Scopus
YÖKSİS Eşleşti
Engineering a “turn-on” NIR fluorescent sensor-based hydroxyphenyl benzothiazole with a cinnamoyl unit for hydrazine and its environmental and in-vitro applications
Environmental Pollution · Şubat 2024
YÖKSİS Kayıtları
Engineering a “turn-on” NIR fluorescent sensor-based hydroxyphenyl benzothiazole with a cinnamoyl unit for hydrazine and its environmental and in-vitro applications
Environmental Pollution · 2024 SCI-Expanded
PROFESÖR SERKAN ERDEMİR →
Engineering a “turn-on” NIR fluorescent sensor-based hydroxyphenyl benzothiazole with a cinnamoyl unit for hydrazine and its environmental and in-vitro applications
Environmental Pollution · 2024 SCI-Expanded
DOÇENT MEHMET OĞUZ →
Makale Bilgileri
DergiEnvironmental Pollution
Yayın TarihiŞubat 2024
Cilt / Sayfa343
Scopus ID2-s2.0-85181587860
Özet
Hydrazine (N2H4), a chemical compound widely used in various industrial applications, causes significant environmental and biological hazards. Therefore, it is crucial to develop methodologies for the visualization and real time tracking of N2H4. In this regard, we have constructed a novel near-infrared fluorescent probe (HBT-Cy) that can effectively detect N2H4 in various samples. HBT-Cy contains 2-(2′-hydroxyphenyl)benzothiazole (HBT), cinnamoyl (Cy), and pyridinium (Py) moieties. Importantly, HBT-Cy exhibits a rapid, selective, and highly sensitive response to N2H4. This response results in the release of HBT-Py and the generation of considerable colorimetric changes along with a significant NIR (near infrared) fluorescence signal, peaking at 685 nm. Advantages of this system include turn on NIR fluorescence with large Stokes shift, (approximately 171 nm), low limit of detection (LOD = 0.11 μM) and quantum yield (0.211). The probe with low cytotoxic behavior demonstrates strong NIR fluorescence imaging capabilities to visualize endogenous and exogenous N2H4 in live cells. This mitochondria-targetable probe shows effective subcellular localization. These results suggest that HBT-Cy is a valuable probe for tracking and investigating the behavior of N2H4 in biological systems and environmental samples.
Yazarlar (3)
1
Mehmet Oguz
2
Serkan Erdemir
ORCID: 0000-0003-0790-0549
3
Sait Malkondu
Anahtar Kelimeler
Endogenous
ESIPT
HBT
Hydrazine
NIR fluorescence
Kurumlar
Giresun Üniversitesi
Giresun Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
2
Atıf
3
Yazar
5
Anahtar Kelime