream anxiety, and increased daytime sleepiness and sleep quality. Conclusion. Both antihistamines, significantly increased daytime sleepiness and nocturnal sleep quality. Daytime sleepiness was significantly predicted by rupadatine and pheniramine treatment. Cetirizine and hydroxyzine, seem to have negative influences on mood states. Given the extensive use of antihistamines in clinical settings, these results should be more elaborately examined in further studies. © 2014 Informa Healthcare.
Yazarlar (7)
1
Pinar Guzel Ozdemir
2
Ayşe Serap Karadag
3
Yavuz Selvi
4
Murat Boysan
ORCID: 0000-0001-6244-8378
5
Serap Gunes Bilgili
6
Adem Aydin
7
Sevda Onder
Anahtar Kelimeler
Antihistamines
Daytime sleepiness
Dream anxiety
Mood
Sleep quality
Kurumlar
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Üniversitesi
Selçuklu Turkey
T.C. Saglik Bakanligi Istanbul Goztepe Egitim ve Arastirma Hastanesi
Goztepe Turkey
Van Yüzüncü Yıl Üniversitesi
Van Turkey
Metrikler
47
Atıf
7
Yazar
5
Anahtar Kelime