Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Determination of Mannheimia haemolytica and its macrolide antibiotic resistance genes in fibrinous pneumonia of cattle
Revista Cientifica de la Facultad de Veterinaria · Ocak 2024
YÖKSİS Kayıtları
Determination of Mannheimia haemolytica and its macrolide antibiotic resistance genes in fibrinous pneumonia of cattle
REVISTA CIENTIFICA-FACULTAD DE CIENCIAS VETERINARIAS · 2024 SCI-Expanded
DOÇENT ASLI BALEVİ →
Determination of Mannheimia haemolytica and its macrolide antibiotic resistance genes in fibrinous pneumonia of cattle
Revista Científica · 2024 Science Citation Index Expanded (SciSearch®) Journal Citation Reports/Science Edition SCOPUS Zoological Record Biological Abstracts BIOSIS Previews CAB Abstracts (Index Veterinarius, Veterinary Bulletin) FISHLIT
DOÇENT MEHMET BURAK ATEŞ →
Determination of Mannheimia haemolytica and its macrolide antibiotic resistance genes in fibrinous pneumonia of cattle
Revista Científica · 2024 SCI-Expanded
PROFESÖR ÖZGÜR ÖZDEMİR →
Determination of Mannheimia haemolytica and its macrolide antibiotic resistance genes in fibrinous pneumonia of cattle
Revista Científica · 2024 Science Citation Index Expanded (SciSearch®) Journal Citation Reports/Science Edition SCOPUS Zoological Record Biological Abstracts BIOSIS Previews CAB Abstracts (Index Veterinarius, Veterinary Bulletin) FISHLIT
PROFESÖR FATİH HATİPOĞLU →
Makale Bilgileri
DergiRevista Cientifica de la Facultad de Veterinaria
Yayın TarihiOcak 2024
Cilt / Sayfa34
Scopus ID2-s2.0-85217562262
Erişim🔓 Açık Erişim
Özet
Early diagnosis and timely initiation of effective treatment are critical for the pneumonic pasteurellosis, which is mostly caused by Mannheimia haemolytica. But recently, strains of M. haemolytica resistant to antibiotics have begun to emerge, making the treatment of infections more difficult. Therefore, it is important to investigate the erm (42), msr (E) and mph (E) genes, which are held responsible for the resistance to antibiotics.The purpose of the present study was aimed to diagnose the presence of M. haemolytica by IHC method from lung tissue samples of young and adult cattle, and calves, also to detect erm (42), msr (E) and mph (E) genes, which are mostly detected in Pasteurella multocida but recently detected in M. haemolytica, by PCR method. In present study, paraffin blocks obtained from 100 young and adult cattle, and calves lung samples, and whose treatment was not responded, were used. Accordingly, the presence of M. haemolytica was detected by IHC in a total 52 cases of in 21 (38%) of the calves, 22 (69%) of the young cattle, and 9 (69%) of the adult cattle. At least one macrolide resistance gene was found by real–time PCR method in 75% of these positive cases. It was thought that the percentage frequency of these genes, which cause resistance by increasing the minimum inhibitory concentrations of macrolide group antibiotics used in the treatment, by high amounts, makes the treatment of infections difficult and causes serious economic losses by causing errors in effective antibiotic selection. Recently, strains of M. haemolytica resistant to antibiotics have begun to emerge, making the treatment of infections more difficult. For this reason, it is recommended that this type of prevalence studies should be renewed periodically due to possible resistance development and the repeated use of antibiotics with resistive shape should be avoided.
Yazarlar (6)
1
Fatih Hatipoglu
2
Funda Terzi
ORCID: 0000-0002-6184-5408
3
Mehmet Burak Ates
ORCID: 0000-0003-1297-426X
4
Aslı Balevı
5
O. Ozdemir
6
M. Ortatatli
Anahtar Kelimeler
antibiotic resistance
cattle
erm (42)
fibrinous pneumonia
macrolide
Mannheimia haemolytica
mph (E)
msr (E)
Kurumlar
Kastamonu University
Kastamonu Turkey
Kyrgyz-Turkish Manas University
Bishkek Kyrgyzstan
Selçuk Üniversitesi
Selçuklu Turkey