Scopus
YÖKSİS DOI Eşleşti
SJR Q1
Optimization of ultrasound-assisted extraction from Olea europaea leaves and analysis of their antioxidant and enzyme inhibition activities
Food Bioscience · Ocak 2025
YÖKSİS Kayıtları
Optimization of ultrasound-assisted extraction from Olea europaea leaves and analysis of their antioxidant and enzyme inhibition activities
Food Bioscience · 2025 SCI
Prof. Dr. GÖKHAN ZENGİN →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Functional constituents of six wild edible Silene species: A focus on their phytochemical profiles and bioactive properties
2018 ISSN: 2212-4292 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
Functional constituents of six wild edible Silene species: A focus on their phytochemical profiles and bioactive properties
2018 ISSN: 2212-4292 SCI
Prof. Dr. GÖKHAN ZENGİN →
Pigmented whole maize grains for functional value added and low glycemic index snack production
2021 ISSN: 2212-4292 SCI-Expanded Q1
Prof. Dr. SULTAN ARSLAN TONTUL →
Pigmented Whole Maize Grains for Functional Value Added and Low Glycemic Index Snack Production
2021 ISSN: 2212-4292 SCI-Expanded Q1
Doç. Dr. HÜMEYRA ÇETİN BABAOĞLU →
Anticancer and biological properties of leaf and flower extracts of Echinacea purpurea (L.) Moench
2021 ISSN: 2212-4292 SCI-Expanded Q2
Prof. Dr. GÖKHAN ZENGİN →
Modulating of food glycemic response by lactic acid bacteria
2022 ISSN: 2212-4292 SCI-Expanded Q1
Prof. Dr. SULTAN ARSLAN TONTUL →
Integration of in vitro and in silico approaches to assess three Astragalus species from Turkey flora: A novel spotlight from lab bench to functional applications
2022 ISSN: 2212-4292 SCI-Expanded Q2
Prof. Dr. EVREN YILDIZTUGAY →
Evaluating the phyto-complexity and poly-pharmacology of spices: The case of Aframomum melegueta K. Schum (Zingiberaceae)
2022 ISSN: 2212-4292 SCI-Expanded Q1
Prof. Dr. GÖKHAN ZENGİN →
Effect of oat bran addition on the survival of selected probiotic strains in Turkish fermented sausage during cold storage
2023 ISSN: 2212-4292 SCI-Expanded Q2
Prof. Dr. CEMALETTİN SARIÇOBAN →
Revealing the proteolytic characteristics of lactobacillus, lacticaseibacillus, and lactiplantibacillus isolates by in vitro and in situ perspectives
2023 ISSN: 2212-4292 SCI-Expanded Q1
Doç. Dr. TALHA DEMİRCİ →
Storage stability, heat stability, controlled release and antifungal activity of liposomes as alternative fungal preservation agents
2023 ISSN: 2212-4292 SCI-Expanded Q1
Dr. Öğr. Üyesi MİNE ASLAN →
Unlocking the functional potential of Nitraria schoberi extracts using chemical fingerprinting, biological efficiencies, in silico and network pharmacological approaches
2024 ISSN: 2212-4292 SCI-Expanded Q1
Prof. Dr. EVREN YILDIZTUGAY →
Harnessing the chemical composition and anti-oxidant, anti-enzymatic, and anti-cancer activities of two Corydalis species (C. erdelii and C. solida) by using in vitro and in silico analysis
2024 ISSN: 2212-4292 SCI-Expanded Q1
Prof. Dr. EVREN YILDIZTUGAY →
Effects of ultrasound-assisted marination on spent hen meats: Microstructure, textural and technological properties
2024 ISSN: 2212-4292 SCI Q1
Dr. Öğr. Üyesi HALİME ALP →
From parasitic life to health-promoting applications - a versatile goldmine discovered in natures secret treasure chest: Orobanche nana
2024 ISSN: 2212-4292 SCI-Expanded Q1
Prof. Dr. EVREN YILDIZTUGAY →
Effects of ultrasound-assisted marination on spent hen meats: Microstructure, textural and technological properties
2024 ISSN: 2212-4292 SCI-Expanded Q1
Doç. Dr. KÜBRA ÜNAL →
Exploring the chemical constituents and biological activities of leaf and twig extracts of two Amygdalus species from Turkeys flora: Cell-free, in vitro and molecular docking approaches
2025 ISSN: 2212-4292 SCI-Expanded Q1
Prof. Dr. EVREN YILDIZTUGAY →
Optimization of ultrasound-assisted extraction from Olea europaea leaves and analysis of their antioxidant and enzyme inhibition activities
2025 ISSN: 2212-4292 SCI Q1
Prof. Dr. GÖKHAN ZENGİN →
Chemical characterization and biological properties of oyster and shiitake mushrooms extracts and their liposomal formulations
2024 ISSN: 2212-4292 SCI-Expanded Q1
Prof. Dr. GÖKHAN ZENGİN →
Metabolomics-guided discrimination of constituents in five commercial apple (Malus × domestica Borkh.) cultivars: Assessment of their antioxidant, neuroprotective, and antidiabetic activities for potential use as functional food
2024 ISSN: 2212-4292 SCI-Expanded Q1
Prof. Dr. GÖKHAN ZENGİN →
Makale Bilgileri
Dergi
Food Bioscience
ISSN22124292
Yayın TarihiOcak 2025
Cilt / Sayfa63
Scopus ID2-s2.0-85214290820
Özet
Olive leaves (Olea europaea L.) are rich source of bioactive compounds but are usually declared as bio-waste. Knowledge from traditional medicine, supported by modern research, has shown the high value of this bio-waste, and the great benefits of its use. The first step in exploiting the biological potential of olive leaves is the rationalization of the extraction process, through which extracts with high biological and market value could be obtained. This study aimed to investigate the influence of different extraction parameters, including solvent concentration, time, temperature, and ratio, on total phenolics, total flavonoids, antioxidant and enzyme-inhibiton activities. The optimal extraction conditions were determined using an Artificial Neural Network (ANN) model. The results revealed that the optimal conditions for the extraction of total bioactive compounds and antioxidant activities from olive leaves were obtained using ethanol concentration of 90%, extraction time 15 min, temperature of 45 °C, and plant:ethanol ratio 1:30. Under these conditions, the extract exhibited high levels of total phenolic content (TPC: 89.05 ± 3.9 mg GAE/g), total flavonoid content (TFC: 19.98 ± 0.38 mg RE/g), and potent antioxidant activity (DPPH: 195.12 ± 6.85 mg TE/g, ABTS: 270.73 ± 1.00 mg TE/g, CUPRAC: 66.14 ± 25.27 mg TE/g, FRAP: 233.58 ± 21.33 mg TE/g). Additionally, the extract demonstrated significant inhibitory effects on α-amylase (0.35 ± 0.00 mmol ACE/g) and tyrosinase (49.23 ± 1.22 mg KAE/g) enzymes. Taken together, the presented results may be valuable for the preparation of health-promoting formulations using olive leaves in the pharmaceutical and cosmeceutical industries.
Yazarlar (4)
1
Sengul Uysal
2
Biljana Lončar
3
Aleksandra Cvetanović Kljakić
4
Gokhan Zengin
ORCID: 0000-0001-6548-7823
Anahtar Kelimeler
Antioxidant
Artificial neural network (ANN)
Enyzme inhibiton
Olive leaves
Optimization
Kurumlar
Erciyes Üniversitesi
Kayseri Turkey
Selçuk Üniversitesi
Selçuklu Turkey
University of Novi Sad
Novi Sad Serbia
Scimago Dergi (ISSN Eşleşmesi)
Food Bioscience
Q1
SJR Skoru1,119
H-Index94
YayıncıElsevier Ltd
ÜlkeUnited Kingdom
Biochemistry (Q1)
Food Science (Q1)
Metrikler
5
Atıf
4
Yazar
5
Anahtar Kelime