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Can nasal decongestants trigger a manic episode?

Dusunen Adam - The Journal of Psychiatry and Neurological Sciences · Ocak 2020

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YÖKSİS Kayıtları
Can nasal decongestants trigger a manic episode?
Dusunen Adam The Journal of Psychiatry and Neurological Sciences · 2020 TR DİZİN
DOÇENT ALİ KANDEĞER →
Can nasal decongestants trigger a manic episode?
Dusunen Adam The Journal of Psychiatry and Neurological Sciences · 2020 TR DİZİN
PROFESÖR YAVUZ SELVİ →
Can nasal decongestants trigger a manic episode?
Dusunen Adam The Journal of Psychiatry and Neurological Sciences · 2020 Scopus
DOKTOR ÖĞRETİM ÜYESİ RUKİYE TEKDEMİR →

Makale Bilgileri

DergiDusunen Adam - The Journal of Psychiatry and Neurological Sciences
Yayın TarihiOcak 2020
Cilt / Sayfa33 · 96-98
Erişim🔓 Açık Erişim
Özet Among the sympathomimetic drugs, phenylephrine, pseudoephedrine, and ephedrine are the ones that have been used most commonly in oral medication for the relief of nasal congestion. There are reports suggesting that psychiatric cases have been triggered by central nervous system stimulant drugs used as nasal decongestants. In this report, we would like to present a male patient with bipolar disorder undergoing two manic episodes, both triggered by cold medicine. A 25-year-old male patient was seen in the psychiatric outpatient clinic with increasing complaints such as raised level of energy, talkativeness, decreasing sleep, increasing libido, and visual and auditory hallucinations after using an cold medicine containing phenylephrine. Also, 2 years ago, he had a manic attack triggered after the use of cold medication. The patient's manic symptoms were stabilized with lithium 900 mg/day and olanzapine 15 mg/day and his functionality improved. According to his history, the psychometric tests, psychiatric evaluation, and the 6 months follow-up, he was diagnosed with "substance/ medication-induced bipolar and related disorder" according to DSM-5 diagnostic criteria. He had not suffered any mood or psychosis episodes before the use of nasal decongestants, no family history of bipolar disorder, a 16-month period of wellbeing without using a mood stabilizer between 2 episodes, and remission after 1-month anti-manic treatment after the cessation of the cold medicine, supporting the view that the adrenergic drugs with a central stimulant effect may have triggered the manic episodes.

Yazarlar (4)

1
Ali Kandeger
ORCID: 0000-0001-6940-0940
2
Rukiye Tekdemir
ORCID: 0000-0001-7912-5727
3
Barış Şen
ORCID: 0000-0002-3902-1816
4
Yavuz Selvi

Anahtar Kelimeler

Ephedrine Manic episode Phenylephrine Pseudoephedrine Substance/medication-induced bipolar and related disorder

Kurumlar

Selçuk Tip Fakültesi
Konya Turkey

Metrikler

2
Atıf
4
Yazar
5
Anahtar Kelime

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