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“Turn-on” fluorescence probe for Al (III) and Hg (II) ions in aqueous medium: Synthesis, characterization, cytotoxicity, visual results in solution and cancer cells

Journal of Molecular Liquids · Şubat 2022

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YÖKSİS Kayıtları
"Turn-on" fluorescence probe for Al (III) and Hg (II) ions in aqueous medium: Synthesis, characterization, cytotoxicity, visual results in solution and cancer cells
JOURNAL OF MOLECULAR LIQUIDS · 2022 SCI-Expanded
DOÇENT MEHMET OĞUZ →
"Turn-on" fluorescence probe for Al (III) and Hg (II) ions in aqueous medium: Synthesis, characterization, cytotoxicity, visual results in solution and cancer cells
JOURNAL OF MOLECULAR LIQUIDS · 2022 SCI-Expanded
PROFESÖR AHMET KOÇAK →
Turn-on\u201d fluorescence probe for Al (III) and Hg (II) ions in aqueous medium: Synthesis, characterization, cytotoxicity, visual results in solution and cancer cells
Journal of Molecular Liquids · 2022 SCI
PROFESÖR MUSTAFA YILMAZ →

Makale Bilgileri

DergiJournal of Molecular Liquids
Yayın TarihiŞubat 2022
Cilt / Sayfa348
Özet In this study, An efficient OFF–ON fluorescent compound integrated with nitrobenzofurazan and phenolphthalein (NBFP) has been prepared for the detection of metals ions. NBFP was characterized with 1H NMR, 13C NMR, COSY-NMR, FTIR, and Mass spectrometry. The fluorescent response towards metal ions displayed that NBFP is selective for Hg (II) and Al (III), with a detection limit of 14.7 µM and 16.3 µM for Hg(II) and Al(III), respectively. Job's plot for NBFP + Hg (II) complex, and NBFP + Al (III) complex confirmed the 1:2 ligand–metal stoichiometry. Binding constant (Ksv) from Stern-Volmer equation was found to be 1.60 × 102 M−1 for NBFP + Hg (II) complex and 9.25 × 102 M−1 for NBFP + Al (III) complex respectively, indicating a strong interaction between ligand and selective metal ions in the presence of other ions. The quantum yield of NBFP was found to be ΦL = 0.028, exhibiting a weak and wide emission band. Cytotoxicity of NBFP has been evaluated before application in living cell fluorescent imaging for the detection of metal ions. The result showed that NBFP exhibits good biocompatibility in living cells and displayed a good response for the detection of Al (III) and Hg (II) ions in living cells using the confocal microscope.

Yazarlar (5)

1
Mehmet Oguz
2
Alev Oguz
3
Asif Ali Bhatti
4
Ahmet Kocak
5
Mustafa Yilmaz

Anahtar Kelimeler

Cytotoxicity Fluorescent Living cell imaging Metal ions Nitrobenzofurazan Phenolphthalein

Kurumlar

Government College University Hyderabad
Hyderabad Pakistan
Selçuk Üniversitesi
Selçuklu Turkey

Metrikler

4
Atıf
5
Yazar
6
Anahtar Kelime

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