Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q2
The effects of dexamethasone and minocycline alone and combined with N-acetylcysteine and vitamin E on serum matrix metalloproteinase-9 and coenzyme Q10 levels in aflatoxin B1 administered rats
Polish Journal of Veterinary Sciences · Ocak 2022
YÖKSİS Kayıtları
The effects of dexamethasone and minocycline alone and combined with N-acetylcysteine and vitamin E on serum matrix metalloproteinase-9 and coenzyme Q10 levels in aflatoxin B1 administered rats
Polish Journal of Veterinary Sciences · 2022 SCI-Expanded
Prof. Dr. KAMİL ÜNEY →
The effects of dexamethasone and minocycline alone and combined with N-acetylcysteine and vitamin E on serum matrix metalloproteinase-9 and coenzyme Q10 levels in aflatoxin B1 administered rats
POLISH JOURNAL OF VETERINARY SCIENCES · 2022 SCI
Prof. Dr. BÜNYAMİN TRAŞ →
The effects of dexamethasone and minocycline alone and combined with N-acetylcysteine and vitamin E on serum matrix metalloproteinase-9 and coenzyme Q10 levels in aflatoxin B1 administered rats
POLISH JOURNAL OF VETERINARY SCIENCES · 2022 SCI-Expanded
Prof. Dr. BURAK DİK →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Effect of combinations of intravenous small-volume hypertonic sodium chloride, acetate Ringer, sodium bicarbonate, and lactate Ringer solutions along with oral fluid on the treatment of calf diarrhea
2018 ISSN: 1505-1773 SCI-Expanded Q3
Doç. Dr. AMİR NASERİ →
Effect of combinations of intravenous small-volume hypertonic sodium chloride, acetate Ringer, sodium bicarbonate, and lactate Ringer solutions along with oral fluid on the treatment of calf diarrhea
2018 ISSN: 1505-1773 SCI
Prof. Dr. HASAN GÜZELBEKTEŞ →
The level of serum ionised calcium, aspartate aminotransferase, insulin, glucose, betahydroxybutyrate concentrations and blood gas parameters in cows with left displacement of abomasum
2006 ISSN: 1505-1773 SCI-Expanded
Prof. Dr. MAHMUT OK →
The evaluation of hemostatic dysfunction and disseminated intravascular coagulation in dairy cows with abomasal displacement
2018 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. MUSTAFA ARICAN →
The evaluation of hemostatic dysfunction and disseminated intravascular coagulation in dairy cows with abomasal displacement
2018 ISSN: 1505-1773 SCI-Expanded
Prof. Dr. RAMAZAN ÇÖL →
Glucose-6-phosphate dehydrogenase,glutathione peroxidase, total glutationeand reduced nicotinamide adeninedinucleotide phosphate in milk cellsof subclinical mastitic cows
2018 ISSN: 1505-1773 SCI-Expanded
Prof. Dr. NURİ BAŞPINAR →
Assessment of intestinal and cardiac-related biomarkers in dogs with parvoviral enteritis
2020 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. MAHMUT OK →
Assessment of intestinal and cardiac-related biomarkers in dogs with parvoviral enteritis
2020 ISSN: 1505-1773 SCI-Expanded Q3
Doç. Dr. MERVE İDER →
The clinical efficacy of pentoxifylline and l-glutamine on ischemia and reperfusion injury in cattle with displaced abomasum: a longitudinal study
2021 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. MEHMET MADEN →
The clinical efficacy of pentoxifylline
and l-glutamine on ischemia and reperfusion
injury in cattle with displaced abomasum:
a longitudinal study
2021 ISSN: 1505-1773 SCI-Expanded Q3
Doç. Dr. KURTULUŞ PARLAK →
The clinical efficacy of pentoxifylline and l-glutamine on ischemia and reperfusion injury in cattle with displaced abomasum: a longitudinal study
2021 ISSN: 1505-1773 SCI-Expanded
Prof. Dr. MUSTAFA ARICAN →
The clinical efficacy of pentoxifylline and l-glutamine on ischemia and reperfusion injury in cattle with displaced abomasum: a longitudinal study
2021 ISSN: 1505-1773 SCI-Expanded Q2
Prof. Dr. BÜNYAMİN TRAŞ →
The clinical efficacy of pentoxifylline and l-glutamine on ischemia and reperfusion injury in cattle with displaced abomasum: a longitudinal study
2021 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. RAMAZAN ÇÖL →
The effects of dexamethasone and minocycline alone and combined with N-acetylcysteine and vitamin E on serum matrix metalloproteinase-9 and coenzyme Q10 levels in aflatoxin B1 administered rats
2022 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. KAMİL ÜNEY →
The effects of dexamethasone and minocycline alone and combined with N-acetylcysteine and vitamin E on serum matrix metalloproteinase-9 and coenzyme Q10 levels in aflatoxin B1 administered rats
2022 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. BURAK DİK →
Molecular cloning of the OMP19 gene from Brucella melitensis strain H38 and its antigenicity compared to that of commercial OMP19
2022 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. ZAFER SAYIN →
Molecular cloning of the OMP19 gene from Brucella melitensis strain H38 and its antigenicity compared to that of commercial OMP19
2022 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. OSMAN ERGANİŞ →
The effects of dexamethasone and minocycline alone and combined with N-acetylcysteine and vitamin E on serum matrix metalloproteinase-9 and coenzyme Q10 levels in aflatoxin B1 administered rats
2022 ISSN: 15051773 SCI Q3
Prof. Dr. BÜNYAMİN TRAŞ →
Molecular cloning of the OMP19 gene from Brucella melitensis strain H38 and its antigenicity compared to that of commercial OMP19
2022 ISSN: 1505-1773 SCI-Expanded Q3
Doç. Dr. ALİ USLU →
The effect of tilmicosin and diclofenac sodium combination on cardiac biomarkers in sheep
2023 ISSN: 1505-1773 SCI-Expanded Q3
Doç. Dr. MERVE İDER →
Makale Bilgileri
ISSN15051773
Yayın TarihiOcak 2022
Cilt / Sayfa25 · 419-427
Scopus ID2-s2.0-85138610251
Erişim🔓 Açık Erişim
Özet
This study aimed to determine the effects of dexamethasone and minocycline alone and combined treatment with N-acetylcysteine (NAC) and vitamin E on serum coenzyme Q10 (CoQ10) and matrix metalloproteinase-9 (MMP-9) levels in rats administered aflatoxin B1 (AFB1). The study was carried out on 66 male Wistar rats. Following the intraperitoneal (IP) administration of AFB1 at dose of 2 mg/kg, minocycline (45 and 90 mg/kg, IP) and dexamethasone (5 and 20 mg/kg, IP) were administered alone and combined with NAC (200 mg/kg, IP) and vitamin E (600 mg/kg, IP). CoQ10 and MMP-9 levels were analyzed using the HPLC-UV method and a commercial kit by ELISA, respectively. AFB1 increased MMP-9 level and decreased CoQ10 level compared to the control group. After dexamethasone and minocycline administration, there is no increase in CoQ10 level, which is caused by AFB1. However, dexamethasone and minocycline combined with NAC+vitamin E caused significant increases in CoQ10 levels. Dexamethasone and minocycline alone and combined with NAC+vitamin E decreased MMP-9 levels compared to the single AFB1 treated group. The use of MMPs inhibitors and oxidative stress-reducing agents is anticipated to be beneficial in the poisoning with AFB1.
Yazarlar (6)
1
B. Traş
2
H. Eser Faki
3
Zeynep Ozdemir Kutahya
4
Emre Bahcivan
5
Burak Dik
6
Kamil Üney
ORCID: 0000-0002-8674-4873
Anahtar Kelimeler
Aflatoxin B1
coenzyme Q10
matrix metalloproteinase-9
rat
treatment
Kurumlar
Amasya Üniversitesi
Amasya Turkey
Çukurova Üniversitesi
Adana Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Polish Journal of Veterinary Sciences
Q2
SJR Skoru0,348
H-Index39
YayıncıPolska Akademia Nauk
ÜlkePoland
Veterinary (miscellaneous) (Q2)
Medicine (miscellaneous) (Q3)
Metrikler
7
Atıf
6
Yazar
5
Anahtar Kelime