Scopus
YÖKSİS Eşleşti
Lighting up trace carbon monoxide and residual palladium species by a low cytotoxic mitochondria targetable red fluorescent probe: Its large scaled applications
Talanta · Haziran 2023
YÖKSİS Kayıtları
Lighting up trace carbon monoxide and residual palladium species by a low cytotoxic mitochondria targetable red fluorescent probe: Its large scaled applications
TALANTA · 2023 SCI-Expanded
DOÇENT MEHMET OĞUZ →
Lighting up trace carbon monoxide and residual palladium species by a low cytotoxic mitochondria targetable red fluorescent probe: Its large scaled applications
Talanta · 2023 SCI-Expanded
PROFESÖR SERKAN ERDEMİR →
Lighting up trace carbon monoxide and residual palladium species by a low cytotoxic mitochondria targetable red fluorescent probe: Its large scaled applications
Elsevier BV · 2023 SCI-Expanded
PROFESÖR SERKAN ERDEMİR →
Makale Bilgileri
DergiTalanta
Yayın TarihiHaziran 2023
Cilt / Sayfa258
Scopus ID2-s2.0-85150160123
Özet
High levels of residual palladium can lead to serious negative health effects. Carbon monoxide (CO) is a significant gasotransmitter in transporting intermolecular and intramolecular signals to balance several physiological processes. Therefore, there is a need for rapid detection of CO and palladium residue. To address these issues, we have designed a novel light-up fluorescent probe for the detection of Pd and CO. It can not only detect Pd and CO selectively with a remarkable chromogenic and red fluorescent response over other metal ions allowing detection with naked eyes but also discriminate Pd0 and Pd2+/Pd4+ species. The detection reaction is confirmed by HPLC analysis. The probe demonstrates biocompatibility and mitochondrial target ability for potential biological applications. The practical applications based on drug residue and soil analysis, and smartphone have been successfully performed. Bioimaging of the concentration change of Pd and CO in HeLa cells using the probe is successfully applied. Therefore, the present approach can provide early diagnosis of Pd and CO with low detection limit, low cytotoxicity, high selectivity, and sensitivity.
Yazarlar (3)
1
Serkan Erdemir
ORCID: 0000-0003-0790-0549
2
Sait Malkondu
3
Mehmet Oguz
Anahtar Kelimeler
Bioimaging
Carbon monoxide
Fluorescence
Palladium
Red
Kurumlar
Giresun Üniversitesi
Giresun Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
6
Atıf
3
Yazar
5
Anahtar Kelime