Scopus
YÖKSİS ISSN Eşleşti
SJR Q1
Opposite effects of zinc and melatonin on thyroid hormones in rats
Toxicology · Ocak 2004
YÖKSİS Kayıtları — ISSN Eşleşmesi
Opposite Effects of Zinc and Melatonin on Thyroid Hormones in Rats
2004 ISSN: 0300-483X SCI-Expanded 29 atıf
Prof. Dr. ABDULKERİM KASIM BALTACI →
The Effects of Zinc Deficiency and Supplementation on Lipid Peroxidation in Bone Tissue of Ovariectomized Rats
2004 ISSN: 0300-483X SCI-Expanded 8 atıf
Prof. Dr. ABDULKERİM KASIM BALTACI →
Opposite effects of zinc and melatonin on thyroid hormones in rats.
2004 ISSN: 0300-483X SCI-Expanded
Dr. Öğr. Üyesi AYLİN ÜSTÜN →
Makale Bilgileri
Dergi
Toxicology
ISSN0300483X
Yayın TarihiOcak 2004
Cilt / Sayfa195 · 69-75
Scopus ID2-s2.0-0347416981
Özet
The present study was conducted to investigate how thyroid function in rats is affected by administration of 3mg per kg per day of zinc and/or melatonin. The study was conducted with 40 Sprague-Dawley adult male rats equally divided into four groups: 1 (controls), 2 (zinc-only), 3 (melatonin-only) and 4 (zinc- and melatonin-supplemented). The supplementation was continued for 4 weeks after which the animals were sacrificed and plasma samples were obtained for determination of zinc, melatonin, free- and total triiodothyronine (T3), thyroxine (T4) and thyroid-stimulating hormone (TSH) levels. The free T3, T4 and TSH levels were lower in the melatonin group than in all other groups (P<0.01), while free- and total T3 levels were higher in the zinc group (P<0.01). The group that received zinc and melatonin combined had free thyroid hormone levels higher than the only melatonin group. These results show that melatonin has a thyroid function suppressing action, just the opposite to the actions of zinc. When zinc is administered along with melatonin, its thyroid function suppression is diminished. © 2003 Elsevier Ireland Ltd. All rights reserved.
Yazarlar (5)
1
Abdulkerim Kasim Baltaci
2
Rasim Mogulkoc
3
Aylin Kul
4
Cem Seref Bediz
5
Aysegul Ugur
Anahtar Kelimeler
Melatonin
Rats
Thyroid hormone function
Zinc
Kurumlar
Dokuz Eylül Üniversitesi
Izmir Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Toxicology
Q1
SJR Skoru1,106
H-Index182
YayıncıElsevier Ireland Ltd
ÜlkeIreland
Toxicology (Q1)
Metrikler
80
Atıf
5
Yazar
4
Anahtar Kelime