Scopus
YÖKSİS Eşleşti
Enhancing Effect of Calix[4]arene Amide Derivatives on Lipase Performance in Enantioselective Hydrolysis of Racemic Arylpropionic Acid Methyl Esters
Polycyclic Aromatic Compounds · Ekim 2016
YÖKSİS Kayıtları
Enhancing Effect of Calix 4 arene AmideDerivatives on Lipase Performance inEnantioselective Hydrolysis of RacemicArylpropionic Acid Methyl Esters
POLYCYCLIC AROMATIC COMPOUNDS · 2016 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ NEJDET ŞEN →
Enhancing Effect of Calix 4 arene Amide Derivatives on Lipase Performance in Enantioselective Hydrolysis of Racemic Arylpropionic Acid Methyl Esters
Polycyclic Aromatic Compounds · 2016 SCI-Expanded
PROFESÖR MUSTAFA YILMAZ →
Enhancing Effect of Calix 4 arene Amide Derivatives on Lipase Performance in Enantioselective Hydrolysis of Racemic Arylpropionic Acid Methyl Esters
Polycyclic Aromatic Compounds · 2016 SCI-Expanded
DOÇENT ARZU UYANIK →
Makale Bilgileri
DergiPolycyclic Aromatic Compounds
Yayın TarihiEkim 2016
Cilt / Sayfa36 · 613-627
Scopus ID2-s2.0-84945237863
Özet
Calix[4]arene amide derivatives were employed as new additives within the sol-gel encapsulation of lipase from Candida rugosa (CRL) to improve its catalytic properties. Evaluation of catalytic activity of the encapsulated lipases was acheived by enantioselective hydrolysis of both racemates, Naproxen methyl ester and 2-phenoxypropionic acid methyl ester, in aqueous buffer solution/isooctane reaction system. Results show that enantioselectivity was improved by using calix[4]arene amide derivatives-based encapsulated lipases. The reaction of naproxen methyl ester resulted in 47.6% conversion (x) in 24 h with 88.9% enantiomeric excess of substrate (ees), analogous to an enantioselectivity (E) value of 297 (E = 137 for the encapsulated free enzyme). The conversion of 2-phenoxypropionic acid methyl ester, obtained was 48.4% with E value of 327, enantiomeric excess of substrate (ees) of 92% for the reaction time of 1 h (E = 211 for the encapsulated free enzyme).
Yazarlar (3)
1
Arzu Uyanik
2
N. Sen
3
Mustafa Yilmaz
Anahtar Kelimeler
2-Phenoxypropionic acid
calix[4]arene
enantioselectivity
lipase
naproxen
sol-gel encapsulation
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
6
Atıf
3
Yazar
6
Anahtar Kelime