Scopus
YÖKSİS Eşleşti
A Ratiometric and Switchable Fluorescent Sensor Based on Calix[4]arene-HBT With a Large Stokes Shift for the Real-Time Detecting of Zn<sup>2+</sup>and Cu<sup>2+</sup>in Living Cells
IEEE Sensors Journal · Nisan 2023
YÖKSİS Kayıtları
A Ratiometric and Switchable Fluorescent Sensor Based on Calix[4]arene-HBT With a Large Stokes Shift for the Real-Time Detecting of Zn2+ and Cu2+ in Living Cells
Institute of Electrical and Electronics Engineers (IEEE) · 2023 SCI-Expanded
PROFESÖR SERKAN ERDEMİR →
A Ratiometric and Switchable Fluorescent Sensor Based on Calix[4]arene-HBT With a Large Stokes Shift for the Real-Time Detecting of Zn2+ and Cu2+ in Living Cells
Institute of Electrical and Electronics Engineers (IEEE) · 2023 SCI-Expanded
DOÇENT MEHMET OĞUZ →
Makale Bilgileri
DergiIEEE Sensors Journal
Yayın TarihiNisan 2023
Cilt / Sayfa23 · 6734-6741
Scopus ID2-s2.0-85149411545
Özet
Though Zn2+ and Cu2+ have several critical roles in biological and environmental media, they may also induce a variety of detrimental effects. Hence, the monitoring of trace amounts of Zn2+ and Cu2+ in biological systems and ecological environment is of great significance due to their harmful impacts on living organisms. To serve this purpose, we designed and constructed a simple benzothiazole-calixarene (C-HBT)-based ratiometric and fluorometric probe with a large Stokes shift of 206 nm to recognize Zn2+ and Cu2+. The detection levels of C-HBT for Zn2+/Cu2+ were as low as 35.1 and 66.7 nM, respectively, and high binding constant values were obtained within an extremely short time (10.0 s). Furthermore, with the assistance of inexpensive, viable, and straightforward smartphone and cotton swab applications, C-HBT was successfully applied for the on-site and naked-eye recognition of Zn2+/Cu2+. Finally, the remarkable performance of C-HBT toward Zn2+/Cu2+ with negligible cytotoxicity was achieved in living cells.
Yazarlar (3)
1
Serkan Erdemir
ORCID: 0000-0003-0790-0549
2
Duygu Aydin
3
Mehmet Oguz
Anahtar Kelimeler
Bioimaging
calix[4]arene
copper
ratiometric
zinc
Kurumlar
Karamanoğlu Mehmetbey Üniversitesi
Karaman Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
2
Atıf
3
Yazar
5
Anahtar Kelime