Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q3
In-vitro antiviral activity of Neem (Azadirachta indica L.) Bark extract against BCoV, BHV-1, BPIV-3, and BEVs
Veterinarski Arhiv · Ocak 2025
YÖKSİS Kayıtları
In-vitro antiviral activity of Neem (Azadirachta indica L.) Bark extract against
BCoV, BHV-1, BPIV-3, and BEVs
VETERINARSKI ARHIV · 2025 SCI-Expanded
Arş. Gör. HATİCE PELİN ASLIM →
YÖKSİS Kayıtları — ISSN Eşleşmesi
The Vomeronasal Organ in Angora Goats Capra Hircus
2001 ISSN: 0372-5480 SCI-Expanded
Prof. Dr. EMRULLAH EKEN →
The Effects of Aflatoxin and Glucomannan on Coagulation Parameters in Rabbits
2009 ISSN: 0372-5480 SCI-Expanded 3 atıf
Prof. Dr. NURCAN DÖNMEZ →
The evaluation of endometrial cytology in cows with acute and chronic endometritis
2015 ISSN: 0372-5480 SCI-Expanded
Prof. Dr. ERTAN ORUÇ →
Miyocarditis associated with foot and mouth disease in suckling calves
2015 ISSN: 0372-5480 SCI-Expanded
Prof. Dr. ERTAN ORUÇ →
Comparison of two different primer sets for detection of Pasteurellacaballi in bronchoalveolar lavage fl uids samples from thoroughbred Arabian foals using PCR
2016 ISSN: 0372-5480 SCI-Expanded
Prof. Dr. HASAN HÜSEYİN HADİMLİ →
The relationship of copper concentrations in feed and plasma to developmental orthopedic disease in foals
2016 ISSN: 0372-5480 SCI-Expanded
Prof. Dr. ÖZGÜR ÖZDEMİR →
Comparison of two different primer sets for detection of Pasteurellacaballi in bronchoalveolar lavage fluids samples from thoroughbredArabian foals using PCR
2016 ISSN: 0372-5480 SCI-Expanded
Doç. Dr. ASLI BALEVİ →
Comparison of two different primer sets for detection of Pasteurellacaballi in bronchoalveolar lavage fl uids samples from thoroughbredArabian foals using PCR
2016 ISSN: 0372-5480 SCI-Expanded
Prof. Dr. MEHMET MADEN →
The Vomeronasal Organ In Angora Goats Capra Hircus
2001 ISSN: 0372-5480 SCI-Expanded
Prof. Dr. KAMİL BEŞOLUK →
The Vomeronasal Organ in Angora Goats (Capra hircus)
2001 ISSN: 0372-5480 SCI
Prof. Dr. KAMİL BEŞOLUK →
Histological and histomorphometric studies on the cerebellar cortex and silver stained nucleolus organizer regions of Purkinje neurons in chronic morphine-treated rats
2018 ISSN: 0372-5480 SCI
Prof. Dr. İLHAMİ ÇELİK →
The impact of ambroxol on the anti-inflammatory effect of azithromycin in
lung tissue
2021 ISSN: 0372-5480 pub med
Prof. Dr. AYŞE ER →
The effect of intra-articular platelet-rich plasma, bio-physically activated
PRP and mesenchymal stem cell administration for interleukins in dogs
with osteoarthritis
2022 ISSN: 0372-5480 SCI-Expanded Q3
Doç. Dr. KURTULUŞ PARLAK →
The effect of intra-articular platelet-rich plasma, bio-physically activated PRP and mesenchymal stem cell administration for interleukins in dogs with osteoarthritis
2022 ISSN: 0372-5480 SCI-Expanded Q4
Prof. Dr. KAMİL ÜNEY →
The protective effects of Nigella sativa, thymoquinone and bentonite in experimental aflatoxicosis model in broilers
2023 ISSN: 0372-5480 SCI-Expanded Q4
Doç. Dr. MEHMET BURAK ATEŞ →
Investigation of the tumor microenvironment, hypoxia and angiogenesis by immunohistochemical and histopathological methods in canine mammary tumors
2023 ISSN: 0372-5480 Science Citation Index Expanded (SciSearch®) Journal Citation Reports/Science Edition SCOPUS Zoological Record Biological Abstracts BIOSIS Previews CAB Abstracts (Index Veterinarius, Veterinary Bulletin) FISHLIT
Prof. Dr. FATİH HATİPOĞLU →
The protective effects of Nigella sativa, thymoquinone and bentonite in experimental aflatoxicosis model in broilers
2023 ISSN: 0372-5480 CABI, EBSCO, Scobus
Prof. Dr. MUSTAFA ORTATATLI →
The protective effects of Nigella sativa, thymoquinone and bentonite
in experimental aflatoxicosis model in broilers
2023 ISSN: 0372-5480 SCI-Expanded Q4
Prof. Dr. HALİS UĞUZ →
In-vitro antiviral activity of Neem (Azadirachta indica L.) Bark extract against
BCoV, BHV-1, BPIV-3, and BEVs
2025 ISSN: 0372-5480 SCI-Expanded
Arş. Gör. HATİCE PELİN ASLIM →
High point seroprevalence of Toxoplasma gondii and Neospora caninum in sheep with abortion history in the central part of Türkiye
2025 ISSN: 0372-5480 SCI-Expanded
Doç. Dr. ONUR CEYLAN →
Makale Bilgileri
Dergi
Veterinarski Arhiv
ISSN03725480
Yayın TarihiOcak 2025
Cilt / Sayfa95 · 75-88
Scopus ID2-s2.0-85215321889
Erişim🔓 Açık Erişim
Özet
Neem extracts and bioactive compounds which have been widely utilized in medicine for some time, exhibit regulatory effects in relation to various biological mechanisms, and include antioxidant, anti-inflammatory, antihyperglycemic, as well as antifungal, antibacterial, and antiviral properties. Thus, this clearly underscores the pivotal role of Neem Bark in modulation of various biological pathways. The present study evaluated the antiviral activity of Azadirachta indica (Neem Bark) extract on Bovine Corona Virus (BCoV), Bovine Herpes Virus-1 (BHV-1), Bovine Parainfluenza Virus-3 (BPIV-3) and Bovine Entero Virus (BEV) in vitro. The aim of the present study was to determine whether its antiviral activities were effective in the cell entry or replication phase of each virus. As a result of the WST-1 test, performed to determine the non-cytotoxic dose of NBE, it was determined that concentrations lower than 0.87 mg/mL were not cytotoxic in an MDBK cell line. Although Neem Bark extract (NBE) did not have any significant effect on the attachment of Bovine Parainfluenza Virus-3 and Bovine Entero Virus to the host cell, a 100-fold decrease in TCID50 (50% tissue culture infectious dose) values of Bovine Corona Virus treated with Neem extract was detected, and virus replication was completely blocked in Bovine Herpes Virus-1. In conclusion, we suggest that it would be valuable to evaluate its antiviral activity on Bovine Corona Virus and Bovine Herpes Virus-1 in vivo. Additionally, the detailed determination of the effectiveness of NBE against other viruses would contribute to future antiviral drug trials.
Yazarlar (3)
1
Hatice Pelin Aslim
2
Hasan Sercan Palanci
3
Oya Bulut
Anahtar Kelimeler
Bovine Corona Virus
Bovine Entero Virus
Bovine Herpes Virus-1
Bovine Parainfluenza Virus-3
Neem Bark
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Veterinarski Arhiv
Q3
OA
SJR Skoru0,208
H-Index38
YayıncıUniversity of Zagreb, Facultty of Veterinary Medicine
ÜlkeCroatia
Veterinary (miscellaneous) (Q3)
Metrikler
2
Atıf
3
Yazar
5
Anahtar Kelime