Scopus
YÖKSİS DOI Eşleşti
SJR Q1
A half-natural origin approach for anticancer and antioxidant activities using sporopollenin and pillar[5]arene macroring
International Journal of Biological Macromolecules · Nisan 2025
YÖKSİS Kayıtları
A half-natural origin approach for anticancer and antioxidant activities using sporopollenin and pillar[5]arene macroring
International Journal of Biological Macromolecules · 2025 SCI-Expanded
Prof. Dr. AHMED NURİ KURŞUNLU →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Immobilization and characterization of hemoglobin on modified sporopollenin surfaces
2012 ISSN: 0141-8130 SCI 2 atıf
Prof. Dr. MUSTAFA ÖZMEN →
Binding of actin to thioglycolic acid modified superparamagnetic nanoparticles for antibody conjugation
2015 ISSN: 01418130 SCI-Expanded
Prof. Dr. ESRA MALTAŞ ÇAĞIL →
Immobilization and characterization of hemoglobin on modified sporopollenin surfaces
2012 ISSN: 01418130 SCI-Expanded 1 atıf
Prof. Dr. ESRA MALTAŞ ÇAĞIL →
Magnetic nanoparticles serum proteins bioconjugates for binding of irinotecan
2015 ISSN: 01418130 SCI-Expanded
Prof. Dr. SALİH ZEKİ BAŞ →
Immobilization of Candida rugosa lipase on sporopollenin from Lycopodium clavatum
2009 ISSN: 0141-8130 SCI-Expanded
Prof. Dr. ELİF ÖZYILMAZ →
Magnetic nanoparticles serum proteins bioconjugates for binding of irinotecan
2015 ISSN: 01418130 SCI-Expanded
Prof. Dr. ESRA MALTAŞ ÇAĞIL →
Synthesis and characterization of novel nano chitosan Schiff base and use of lead II sensor
2012 ISSN: 01418130 SCI-Expanded 7 atıf
Prof. Dr. SEMAHAT KÜÇÜKKOLBAŞI →
Chitosan sporopollenin microcapsules Preparation characterisation and application in heavy metal removal
2015 ISSN: 01418130 SCI-Expanded
Prof. Dr. GÜLŞİN ARSLAN →
Immobilization and characterization of hemoglobin on modified sporopollenin surfaces
2012 ISSN: 01418130 SCI-Expanded 1 atıf
Prof. Dr. İLKAY HİLAL GÜBBÜK →
Magnetic nanoparticles serum proteins bioconjugates for binding of irinotecan
2015 ISSN: 01418130 SCI-Expanded 2 atıf
Prof. Dr. MUSTAFA ÖZMEN →
Characteristics of corneal lens chitin in dragonfly compound eyes
2016 ISSN: 01418130 SCI
Prof. Dr. GÜLŞİN ARSLAN →
Evaluation of antibacterial properties on polysulfone composite membranes using synthesized biogenic silver nanoparticles with Ulva compressa (L.) Kütz. and Cladophora glomerata (L.) Kütz. extracts
2018 ISSN: 01418130 SSCI
Prof. Dr. MUSTAFA ERSÖZ →
Supplementing capsaicin with chitosan-based films enhanced the anti-quorum sensing, antimicrobial, antioxidant, transparency, elasticity and hydrophobicity
2018 ISSN: 0141-8130 SCI
Prof. Dr. İDRİS SARGIN →
Characteristics of corneal lens chitin in dragonfly compound eyes
2016 ISSN: 01418130 SCI
Prof. Dr. İDRİS SARGIN →
Chitin extraction and characterization from Daphnia magna resting eggs
2013 ISSN: 0141-8130 SCI
Prof. Dr. İDRİS SARGIN →
Chitosan nanofiber production from Drosophila by electrospinning
2016 ISSN: 01418130 SCI
Prof. Dr. İDRİS SARGIN →
Chitosan/sporopollenin microcapsules: Preparation, characterisation and application in heavy metal removal
2015 ISSN: 01418130 SCI
Prof. Dr. İDRİS SARGIN →
Controlled release and anti-proliferative effect of imatinib mesylate loaded sporopollenin microcapsules extracted from pollens of Betula pendula
2017 ISSN: 01418130 SCI
Prof. Dr. İDRİS SARGIN →
Detailed adsorption mechanism of plasmid DNA by newly isolated cellulose from waste flower spikes of Thypa latifolia using quantum chemical calculations
2017 ISSN: 01418130 SCI
Prof. Dr. İDRİS SARGIN →
Effect of different animal fat and plant oil additives on physicochemical, mechanical, antimicrobial and antioxidant properties of chitosan films
2018 ISSN: 0141-8130 SCI
Prof. Dr. İDRİS SARGIN →
Makale Bilgileri
ISSN01418130
Yayın TarihiNisan 2025
Cilt / Sayfa303
Scopus ID2-s2.0-85216812356
Özet
Sporopollenin is a natural biomacromolecule which can be found in the outer wall (exine) of spores or pollens that it can be performed with clever designing in a lot of innovative and scientific areas. In this paper, a novel sporopollenin reformed with a recently synthesized pillar[5]arene molecule were elucidated by FT-IR spectroscopy, TGA and SEM techniques. This study is the first report leading to a comprehensive investigation of the biological applications of a functionalized bio-microcapsule including antioxidant and anticancer properties. Two in vitro assays (DPPH and FRAP) were used to determine the antioxidant activities of sporopollenin and functionalized microcapsules. Furthermore, the anticancer activities of these microcapsules were tested on 2 different cancer cell lines (HT-29 and MCF-7), and a fibroblast cell line (L929) by the Alamar blue assay. Among the samples tested in the antioxidant capacity results, especially Sp-P[5] exhibited higher antioxidant capacity and stood out with IC50: 101.98 ± 4.32 μg/mL in DPPH assay and IC50: 87.97 ± 3.14 μg/mL in FRAP assay. Similar to the antioxidant result, Sp-P[5] bio-microcapsule had greater cell inhibition on HT-29 (IC50: 132.31 ± 5.38 μg/mL), MCF-7 (IC50: 107.30 ± 8.28 μg/mL), and L929 (IC50: 255.80 ± 4.91 μg/mL) cell lines than Sp and Sp-APTMS. The analysis results in the study show promise for the development of sporopollenin-based microcapsules to deliver and enhance the biological activity of compounds with therapeutic potential.
Yazarlar (3)
1
Funda Ulusu
2
Ali Bilgiç
3
Ahmed Nuri Kursunlu
Anahtar Kelimeler
Anti-cancer
Antioxidant
Microcapsule
Pillar[5]arene
Sporopollenin
Kurumlar
Karamanoğlu Mehmetbey Üniversitesi
Karaman Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
International Journal of Biological Macromolecules
Q1
SJR Skoru1,287
H-Index247
YayıncıElsevier B.V.
ÜlkeNetherlands
Biochemistry (Q1)
Biomaterials (Q1)
Food Science (Q1)
Structural Biology (Q1)
Molecular Biology (Q2)
Metrikler
6
Atıf
3
Yazar
5
Anahtar Kelime